LY 379268

CAS No.: 191471-52-0

Chemical Name:: LY 379268

Synonyms: CS-1087;LY397268;LY 379268;(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid;2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid,4-amino-,(1R,4R,5S,6R)-

CBNumber:: CB5841046

Molecular Formula:: C7H9NO5

Molecular Weight:: 187.15

MOL File:: 191471-52-0.mol

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

LY 379268 Properties

Boiling point	413.9±45.0 °C(Predicted)
Density	1.716±0.06 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	Soluble in H2O or NaOH
form	solid
pka	1.81±0.40(Predicted)
color	White
Water Solubility	Soluble to 20 mM in water and to 100 mM in 1eq. NaOH

LY 379268 Chemical Properties,Uses,Production

Uses

LY 379268 is a group II metabotropic glutamate receptors (mGlu2/3) receptor agonist (1,2). Studies have shown that LY379268 significantly attenuated cocaine-induced increases in DA in nonhuman primates.

Biological Activity

Highly selective group II mGlu receptor agonist (EC 50 values are 2.69 and 4.48 nM for hmGlu 2 and hmGlu 3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Provides protection against NMDA-mediated cell death in vitro and offers almost complete protection against CA1 hippocampal damage following global ischemia in gerbils. Orally and systemically active.

LY 379268 Preparation Products And Raw materials

Raw materials

Preparation Products

LY 379268 Suppliers

Global( 50)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3136	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48467	58	Inquiry
Shanghai Easy CDMO Co.,Ltd	021-61734564	China	10010	58	Inquiry
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	China	8141	58	Inquiry
Shanghai Universal Biotech Co.,Ltd	18768175414	China	24998	58	Inquiry
Nantong Hi-Future Biotechnology Co., Ltd	18051384581	China	3059	58	Inquiry
Cayman Chemical Company	(800) 364-9897	United States	6618	81	Inquiry
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	China	8740	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Aladdin Scientific	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
Shanghai Easy CDMO Co.,Ltd	58
MedBioPharmaceutical Technology Inc	58
Shanghai Universal Biotech Co.,Ltd	58
Nantong Hi-Future Biotechnology Co., Ltd	58
Cayman Chemical Company	81
Shanghai Yifei Biotechnology Co. , Ltd.	58

191471-52-0(LY 379268)Related Search:

1-[5-ETHYL-2-HYDROXY-4-[[6-METHYL-6-(1H-TETRAZOL-5-YL)HEPTYL]OXY]PHENYL]ETHANONE LY-404039 LY3143921 LY 2606368 LY-2940094

LY2109761 LY 294002 HYDROCHLORIDE 3-AMINOTETRAHYDROFURAN-3-CARBOXYLIC ACID (2S,3S,4S)-2-METHYL-2-(CARBOXYCYCLOPROPYL)GLYCINE DL-2-ISOPROPYLSERINE

(2S,1'S,2'S)-2-(CARBOXYCYCLOPROPYL)GLYCINE L-2-Aminoadipic acid DL-2-ISOBUTYLSERINE LY 379268

chevron_left

1of3

chevron_right

LY 379268 2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid,4-amino-,(1R,4R,5S,6R)- (1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid LY397268 CS-1087 191471-52-0 AMINOACID Glutamate