5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine

5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine Structure
CAS No.
799842-07-2
Chemical Name:
5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine
Synonyms
Z8;Rosuvastatin Z-8;Rosuvastatin Impurity 103;Rosuvastatin Impurity 079;Rosuvastatin Intermediate Z8;rosuvastatin intermediates Z-8;Rosuvastatin Bromomethyl Impurity;: 5-(BroMoMethyl)-4-(4-fluorophenyl)-6-isopropyl-2;5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(met...;N-[5-bromomethyl-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-
CBNumber:
CB61508639
Molecular Formula:
C16H19BrFN3O2S
Molecular Weight:
416.31
MOL File:
799842-07-2.mol
MSDS File:
SDS
Modify Date:
2023/7/11 16:12:39

5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine Properties

Boiling point 531.2±60.0 °C(Predicted)
Density 1.466
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -0.77±0.10(Predicted)
CAS DataBase Reference 799842-07-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine Chemical Properties,Uses,Production

Uses

5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine is an impurity of Rosuvastatin (R700500), which is a selective, competitive HMG-CoA reductase inhibitor.

5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-Methyl-N-MethylsulfonylaMino)PyriMidine PRODUCT:CheMical naMe:Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-Methyl-N-MethylsulfonylaMino)PyriMidine 5-(BROMOMETHYL)-4(FLUOROPHENYL)6-ISOPROPYL-2METHYL(METHYLSULFONYL ) AMINOPYRIMIDINE N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropropyl-pyrimidine-2-yl]-N-methylmethane sulfonamide MethanesulfonaMide, N-[5-(broMoMethyl)-4-(4-fluorophenyl)-6-(1-Methylethyl)-2-pyriMidinyl]-N-Methyl- Rosuvastatin Bromomethyl Impurity rosuvastatin intermediates Z-8 N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropropyl-pyrimidine-2-yl]-N-methylmethane sulfonamid N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamid N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropylpyrimidine-2-yl]-N-methyl methane sulfonamide : 5-(BroMoMethyl)-4-(4-fluorophenyl)-6-isopropyl-2 4-(4-Fluorophenyl)-5-broMineMethyl-6-Isopropyl-2-(N-Methyl-N-MethylsulfonylaMino)PyriMidine N-[5-bromomethyl-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide 5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine Chemical name:Diphenyl[4-(4-fluorophenyl)-6-isopropyl-2-(N-Methyl-N-Methylsulfonylamino)Pyrimidine 5-(Bromomethyl)-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(met... 5-(Bromomethyl)-4-(4-Fluorophenyl)-6-Isopropyl-2 -[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidine 5-Bromomethyl 4 Flurophenyl 6-Isopropyl 2 Methyl Methyl Sulf Onyl Amino Pyrimidine N-(4-(4-Fluorophenyl)-5-bromomethyl-6- isopropylpyrimidin-2-yl)-N-methyl methane sulfonamide Rosuvastatin Impurity 079 Rosuvastatin Z-8 Rosuvastatin Impurity 103 5-(Bromomethyl)-4-(4-Fluorophenyl)-6-Isopropyl-3-[Methyl(Methylsulfonyl)Amino]Pyrimidine 98% Z8 Rosuvastatin Intermediate Z8 N-(5-(bromomethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide? (Rosuvastatin Impurity) N-[5-bromomethyl-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl- N-[5-bromomethyl-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide (BRO-Z7 ) 799842-07-2 C16H19BrFN3O2S Fluorine series pyrimidine rosuvastatin intermediates