ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Stem Cells & Wnt >Wnt / beta-catenin inhibitors >FH 535

FH 535

FH 535 Structure
CAS No.
108409-83-2
Chemical Name:
FH 535
Synonyms
FH 535;CS-1433;FH 535(FH-535);FH 535 USP/EP/BP;FH535;FH 535;FH-535;β-Catenin/Tcf Inhibitor, FH535;2,5-Dichloro-N-(2-Methyl-4-nitrophenyl)benzenesulfonaMide;N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonaMide;Benzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-;β-Catenin/Tcf Inhibitor, FH535 - CAS 108409-83-2 - Calbiochem
CBNumber:
CB62552602
Molecular Formula:
C13H10Cl2N2O4S
Molecular Weight:
361.2
MOL File:
108409-83-2.mol
Modify Date:
2023/6/30 15:45:59

FH 535 Properties

Melting point 141-142℃
Boiling point 526.3±60.0 °C(Predicted)
Density 1.566±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble20mg/mL
form Yellow solid
pka 5.83±0.10(Predicted)
color Tan
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey AXNUEXXEQGQWPA-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05, GHS07
Signal word  Danger
Hazard statements  H302-H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi
Risk Statements  41
Safety Statements  36
WGK Germany  3
HS Code  29350090
NFPA 704
0
3 0

FH 535 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F5682 FH535 ≥98% (HPLC) 108409-83-2 5MG ₹10814.18 2022-06-14 Buy
Sigma-Aldrich(India) F5682 FH535 ≥98% (HPLC) 108409-83-2 25MG ₹41762.85 2022-06-14 Buy
Sigma-Aldrich(India) 219330 β-Catenin/Tcf Inhibitor, FH535 - CAS 108409-83-2 - Calbiochem The β-Catenin/Tcf Inhibitor, FH535, also referenced under CAS 108409-83-2, controls the biological activity of β-Catenin/Tcf. This small molecule/inhi 108409-83-2 10MG ₹12740 2022-06-14 Buy
Product number Packaging Price Buy
F5682 5MG ₹10814.18 Buy
F5682 25MG ₹41762.85 Buy
219330 10MG ₹12740 Buy

FH 535 Chemical Properties,Uses,Production

Chemical Properties

Dark Yellow Solid

Uses

Antagonizes Wnt/β-catenin/Tcf-mediated transcription as well as PPARγ and δ activity. Able to inhibit the recruitment of the co-activators β-catenin and GRIP1, both of which are activators for both pathways.

Biochem/physiol Actions

FH535 has the ability to block the development of colon cancer cells. It can change several cancer-associated biological processes. FH535 can also prevent PARylation of Axin2 in osteosarcoma cells.

FH 535 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 117)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24607 58 Inquiry
Wuhan Nutra Biotechnology Co.,Ltd +8617786394783 China 300 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry

FH 535 Spectrum

β-Catenin/Tcf Inhibitor, FH535 FH 535(FH-535) FH535;FH 535;FH-535 FH 535 N-(2-Methyl-4-nitrophenyl)-2,5-dichlorobenzenesulfonaMide 2,5-Dichloro-N-(2-Methyl-4-nitrophenyl)benzenesulfonaMide 2,5-Dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide FH535 β-Catenin/Tcf Inhibitor, FH535 - CAS 108409-83-2 - Calbiochem FH535, 98%, a cell-permeable compound that inhibits Wnt/β-catenin and PPAR Benzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)- FH 535 USP/EP/BP CS-1433 FH 535,Beta catenin,β-catenin,FH535,inhibit,FH-535,PPAR,Wnt,Inhibitor,Peroxisome proliferator-activated receptors 108409-83-2 API Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals