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3-Ethoxy-4-methoxy benzonitrile

3-Ethoxy-4-methoxy benzonitrile Structure
CAS No.
60758-86-3
Chemical Name:
3-Ethoxy-4-methoxy benzonitrile
Synonyms
3-ethoxy-4-Methoxybenzonitrile;Apremilast Impurity 78;Bempedoic Acid Impurity 52;Apremilast Impurity APRRC-9;3-Ethoxy-4-methoxybenzonitril;3-Ethoxy-4-methoxy bezonitrile;3-Ethoxy-4-Methoxy benzontrile;Benzonitrile, 3-ethoxy-4-Methoxy-;3-Ethoxy-4-methoxybenzonitrile >3-Ethoxy-4-methoxybenzonitrile Apremilast
CBNumber:
CB62639846
Molecular Formula:
C10H11NO2
Molecular Weight:
177.2
MOL File:
60758-86-3.mol
MSDS File:
SDS
Modify Date:
2024/4/16 18:29:06

3-Ethoxy-4-methoxy benzonitrile Properties

Melting point 70℃
Boiling point 281.9±25.0℃ (760 Torr)
Density 1.09±0.1 g/cm3 (20 ºC 760 Torr)
Flash point 109.2±16.4℃
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Light yellow
InChIKey XTIINWPNAMHVDG-UHFFFAOYSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS07
Signal word  Danger
Hazard statements  H301+H311+H331-H315-H319
Precautionary statements  P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P305+P351+P338+P337+P313-P403+P233-P405-P501
RIDADR  3439
HazardClass  6.1
PackingGroup  III
HS Code  2926907090

3-Ethoxy-4-methoxy benzonitrile price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) E1109 3-Ethoxy-4-methoxybenzonitrile min. 98.0 % 60758-86-3 5G ₹7500 2022-05-26 Buy
TCI Chemicals (India) E1109 3-Ethoxy-4-methoxybenzonitrile min. 98.0 % 60758-86-3 25G ₹16500 2022-05-26 Buy
Product number Packaging Price Buy
E1109 5G ₹7500 Buy
E1109 25G ₹16500 Buy

3-Ethoxy-4-methoxy benzonitrile Chemical Properties,Uses,Production

Chemical Properties

White to Light yellow powder to crystal

Uses

3-Ethoxy-4-methoxy benzonitrile can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Synthesis_60758-86-3
In a 100 ml flask in the, adding 3-hydroxy-4-methoxy phenyl nitrile 10g (67.11mmol), bromoethane 25 ml (335.2mmol), potassium carbonate 10.25g, dimethyl formamide 50 ml, heating and stirring to 100 ??C. TLC monitoring reaction, reaction 8h, stop heating. Natural cooling to room temperature, water 100 ml, the ethyl acetate extraction, the organic phase is dried with anhydrous sodium sulfate, ethyl acetate solvent turns on lathe does the white solid obtained 11.09g.

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Benzonitrile, 3-ethoxy-4-Methoxy- 3-Ethoxy-4-Methoxy benzontrile 3-Ethoxy-4-methoxybenzonitrile Apremilast 3-Ethoxy-4-methoxybenzonitril Apremilast Impurity 2:3-Ethoxy-4-methoxybenzonitrile 3-Ethoxy-4-methoxy bezonitrile 3-Ethoxy-4-methoxybenzonitrile > Apremilast Impurity 78 3-ethoxy-4-Methoxybenzonitrile Bempedoic Acid Impurity 52 Apremilast Impurity APRRC-9 60758-86-3 apremilast intermediates Apremilast