(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine

(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine Structure
CAS No.
608141-42-0
Chemical Name:
(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine
Synonyms
(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine;Apremilast inter2;Apremilast Impurity 55;Apremilast Intermediate II;Apremilast Intermediates 2;Apremilast Impurity HS093220;RSSYY(Lurasidone Hydrochloride)-14;Apremilast EP Impurity H (S)-Isomer;(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine;(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine
CBNumber:
CB82661858
Molecular Formula:
C12H19NO4S
Molecular Weight:
273.35
MOL File:
608141-42-0.mol
Modify Date:
2024/6/6 16:20:44

(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine Properties

Melting point 106-108oC
Boiling point 469.6±45.0 °C(Predicted)
Density 1.195±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka 6.84±0.10(Predicted)
form Solid
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2930909899

(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine Chemical Properties,Uses,Production

Uses

(1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine is an Apremilast (A729700) intermediate. Apremilast, an oral phosphodiesterase 4 inhibitor is used in the treatment of psoriatic arthritis.

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(S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine (alphaS)-3-Ethoxy-4-methoxy-alpha-[(methylsulfonyl)methyl]-benzenemethanamine (S)-2-(3-ethoxy-4-Methoxyphenyl)-1-(Methylsulphonyl)-eth-1-ylaMine Apremilast Intermediate II (1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine-N- acetyl –L-Leucine salt (1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulfonyl)-eth-2-ylamine (S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine Apremilast inter2 Apremilast Intermediates 2 (1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethan-1-amine (S)-2-[1 (3-ethoxy-4-methoxyphenyl)]-1-methanesulfonyl-2-ethylamine Apremilast Impurity HS093220 Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-, (αS)- Apremilast Impurity 55 (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamin... (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine (alphaS)-3- ethoxy -4- methoxy -alpha-[ (methylsulfonyl) methyl]-benzylamine RSSYY(Lurasidone Hydrochloride)-14 (αS)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine Apremilast Impurity 1 3-Ethoxy-4-methoxy-[(methylsulfonyl)methyl]-(S)- benzenemethanamine Apremilast EP Impurity H (S)-Isomer 608141-42-0 apremilast intermediates