ETHYLTHIOUREA
- CAS No.
- 625-53-6
- Chemical Name:
- ETHYLTHIOUREA
- Synonyms
- N-ETHYLTHIOUREA;Nsc62921;Ent 61326;ETHYLTHIOUREA;1-ETHYLTHIOUREA;ethyl-2-thiourea;Thiourea, ethyl-;Ethylthiourea,99%;1-ETHYL-2-THIOUREA;1-ethyl-2-thio-ure
- CBNumber:
- CB6416447
- Molecular Formula:
- C3H8N2S
- Molecular Weight:
- 104.17
- MOL File:
- 625-53-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/15 10:44:00
| Melting point | 108-110 °C(lit.) |
|---|---|
| Boiling point | 132 °C |
| Density | 1.055 (estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Store at RT |
| solubility | methanol: soluble25mg/mL, clear, colorless |
| form | Solid |
| pka | 14.97±0.29(Predicted) |
| color | White to Off-White |
| Water Solubility | Soluble in water (24g/L). |
| BRN | 1699551 |
| InChIKey | GMEHFXXZSWDEDB-UHFFFAOYSA-N |
| CAS DataBase Reference | 625-53-6(CAS DataBase Reference) |
| EPA Substance Registry System | Ethylthiourea (625-53-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310+P330 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 36/37/39-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YT3700000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| Toxicity | mouse,LDLo,oral,500mg/kg (500mg/kg),Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981. | |||||||||
| NFPA 704 |
|
ETHYLTHIOUREA Chemical Properties,Uses,Production
Uses
N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides
General Description
N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.
Biological Activity
Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).
Safety Profile
Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.
Purification Methods
Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]
ETHYLTHIOUREA Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD. | +86-0532-8699-9256 +8615254267723 | China | 1410 | 58 | Inquiry |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 12962 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | China | 4128 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | China | 18446 | 58 | Inquiry |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8615195660023 | China | 10814 | 58 | Inquiry |
| Weifang Wehibest Supply Chain Co.,Ltd | +8613583620690 | China | 926 | 58 | Inquiry |