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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

CAS No.: 99010-64-7

Chemical Name:: 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline

Synonyms: cas 99010-64-7;Imiquimod USP RC C;Imiquimod Impurity-C;DesaMino ChloroiMiquiMod;1H-Imidazo[4,5-c]quinoline,;IMiquiMod Related CoMpound C;Imiquimod USP Related Compound C;4-Chloro-1-isobutyl-1H-imidazo[4,5-;1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(;4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE

CBNumber:: CB6449735

Molecular Formula:: C14H14ClN3

Molecular Weight:: 259.73

MOL File:: 99010-64-7.mol

Modify Date:: 2024/1/9 10:21:27

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4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Properties

Melting point	139-140 °C(Solv: isopropanol (67-63-0))
Boiling point	427.5±48.0 °C(Predicted)
Density	1.29±0.1 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Solid
pka	3.15±0.30(Predicted)
color	White to Off-White
CAS DataBase Reference	99010-64-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2934990002

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Chemical Properties,Uses,Production

Description

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is a chemical product that has been used as a photosynthetic activator in weed science and pest control. It has been shown to significantly increase the growth rate of wheat, soybean, and oilseed crops. It is also effective at controlling weeds by inhibiting their ability to produce chlorophyll, thereby preventing them from photosynthesizing. 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline has also been shown to be an effective herbicide for agricultural use.

Uses

Desamino Chloroimiquimod (Imiquimod USP Related Compound C) is a pharmacologically active compound related to Imiquimod (I475000), an immune response modifier. It stimulates the production of Interferon-a.

Synthesis

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline is prepared by the reaction of 2-chloro-N⁴-(2-methylpropyl)quinoline-3,4-diamine and orthoformic acid triethyl ester. The specific synthesis steps are as follows:
A suspension of 2-chloro-N4 -(2-methylpropyl)-3,4-quinolinediamine (35 g) and triethylorthoformate (52.3 g, 2.5 eq) was heated at 145° C. for 10 h, during which time ethanol was removed by distillation. The resulting mixture was cooled to room temperature and the solid was removed by filtration. The solid was dissolved in hydrochloric acid (100 mL, 4N). The resulting solution was added to a solution of sodium hydroxide. The precipitate was filtered and washed with water to afford the product 4-chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline in 92% yield.

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Preparation Products And Raw materials

Raw materials

Preparation Products

4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline Suppliers

Global( 175)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Sris Synthesis Pvt Ltd.,	+91-9989522441 +91-9989522441	Hyderabad, India	282	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	16209	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21669	55	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9337	55	Inquiry
Shanxi Naipu Import and Export Co.,Ltd	+86-13734021967 +8613734021967	China	1011	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29898	58	Inquiry

Supplier	Advantage
Sris Synthesis Pvt Ltd.,	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
CLEARSYNTH LABS LTD.	58
A.J Chemicals	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Shanxi Naipu Import and Export Co.,Ltd	58
career henan chemical co	58

99010-64-7(4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline)Related Search:

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RESIQUIMOD 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline 4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 98%MIN

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4-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINE 4-CHLORO-1-ISOBUTYL-1H-IMIDAZOBEN[4,5-C]QUINOLINE 1-[2-METHYLPROPYL]-1H-2-CHLOROIMIDAZO-[4,5-C]QUINOLINE 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-(2-METHYLPROPYL) 4-Chloro-1-(2-methylpropyl)-1H-imidazo-(4,5c)quinolinone 2-CHLORO-1-(2-METHYLPROPYL)-1H-IMIDAZO[4,5-C]QUINOLINONE 1H-Imidazo[4,5-c]quinoline, 4-CHLORO-1-ISOBUTYL-1H-IMIBENZO(4,5-C)QUINOLINE 1H-Imidazo[4,5-c]quinoline, -chloro-1-(2-methylpropyl)- 1H-Imidazo[4,5-c]quinolinone,2-chloro-1-(2-methylpropyl) Imiquimod Related Compound C (25 mg) (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline) 1-H-IMIDAZO[4,5-C]QUINOLINONE,4-CHLORO-1-(2-METHYL PROPYL) IMiquiMod Related CoMpound C DesaMino ChloroiMiquiMod 4-Chloro-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline###4-Chloro-1-(2-methylpropyl)-1H-imidazole[4,5-c]quinoline 1H-IMIDAZO[4,5-C]QUINOLINE, 4-CHLORO-1-( 4-chloro-1-(2-methylpropyl)imidazo[4,5-c]quinoline Imiquimod USP Related Compound C 4-Chloro-1-isobutyl-1H-imidazo[4,5- Imiquimod USP RC C Imiquimod Impurity 3 (Imiquimod Related Compound C) Imiquimod Impurity-C Imiquimod Related Compound C (4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline) (1338346) 4-CHLORO-1-ISOBUTYL-1H-IMIDAZO (4,5'D)QUINOLINE cas 99010-64-7 99010-64-7 C14H14ClN3 Quinolines, Quinazolines and derivatives Intermediates of Imiquimod API intermediates