2,4-Thiazolidinedione

2,4-Thiazolidinedione Structure
CAS No.
2295-31-0
Chemical Name:
2,4-Thiazolidinedione
Synonyms
THIAZOLIDINE-2,4-DIONE;TZD;Thiazolidinedione;2,4-Thiazolidindione;U 25560;idinedione;usafek-5496;2,4-ThiazoL;USAF ek-5496;AURORA 23272
CBNumber:
CB6675365
Molecular Formula:
C3H3NO2S
Molecular Weight:
117.13
MOL File:
2295-31-0.mol
MSDS File:
SDS
Modify Date:
2024/10/25 16:21:11

2,4-Thiazolidinedione Properties

Melting point 125-127 °C (lit.)
Boiling point 178-179 °C (19 mmHg)
Density 1.408 (estimate)
vapor pressure 0Pa at 25℃
refractive index 1.5130 (estimate)
Flash point 178-179°C/19mm
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 6.50±0.10(Predicted)
form Crystalline Powder
color Slightly yellow
Water Solubility Soluble in water (30 mg/ml at 3°C), methanol, DMSO, ethanol, and ethyl ether.
BRN 110700
InChIKey ZOBPZXTWZATXDG-UHFFFAOYSA-N
LogP -0.29 at 25℃
CAS DataBase Reference 2295-31-0(CAS DataBase Reference)
NIST Chemistry Reference 2,4-Thiazolidinedione(2295-31-0)
EPA Substance Registry System 2,4-Thiazolidinedione (2295-31-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Warning
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310a-P321-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
RTECS  XJ5775000
TSCA  Yes
HazardClass  IRRITANT
HS Code  29341000
NFPA 704
0
1 0

2,4-Thiazolidinedione price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 375004 2,4-Thiazolidinedione technical grade, 90% 2295-31-0 25G ₹3570 2022-06-14 Buy
Sigma-Aldrich(India) 375004 2,4-Thiazolidinedione technical grade, 90% 2295-31-0 100G ₹6900 2022-06-14 Buy
TCI Chemicals (India) T1990 2,4-Thiazolidinedione min. 98.0 % 2295-31-0 25G ₹3700 2022-05-26 Buy
TCI Chemicals (India) T1990 2,4-Thiazolidinedione min. 98.0 % 2295-31-0 100G ₹5100 2022-05-26 Buy
TCI Chemicals (India) T1990 2,4-Thiazolidinedione min. 98.0 % 2295-31-0 500G ₹9100 2022-05-26 Buy
Product number Packaging Price Buy
375004 25G ₹3570 Buy
375004 100G ₹6900 Buy
T1990 25G ₹3700 Buy
T1990 100G ₹5100 Buy
T1990 500G ₹9100 Buy

2,4-Thiazolidinedione Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Powder

Uses

2,4-Thiazolidinedione may be used in the synthesis of sixteen 5-arylidene-2,4-thiazolidinediones, via ultrasound-promoted aldol condensation reaction. It may be used as starting material for the synthesis of drugs with antihyperglycemic activity.

Definition

ChEBI: A thiazolidenedione carrying oxo substituents at positions 2 and 4.

General Description

2,4-Thiazolidinedione is a well-known peroxisome proliferator-activated receptors (PPAR) activator. Its effect on aging process using kidneys from Fischer 344 rats has been reported. A library of conjugates of 2,4-thiazolidinedione has been synthesized by Knoevenagel condensation followed by reduction using hydrogen gas and Pd/C catalyst. Knoevenagel condensation of various aromatic aldehydes with 2,4-thiazolidinedione in polyethylene glycol-300 has been reported.

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2,4-Thiazolidinedione, 99% 100GR 2,4-Thiazolidinedione, 99% 25GR thiazolidin-2,4-dione 2,4-Thiazolidinedione technical grade, 90% 2, 4 - Margaret diketone OTAVA-BB BB7112440002 TIMTEC-BB SBB000047 2,4(3H,5H)-Thiazoledione 2,4-Dioxothiazolidine Thiazolidinedione-2,4 USAF ek-5496 usafek-5496 AURORA 23272 2,3,4,5-TETRAHYDROTHIAZOLE-2,4-DIONE 1,3-Thiazolane-2,4-dione 1,3-Thiazolane-2,4-dione, 2,4-Dioxo-1,3-thiazolidine 1,3-THIAZOLIDINE-2,4-DIONE 2,4-DIKETOTHIAZOLIDINE 2,4-THIAZOLIDINEDIONE 2,4-Thiazolidinedione 、Thiazolidine-2,4-dione AKOS B029064 2,4-Thiadolidinedione 2,4(3H,5H)-Thiazoledion U 25560 2,4-Thiazolidinedione ,99% 2,4-Thiazolinedione 2,4-THIAZOLIDINEDIONE, TECH., 90% 2,4-Thiazolidondione 2,4-Thiozolidinedione 1,3-Thiazolidine-2,4-dione 98% Thiazoline-2,4-dione(2,4-thiazolidinedion) 2,4-THIAZOLIDINEDIONE 98% 2,4-ThiazoL idinedione 2,4-THIZAOLODINE 2,4-Thiazolidinedione > 2,4-Thiazolidinedione (P) Thiazolidin-2,4-dion TZD THIAZOLIDINE-2,4-DIONE Thiazolidinedione 2,4-Thiazolidindione Thiazolidinedione (6CI) Pioglitazone impurity thiazolidine-2,4-dione 2295-31-0 2295-31-2 C3H3NO2S C3H2KNO2S Building Blocks Heterocyclic Building Blocks Thiazoles Thiazolines/Thiazolidines Starting Raw Materials & Intermediates PHARMACEUTICAL INTERMEDIATES Sulphur Derivatives Sulfur compounds blocks Heterocycles