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Pioglitazone hydrochloride

CAS No.: 112529-15-4

Chemical Name:: Pioglitazone hydrochloride

Synonyms: PIOGLITAZONE HCL;ACTOS;Piog;PiogL;AD-4833;U-72107E;U-72107A;itazone HydrochL;$350/50G,99%,IN STOCK;Pioglitazone Hydro...

CBNumber:: CB0411844

Molecular Formula:: C19H21ClN2O3S

Molecular Weight:: 392.9

MOL File:: 112529-15-4.mol

MSDS File:: SDS

Modify Date:: 2024/12/6 22:41:32

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Pioglitazone hydrochloride Properties

Melting point	193-194°C
RTECS	XJ5813440
storage temp.	2-8°C
solubility	DMSO: ≥10mg/mL
form	powder
color	white to off-white
Water Solubility	Soluble in water (<1 mg/ml at 25°C), DMF, methanol, ethanol (4 mg/ml at 25°C), and DMSO (79 mg/ml at 25°C).
Merck	14,7452
BCS Class	2
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey	GHUUBYQTCDQWRA-UHFFFAOYSA-N
CAS DataBase Reference	112529-15-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P264-P280i-P305+P351+P338-P337+P313

Hazard Codes

Risk Statements

36/38-36

Safety Statements

22-24/25-26

WGK Germany

HazardClass

IRRITANT

HS Code

29341000

NFPA 704

	1
2		0

Pioglitazone hydrochloride price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	E6910	Pioglitazone hydrochloride ≥98% (HPLC)	112529-15-4	10MG	₹8746.6	2022-06-14	Buy
Sigma-Aldrich(India)	PHR1632	Pioglitazone hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material	112529-15-4	500MG	₹12004.93	2022-06-14	Buy
Sigma-Aldrich(India)	E6910	Pioglitazone hydrochloride ≥98% (HPLC)	112529-15-4	50MG	₹32258.5	2022-06-14	Buy
TCI Chemicals (India)	P1901	Pioglitazone Hydrochloride	112529-15-4	5G	₹14600	2022-05-26	Buy
TCI Chemicals (India)	P1901	Pioglitazone Hydrochloride	112529-15-4	25G	₹20800	2022-05-26	Buy

Product number	Packaging	Price	Buy
E6910	10MG	₹8746.6	Buy
PHR1632	500MG	₹12004.93	Buy
E6910	50MG	₹32258.5	Buy
P1901	5G	₹14600	Buy
P1901	25G	₹20800	Buy

Pioglitazone hydrochloride Chemical Properties,Uses,Production

Description

Pioglitazone is a new orally active thiazolidinedione (TZD) launched in the US for the treatment of non-insulin dependent diabetes mellitus (NIDDM). It can be synthesized in 4 steps, the last one transforming an alphabromoester into thiazolidine with thiourea. As with other representatives in this class, it potently activates the nuclear receptor peroxisome proliferator-activated receptor gamma which is believed to be involved in the regulation of insulin resistance and adipogenesis. In several obese and obese diabetic animal models, treatment with Pioglitazone resulted in reductions in plasma glucose and serum lipids. In clinical studies, Pioglitazone at a once daily oral dose of 15-45 mg, as monotherapy or in combination with non-TZDs or insulin, was shown to significantly improve glycemic control in type-2 diabetes and demonstrated a beneficial effect on insulin resistance and other clinically relevant parameters as plasma levels of triglycerides or HDL-cholesterol. Pioglitazone is reported to be safe and well tolerated and is said to have a lower occurrence of hepatic toxicity as well as a low probability for drug interaction.

Chemical Properties

Colourless Prisms

Uses

Pioglitazone hydrochloride is a euglycemic agent,used as an antidiabetic.

General Description

Pioglitazone hydrochloride is an oral antidiabetic agent used in the treatment of type 2 diabetes mellitus (also known as non-insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes.

Pioglitazone hydrochloride Preparation Products And Raw materials

Raw materials

Methyl acrylate Hydrogen bromide Sodium Methoxide COPPER(II) OXIDE 5-Ethyl-2-pyridineethanol

Palladium hydroxide 4-Fluoronitrobenzene Sodium acetate Sodium hydride

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Preparation Products

Pioglitazone

Pioglitazone hydrochloride Suppliers

Global( 696)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Jigs Chemical ltd	+919099003427	Gujarat, India	239	58	Inquiry
Vardhaman P Golechha	9704422000	Telangana, India	292	58	Inquiry
Dr. Reddy's Laboratories Ltd	+91-4049002900 +91-4049002900	Hyderabad, India	165	58	Inquiry
Nivika Chemo Pharma Pvt Ltd	+91-9824176501 +91-9824176501	Gujarat, India	15	58	Inquiry
Vidgas science and technologies Pvt Ltd	+91-9030019844 +91-9030019844	Telangana, India	76	58	Inquiry
USV Pvt Ltd	+91-2267861111 +91-2225564048	Maharashtra, India	36	58	Inquiry
Aurobindo Pharma Limited	+914066725000	Telangana, India	112	58	Inquiry
Apotex Pharmachem India Pvt Ltd	+91-8022891034 +91-8022891000	Karnataka, India	109	58	Inquiry
Cipla Ltd	+912224826000	Maharashtra, India	133	58	Inquiry
JPN Pharma Pvt Ltd	+919833233531	Maharashtra, India	33	58	Inquiry

Supplier	Advantage
Jigs Chemical ltd	58
Vardhaman P Golechha	58
Dr. Reddy's Laboratories Ltd	58
Nivika Chemo Pharma Pvt Ltd	58
Vidgas science and technologies Pvt Ltd	58
USV Pvt Ltd	58
Aurobindo Pharma Limited	58
Apotex Pharmachem India Pvt Ltd	58
Cipla Ltd	58
JPN Pharma Pvt Ltd	58

Pioglitazone hydrochloride Spectrum

Pioglitazone hydrochloride(112529-15-4)¹HNMR

112529-15-4(Pioglitazone hydrochloride)Related Search:

Rosiglitazone Liraglutide Repaglinide Melatonine WY-14643

MK-2206 2HCl HS-173 Vorinostat 17-AAG 4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide

Hydroxypioglitazone Pioglitazone Sulfonic Acid IMpurity 2-[2-(4-BroMophenoxy)ethyl]-5-ethylpyridine a-[(Aminocarbonyl)thio]-4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzenepropanoic Acid Ethyl Ester Hydroxy Pioglitazone (M-II) (Mixture of Diastereomers)

4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyaldehyde Pioglitazone Impurity 5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-2-imino-4-thiazolidinone

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5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzylidine]-2,4-thiazolidinedionehydrochloride AD-4833 pioglitazone hydrochioride Pioditazone hydrochloride PIODLITAZONE HYDROCHLORIC 5-{4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL}-THIAZOLIDINE-2,4-DIONE HCL 5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}- 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride Pioglitazone Hydrochloride (50 mg) (5R)-5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}Methyl)-1,3-thiazolidine-2,4-dione Effects of pioglitazone 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione Hydrochloride [5-[[4-[2-(5-ETHYL-PYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]-2,4-] THIAZOLIDINEDIONE HCL (R)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride Pioglitazone for system suitability 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione,hydrochloride (1:1) U-72107E Pioglitazone hydrochloride, >=99% thiazolidinedione hydrochloride 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride U-72107A 5-((4-(2-(5-ETHYL-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-2,4-THIAZOLIDINEDIONE, HCL [5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride PIOGLITAZONE HYDROCHLORIDE (RS)-5-(4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl)thiazolidine-2,4-dione hydrochloride Pioglitazone hydrochloride, 99%, a receptor-gamma (PPARgamma) agonist (+-5-[[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY] PHENYL]METHYL]-2 4-] THIAZOLIDINEDIONE H YDROCHLORIDE(PIOGLITAZONE HCL) Pioglitazone hydrochloride, 99%, receptor-gamma (PPARgamma) agonist $350/50G,99%,IN STOCK Pioglitazone hydrochloride SALT Pioglitazone for system suitability CRS Pioglitazone hydrochloride CRS PioglitazoneHydrochloride> Pioglitazone Hydrochloride RS itazone HydrochL Piog Pioglitazone hydrochloride Solution in Methanol, 100μg/mL PiogL Pioglitazone hydrochloride USP/EP/BP Pioglitazone hydrochloride5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]Methyl]-2,4-thiazolidinedionehydrochloride Pioglitazone HydrochlorideQ: What is Pioglitazone Hydrochloride Q: What is the CAS Number of Pioglitazone Hydrochloride Q: What is the storage condition of Pioglitazone Hydrochloride Q: What are the applications of Pioglitazone Hydrochloride Pioglitazone hydrochloride, 98%, Pioglitazone Hydrochloride (1539905) ACTOS PIOGLITAZONE HCL Pioglitazone hydrochloride (RS)-5-(4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl)thiazolidine-2,4- dione hydrochloride Pioglitazone Hydro... C16216000 PioglitazonEHydrochloride Pioglitazone hydrochloride, PPAR-gamma agonist 112529-15-4 12529-15-4 C19H20N2O3SHCl C19H20N2O3SxHCl C20H21N2O3S C19H21N2O3ClS C19H20N2O3SClH