ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Pioglitazone hydrochloride
Pioglitazone hydrochloride
- CAS No.
- 112529-15-4
- Chemical Name:
- Pioglitazone hydrochloride
- Synonyms
- PIOGLITAZONE HCL;ACTOS;Piog;PiogL;AD-4833;U-72107E;U-72107A;itazone HydrochL;$350/50G,99%,IN STOCK;Pioglitazone Hydro...
- CBNumber:
- CB0411844
- Molecular Formula:
- C19H21ClN2O3S
- Molecular Weight:
- 392.9
- MOL File:
- 112529-15-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | 193-194°C |
|---|---|
| RTECS | XJ5813440 |
| storage temp. | 2-8°C |
| solubility | DMSO: ≥10mg/mL |
| form | powder |
| color | white to off-white |
| Water Solubility | Soluble in water (<1 mg/ml at 25°C), DMF, methanol, ethanol (4 mg/ml at 25°C), and DMSO (79 mg/ml at 25°C). |
| Merck | 14,7452 |
| BCS Class | 2 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChIKey | GHUUBYQTCDQWRA-UHFFFAOYSA-N |
| CAS DataBase Reference | 112529-15-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280i-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/38-36 | |||||||||
| Safety Statements | 22-24/25-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29341000 | |||||||||
| NFPA 704 |
|
Pioglitazone hydrochloride price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E6910 | Pioglitazone hydrochloride ≥98% (HPLC) | 112529-15-4 | 10MG | ₹8746.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1632 | Pioglitazone hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 112529-15-4 | 500MG | ₹12004.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E6910 | Pioglitazone hydrochloride ≥98% (HPLC) | 112529-15-4 | 50MG | ₹32258.5 | 2022-06-14 | Buy |
| TCI Chemicals (India) | P1901 | Pioglitazone Hydrochloride | 112529-15-4 | 5G | ₹14600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | P1901 | Pioglitazone Hydrochloride | 112529-15-4 | 25G | ₹20800 | 2022-05-26 | Buy |
Pioglitazone hydrochloride Chemical Properties,Uses,Production
Description
Pioglitazone is a new orally active thiazolidinedione (TZD) launched in the US for the treatment of non-insulin dependent diabetes mellitus (NIDDM). It can be synthesized in 4 steps, the last one transforming an alphabromoester into thiazolidine with thiourea. As with other representatives in this class, it potently activates the nuclear receptor peroxisome proliferator-activated receptor gamma which is believed to be involved in the regulation of insulin resistance and adipogenesis. In several obese and obese diabetic animal models, treatment with Pioglitazone resulted in reductions in plasma glucose and serum lipids. In clinical studies, Pioglitazone at a once daily oral dose of 15-45 mg, as monotherapy or in combination with non-TZDs or insulin, was shown to significantly improve glycemic control in type-2 diabetes and demonstrated a beneficial effect on insulin resistance and other clinically relevant parameters as plasma levels of triglycerides or HDL-cholesterol. Pioglitazone is reported to be safe and well tolerated and is said to have a lower occurrence of hepatic toxicity as well as a low probability for drug interaction.
Chemical Properties
Colourless Prisms
Uses
Pioglitazone hydrochloride is a euglycemic agent,used as an antidiabetic.
General Description
Pioglitazone hydrochloride is an oral antidiabetic agent used in the treatment of type 2 diabetes mellitus (also known as non-insulin-dependent diabetes mellitus (NIDDM) or adult-onset diabetes.
Pioglitazone hydrochloride Preparation Products And Raw materials
Raw materials
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Global( 682)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Vardhaman P Golechha | 9704422000 | Telangana, India | 294 | 58 | Inquiry |
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| Nivika Chemo Pharma Pvt Ltd | +91-9824176501 +91-9824176501 | Gujarat, India | 15 | 58 | Inquiry |
| Vidgas science and technologies Pvt Ltd | +91-9030019844 +91-9030019844 | Telangana, India | 76 | 58 | Inquiry |
| USV Pvt Ltd | +91-2267861111 +91-2225564048 | Maharashtra, India | 36 | 58 | Inquiry |
| Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
| Apotex Pharmachem India Pvt Ltd | +91-8022891034 +91-8022891000 | Karnataka, India | 109 | 58 | Inquiry |
| Cipla Ltd | +912224826000 | Maharashtra, India | 133 | 58 | Inquiry |
| JPN Pharma Pvt Ltd | +919833233531 | Maharashtra, India | 33 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| Vardhaman P Golechha | 58 |
| Dr. Reddy's Laboratories Ltd | 58 |
| Nivika Chemo Pharma Pvt Ltd | 58 |
| Vidgas science and technologies Pvt Ltd | 58 |
| USV Pvt Ltd | 58 |
| Aurobindo Pharma Limited | 58 |
| Apotex Pharmachem India Pvt Ltd | 58 |
| Cipla Ltd | 58 |
| JPN Pharma Pvt Ltd | 58 |
112529-15-4(Pioglitazone hydrochloride)Related Search:
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5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzylidine]-2,4-thiazolidinedionehydrochloride
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pioglitazone hydrochioride
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PIODLITAZONE HYDROCHLORIC
5-{4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL}-THIAZOLIDINE-2,4-DIONE HCL
5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}-
5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride
5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride
Pioglitazone Hydrochloride (50 mg)
(5R)-5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}Methyl)-1,3-thiazolidine-2,4-dione
Effects of pioglitazone
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione Hydrochloride
[5-[[4-[2-(5-ETHYL-PYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]-2,4-] THIAZOLIDINEDIONE HCL
(R)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione monohydrochloride
Pioglitazone for system suitability
5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione,hydrochloride (1:1)
U-72107E
Pioglitazone hydrochloride, >=99%
thiazolidinedione hydrochloride
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride
U-72107A
5-((4-(2-(5-ETHYL-2-PYRIDINYL)ETHOXY)PHENYL)METHYL)-2,4-THIAZOLIDINEDIONE, HCL
[5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-] thiazolidinedione hydrochloride
PIOGLITAZONE HYDROCHLORIDE
(RS)-5-(4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl)thiazolidine-2,4-dione hydrochloride
Pioglitazone hydrochloride, 99%, a receptor-gamma (PPARgamma) agonist
(+-5-[[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY] PHENYL]METHYL]-2 4-] THIAZOLIDINEDIONE H YDROCHLORIDE(PIOGLITAZONE HCL)
Pioglitazone hydrochloride, 99%, receptor-gamma (PPARgamma) agonist
$350/50G,99%,IN STOCK
Pioglitazone hydrochloride SALT
Pioglitazone for system suitability CRS
Pioglitazone hydrochloride CRS
PioglitazoneHydrochloride>
Pioglitazone Hydrochloride RS
itazone HydrochL
Piog
Pioglitazone hydrochloride Solution in Methanol, 100μg/mL
PiogL
Pioglitazone hydrochloride USP/EP/BP
Pioglitazone hydrochloride5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]Methyl]-2,4-thiazolidinedionehydrochloride
Pioglitazone HydrochlorideQ: What is
Pioglitazone Hydrochloride Q: What is the CAS Number of
Pioglitazone Hydrochloride Q: What is the storage condition of
Pioglitazone Hydrochloride Q: What are the applications of
Pioglitazone Hydrochloride
Pioglitazone hydrochloride, 98%,
Pioglitazone Hydrochloride (1539905)
ACTOS
PIOGLITAZONE HCL
Pioglitazone hydrochloride
(RS)-5-(4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl)thiazolidine-2,4- dione hydrochloride
Pioglitazone Hydro...
112529-15-4
12529-15-4
C19H20N2O3SHCl
C19H20N2O3SxHCl
C20H21N2O3S
C19H21N2O3ClS
C19H20N2O3SClH
C19H21ClN2O3S
Cardiovascular Series