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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Pioglitazone hydrochloride

Pioglitazone hydrochloride

Pioglitazone hydrochloride Structure
  • ₹6693 - ₹32258.5
  • Product name: Pioglitazone hydrochloride
  • CAS: 112529-15-4
  • MF: C19H21ClN2O3S
  • MW: 392.9
  • EINECS:629-731-9
  • MDL Number:MFCD04975446
  • Synonyms:5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzylidine]-2,4-thiazolidinedionehydrochloride;AD-4833;pioglitazone hydrochioride;Pioditazone hydrochloride;PIODLITAZONE HYDROCHLORIC;5-{4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL}-THIAZOLIDINE-2,4-DIONE HCL;5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}-;5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride
6 prices
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 250mg
  • 500MG
  • 5G
  • 25G
  • ManufacturerALFA India
  • Product numberALF-H60507-MD
  • Product descriptionPioglitazone hydrochloride, 98%
  • Packaging250mg
  • Price₹6693
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1901
  • Product descriptionPioglitazone Hydrochloride
  • Packaging5G
  • Price₹14600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberP1901
  • Product descriptionPioglitazone Hydrochloride
  • Packaging25G
  • Price₹20800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE6910
  • Product descriptionPioglitazone hydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹32258.5
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1632
  • Product descriptionPioglitazone hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹12004.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE6910
  • Product descriptionPioglitazone hydrochloride ≥98% (HPLC)
  • Packaging10MG
  • Price₹8746.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-H60507-MD Pioglitazone hydrochloride, 98% 250mg ₹6693 2022-05-26 Buy
TCI Chemicals (India) P1901 Pioglitazone Hydrochloride 5G ₹14600 2022-05-26 Buy
TCI Chemicals (India) P1901 Pioglitazone Hydrochloride 25G ₹20800 2022-05-26 Buy
Sigma-Aldrich(India) E6910 Pioglitazone hydrochloride ≥98% (HPLC) 50MG ₹32258.5 2022-06-14 Buy
Sigma-Aldrich(India) PHR1632 Pioglitazone hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹12004.93 2022-06-14 Buy
Sigma-Aldrich(India) E6910 Pioglitazone hydrochloride ≥98% (HPLC) 10MG ₹8746.6 2022-06-14 Buy

Properties

Melting point :193-194°C
RTECS :XJ5813440
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to off-white
Water Solubility :Soluble in water (<1 mg/ml at 25°C), DMF, methanol, ethanol (4 mg/ml at 25°C), and DMSO (79 mg/ml at 25°C).
Merck :14,7452
BCS Class :2
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :GHUUBYQTCDQWRA-UHFFFAOYSA-N
CAS DataBase Reference :112529-15-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Pioglitazone hydrochloride exhibits antiinflammatory and antiarteriosclerotic effects. It is used to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress increased TNF-α mRNA produced by aspirin-induced gastric mucosal injury. Pioglitazone Hydrochloride is an activator of PPAR γ. It is a PPARγ agonist and thiazolidinedione (TZD) anti-diabetic. Pioglitazone is a selective agonist of the nuclear receptor peroxisome proliferator-activated receptor γ (PPAR-γ) and to a lesser extent PPAR-α.

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