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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Rosiglitazone

Rosiglitazone

Rosiglitazone Structure
  • ₹4500 - ₹40983.45
  • Product name: Rosiglitazone
  • CAS: 122320-73-4
  • MF: C18H19N3O3S
  • MW: 357.43
  • EINECS:924-121-1
  • MDL Number:MFCD00871760
  • Synonyms:5-(4-[2-(METHYL-PYRIDIN-2-YL-AMINO)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione;ROSIGLITAZONE;Rosiglitazone free base ;Rosiglitazone and its intermediates;ROSIGLITAZONE 99%;RosiglitazoneBase/Hcl/Maleate;5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzylidine]-2,4-thiazolidinedione
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 200MG
  • 300MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberR0106
  • Product descriptionRosiglitazone
  • Packaging200MG
  • Price₹4500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0106
  • Product descriptionRosiglitazone
  • Packaging1G
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR2408
  • Product descriptionRosiglitazone ≥98% (HPLC)
  • Packaging10MG
  • Price₹10110.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2932
  • Product descriptionRosiglitazone Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging300MG
  • Price₹20545.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR2408
  • Product descriptionRosiglitazone ≥98% (HPLC)
  • Packaging50MG
  • Price₹40983.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) R0106 Rosiglitazone 200MG ₹4500 2022-05-26 Buy
TCI Chemicals (India) R0106 Rosiglitazone 1G ₹10800 2022-05-26 Buy
Sigma-Aldrich(India) R2408 Rosiglitazone ≥98% (HPLC) 10MG ₹10110.55 2022-06-14 Buy
Sigma-Aldrich(India) PHR2932 Rosiglitazone Pharmaceutical Secondary Standard; Certified Reference Material 300MG ₹20545.85 2022-06-14 Buy
Sigma-Aldrich(India) R2408 Rosiglitazone ≥98% (HPLC) 50MG ₹40983.45 2022-06-14 Buy

Properties

Melting point :153-155 C
Boiling point :585.0±35.0 °C(Predicted)
Density :1.315±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :6.34±0.50(Predicted)
form :powder
color :White to Off-White
Merck :14,8265
CAS DataBase Reference :122320-73-4(CAS DataBase Reference)
IARC :3 (Vol. 108) 2016

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Rosiglitazone is a type of thiazolidinedione antidiabetics. Thiazolidinedione are agonists for peroxisome-proliferator–activated receptor γ (PPAR-γ). PPAR-γ receptors are ligand-activated nuclear transcription factors that modulate gene expression, lowering blood glucose primarily by increasing insulin sensitivity in peripheral tissues.
Rosiglitazone is widely used to lower blood glucose levels in patients with type 2 diabetes mellitus. Rosiglitazone functionalizes by makes the cells of the body more sensitive to the naturally produced insulin in body. It shouldn’t be used if the patient is injecting or inhaling insulin. Using rosiglitazone with insulin could increase the risk of heart failure. Patients having heart failure with symptoms or moderate to severe heart failure should not use Rosiglitazone.

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Suppliers and manufacturers

Parth Antibiotics Pvt Ltd. OCEAN TRADING CORPORATION A.R. Life Sciences Pvt Ltd A.J Chemicals CLEARSYNTH LABS LTD. TCI Chemicals (India) Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd Primarius Custom Synthesis P. Ltd. Pharma Chemicals Amegh Pharma Pvt., Ltd.