Rosiglitazone maleate
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- ₹14418.9
- Product name: Rosiglitazone maleate
- CAS: 155141-29-0
- MF: C22H23N3O7S
- MW: 473.5
- EINECS:642-163-6
- MDL Number:MFCD03427306
- Synonyms:5-((4-[2-(METHYL-2-PYRIDINYLAMINO)-ETHOXY]-PHENYL)-METHYLENE)-2,4-THIAZOLIDINEDIONE;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;ROSIGLITAZONE MALEATE;RosiglitazoneTartrate;Avandi;BRL-49653c;RSIGLITAZONEMALEATE;5-(4-(2-(Methyl(pyridin-2-yl)aMino)ethoxy)benzyl)thiazolidine-2,4-dione Maleate
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 300MG
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2513
- Product descriptionRosiglitazone maleate Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging300MG
- Price₹14418.9
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR2513 | Rosiglitazone maleate Pharmaceutical Secondary Standard; Certified Reference Material | 300MG | ₹14418.9 | 2022-06-14 | Buy |
Properties
Melting point :235-240°C
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :6.1; 6.8(at 25℃)
form :White powder
color :White
BCS Class :1
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
InChIKey :HCDYSWMAMRPMST-NTCAYCPXSA-N
CAS DataBase Reference :155141-29-0(CAS DataBase Reference)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :6.1; 6.8(at 25℃)
form :White powder
color :White
BCS Class :1
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
InChIKey :HCDYSWMAMRPMST-NTCAYCPXSA-N
CAS DataBase Reference :155141-29-0(CAS DataBase Reference)
Safety Information
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Description
Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. Rosiglitazone is a prototypical TZD that has served as a reference compound for this class. It is a potent and selective PPARγ ligand that binds to the PPARγ ligand-binding domain with a Kd value of 43 nM. It activates luciferase-based expression constructs PPARγ1 and PPARγ2 with EC50 values of approximately 30 nM and 100 nM, respectively. Rosiglitazone is active in vivo as an antidiabetic agent in the ob/ob mouse model, and has been used as an oral hypoglycemic agent in the treatment of type 2 diabetes in humans for many years.More related product prices
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