GRAMICIDIN C

CAS No.: 113-73-5

Chemical Name:: GRAMICIDIN C

Synonyms: GRAMICIDIN S;Gramicidin S-A;GRAMICIDIN C;Gramicidin S1;Soviet Gramicidin C;Cyclo(L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-);Cyclo(L-Leu-D-Phe-L-Pro-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Val-L-Orn-);HCO-X-GLY-L-ALA-D-LEU-L-ALA-D-VAL-L-VAL-D-VAL-L-TRP-D-LEU-L-PHE-D-LEU-L-TRP-D-LEU-L-TRP-NHCH2CH2OH

CBNumber:: CB6759311

Molecular Formula:: C60H92N12O10

Molecular Weight:: 1141.45

MOL File:: 113-73-5.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:14

Request For Quotation

GRAMICIDIN C Properties

Melting point	265-270 °C (decomp)(Solv: ethanol (64-17-5); ethyl ether (60-29-7))
Boiling point	827.42°C (rough estimate)
Density	1.0265 (rough estimate)
refractive index	1.6000 (estimate)
pka	13.00±0.70(Predicted)
form	Solid
color	White to off-white
Water Solubility	0.14g/L(28 ºC)
InChIKey	IUAYMJGZBVDSGL-XNNAEKOYSA-N

GRAMICIDIN C Chemical Properties,Uses,Production

Description

Gramicidin S was found in the culture broth of Bacillus brevis by Gause of the USSR Academy of Medical Sciences in 1944. It was later found by Otani of Osaka University in the cells of the Nagano strain of the same species. The antibiotic is a basic peptide showing strong activity against gram-positive bacteria and considerable activity against gramnegative cocci and Mycobacterium. Gramicidin S is rather toxic but is not absorbed orally; it is used topically as an ointment or as eye or ear drops in combination with other antibacterial drugs.

Definition

A cyclic peptide that acts on gram-positive bacteria.

Purification Methods

Gramicidin S crystallises from EtOH. The di-HCl crystallises from EtOH (+ few drops of HCl) with m 277-278o (see below). [NMR: Gibbons et al. Nature 227 840 1970, Beilstein 26 III/IV 4273.]

GRAMICIDIN C Preparation Products And Raw materials

Raw materials

Benzene Pentane Acetone Ethanol Trichloroethanol

Preparation Products

GRAMICIDIN C Suppliers

Global( 43)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21669	55	Inquiry
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	China	10312	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29825	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
Alfa Chemistry		United States	24072	58	Inquiry
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	China	3582	58	Inquiry
Zhejiang Hangyu API Co., Ltd	+8617531972939	China	2944	58	Inquiry

Supplier	Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
BOC Sciences	58
Henan Tianfu Chemical Co.,Ltd.	55
Shenzhen Nexconn Pharmatechs Ltd	58
career henan chemical co	58
Zhejiang J&C Biological Technology Co.,Limited	58
Alfa Chemistry	58
Hebei Miaoyin Technology Co.,Ltd	58
Zhejiang Hangyu API Co., Ltd	58

113-73-5(GRAMICIDIN C)Related Search:

Bacitracin GRAMICIDIN GRAMICIDIN GRAMICIDIN C

GRAMICIDIN C HCO-X-GLY-L-ALA-D-LEU-L-ALA-D-VAL-L-VAL-D-VAL-L-TRP-D-LEU-L-PHE-D-LEU-L-TRP-D-LEU-L-TRP-NHCH2CH2OH Cyclo(L-Leu-D-Phe-L-Pro-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Val-L-Orn-) Cyclo(L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-) Gramicidin S1 Soviet Gramicidin C GRAMICIDIN S Gramicidin S-A 113-73-5 C60H92N12O10