oxametacin

CAS No.: 27035-30-9

Chemical Name:: oxametacin

Synonyms: Flogar;ABC-8/3;oxametacin;Oxametacine;oxamethacin;Indoxamic acid;1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid;1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl-;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide

CBNumber:: CB6939025

Molecular Formula:: C19H17ClN2O4

Molecular Weight:: 372.806

MOL File:: 27035-30-9.mol

Modify Date:: 2024/10/23 13:36:13

Request For Quotation

oxametacin Properties

Melting point	181-182° (dec)
Density	1.2671 (rough estimate)
refractive index	1.6800 (estimate)
solubility	DMSO (Slightly), Methanol (Heated, Slightly)
form	Solid
pka	9.00±0.20(Predicted)
color	Crystals from dioxane

SAFETY

Risk and Safety Statements

Toxicity	LD50 orally in rats: 96 mg/kg (De Martiis, U.S. patent)

oxametacin Chemical Properties,Uses,Production

Description

Oxametacine is prepared by the acylation of hydroxylamine with indomethacin acid chloride. Oxametacine at a dose of 100 mg is reported to be as effective as 50 mg of indomethacin in reducing pain and inflammation with a lower incidence of adverse effects.

Definition

ChEBI: A hydroxamic acid obtained by formal condensation of the carboxy group of indometacin with the amino group of hydroxylamine.

Trade name

Flogar (UCB, Belgium; ABC, Portugal).

Safety Profile

Poison by ingestion and intraperitoneal routes. An anti-inflammatory agent. When heated to decomposition it emits toxic fumes of Clí and NOx.

oxametacin Preparation Products And Raw materials

Raw materials

Thionyl chloride Hydroxylamine hydrochloride Indometacin

Preparation Products

oxametacin Suppliers

Global( 10)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32202	58	Inquiry
TargetMol Chemicals Inc.	+8613564774135	United States	19889	58	Inquiry
Merck KGaA	21-20338288	China	292394	58	Inquiry
TargetMol Chemicals Inc.	15002134094	China	19746	58	Inquiry
Shanghai New Union Textra Import & Export Co., Ltd	+861-348-227-9455	China	2748	60	Inquiry
CHEMICAL LAND21	82- 2 -783 - 8063	South Korea	6303	74	Inquiry
Lanospharma Laboratories Co.,Ltd	13440048448	China	6329	56	Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd.	15800340161	CHINA	6650	58	Inquiry
United States Biological	800.520.3011 or 781.639.5092	United States	6214	80	Inquiry

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Merck KGaA	58
TargetMol Chemicals Inc.	58
Shanghai New Union Textra Import & Export Co., Ltd	60
CHEMICAL LAND21	74
Lanospharma Laboratories Co.,Ltd	56
Shanghai Hao Zhun Biological Technology Co., Ltd.	58
United States Biological	80

27035-30-9(oxametacin )Related Search:

Acetohydroxamic acid Deboxamet 2-(1-BENZYL-1H-INDOL-3-YL)-ETHYLAMINE 2-(5-METHOXY-1H-INDOL-3-YL)-ACETAMIDE CHEMBRDG-BB 5102396

Benanserine 1-Ethyl-5-methoxyindole N-ACETYL-5-HYDROXYTRYPTAMINE 2-METHYL-5-HYDROXYTRYPTAMINE 1-Acetyl-5-methoxyindole

N-ACETYL-6-METHOXYTRYPTAMINE 5-Methoxytryptamine Serotonin hydrochloride 5-HYDROXYINDOLE-3-ACETAMIDE oxametacin

chevron_left

1of3

chevron_right

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]-N-hydroxy-acetamide 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetohydroxamic acid ABC-8/3 Flogar Indoxamic acid oxametacin oxamethacin Oxametacine 1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl- 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-hydroxyacetamide 27035-30-9