3'-Hydroxypropiophenone
- CAS No.
- 13103-80-5
- Chemical Name:
- 3'-Hydroxypropiophenone
- Synonyms
- Ephedrine Impurity 7;3'-HYDROXYPROPIOPHENONE;3-HYDROXY PROPIOPHENONE;3'-Hydroxypropiophenone;1-(3-hydroxyphenyl)propan-1-one;1-Propanone,1-(3-hydroxyphenyl)-;Metaraminol bitartrate Impurity 44;Metaraminol Bitartrate Impurity 13
- CBNumber:
- CB7263985
- Molecular Formula:
- C9H10O2
- Molecular Weight:
- 150.17
- MOL File:
- 13103-80-5.mol
- Modify Date:
- 2023/5/15 10:43:54
| Melting point | 82 °C |
|---|---|
| Boiling point | 288.9±23.0 °C(Predicted) |
| Density | 1.104±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.09±0.10(Predicted) |
| color | Off-White to Beige |
| CAS DataBase Reference | 13103-80-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 2914500090 |
3'-Hydroxypropiophenone Chemical Properties,Uses,Production
Uses
1-?(3-?Hydroxyphenyl)?-?1-?propanone is a reactant used to synthesize tricyclic fused pyridines, a family of alkaloids with antimalarial activity.
Preparation
Preparation by diazotization of m-aminopropiophenone, followed by decomposition of the diazonium salt obtained, (71%)
Also obtained by saponification of 3-acetoxypropiophenone (b.p.2 127–128°) with refluxing 10% sodium hydroxide for 2–3 h (83%)
Also obtained by reductive deamination of 2-amino-5-hydroxypropiophenone (diazotization, followed by decomposition of the diazonium salt formed with copper powder in ethanol)
Also obtained by reaction of ethylmagnesium bromide with 3-hydroxy-N, N-diethylbenzamide in refluxing n-butyl ether for 4 h (75%)
Also obtained by treatment of 3-methoxypropiophenone (b.p.0.05 70–76°) with pyridinium chloride at 210° for 30 min (85%)
Also obtained by treatment of 1-hydroxy-1-(3-hydroxyphenyl)propane (m.p. 105–107°) with DDQ in dioxane for 72 h (97%).
3'-Hydroxypropiophenone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| WANKSONS CHEMICAL INDUSTRIES PVT LTD | +91-9769009151 +91-9769009151 | Mumbai, India | 44 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Clarion Drugs Ltd | +91-7122552671 +91-7122552671 | Maharashtra, India | 49 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Jayaveda Globaline LLP | 08069013892Ext 141 | Mumbai, India | 13 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| WANKSONS CHEMICAL INDUSTRIES PVT LTD | 58 |
| JSK Chemicals | 58 |
| Clarion Drugs Ltd | 58 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| CHEMSWORTH | 30 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
| Jayaveda Globaline LLP | 58 |
| Triveni chemicals | 58 |
| Pharma Affiliates | 58 |