Mafenide acetate
![Mafenide acetate Structure](CAS/GIF/13009-99-9.gif)
- CAS No.
- 13009-99-9
- Chemical Name:
- Mafenide acetate
- Synonyms
- Mefamide;mafatate;MARFANIL;MAFENIDE;maphenideacetate;MAFENIDE ACETATE;Sulfamylon Acetate;Mafenidine Acetate;MAFENAMIDE ACETATE;Sulfamimeron acetate
- CBNumber:
- CB7750274
- Molecular Formula:
- C9H14N2O4S
- Molecular Weight:
- 246.28
- MOL File:
- 13009-99-9.mol
- Modify Date:
- 2023/7/21 19:01:50
Melting point | 151-152°C |
---|---|
storage temp. | Inert atmosphere,2-8°C |
solubility | DMSO: soluble1mg/mL |
form | Solid |
color | white |
CAS DataBase Reference | 13009-99-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H332-H335 |
Precautionary statements | P261-P280-P305+P351+P338 |
WGK Germany | 3 |
HazardClass | IRRITANT |
HS Code | 2935904000 |
Toxicity | LD50 in rats, mice (mg/kg): 2040, 1580 i.v. (Skulan, Hoppe) |
Mafenide acetate Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
General Description
4-(Aminomethyl)benzenesulfonamide acetate (Sulfamylon)is a homologue of the sulfanilamide molecule. It is not atrue sulfanilamide-type compound, as it is not inhibited byPABA. Its antibacterial action involves a mechanism thatdiffers from that of true sulfanilamide-type compounds.
This compound is particularly effective against Clostridiumwelchii in topical application and was used duringWorld War II by the German army for prophylaxis ofwounds. It is not effective orally. It is currently used aloneor with antibiotics in the treatment of slow-healing, infectedwounds.
Some patients treated for burns with large quantities ofthis drug have developed metabolic acidosis. To overcomethis adverse effect, a series of new organic salts was prepared. The acetate in an ointment base proved to be themost efficacious.
Mafenide acetate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Apicore Pharmaceuticals Pvt Ltd | +91-2662267177 +91-2662267166 | Gujarat, India | 181 | 58 | Inquiry |
MYLAN API US LLC | 080 6672 8000 | New Delhi, India | 44 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
Shanghai Longyu Biotechnology Co., Ltd. | +8613917842738 | China | 2534 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
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