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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Chloropyrimidine >2,5-Dichloropyrimidine

2,5-Dichloropyrimidine

2,5-Dichloropyrimidine Structure
CAS No.
22536-67-0
Chemical Name:
2,5-Dichloropyrimidine
Synonyms
EOS-60492;2,5-Dichlo;2,5-chloropyrimidine;2,5-DICHLOROPYRIMIDINE;Macitentan Impurity 32;2,5‐Dichloropyridimidine;2,5-Dichloro-1,3-diazine;Pyrimidine, 2,5-dichloro-;2,5-Dichloropyrimidine>2,5-Dichloropyrimidine 97%
CBNumber:
CB7750461
Molecular Formula:
C4H2Cl2N2
Molecular Weight:
148.98
MOL File:
22536-67-0.mol
MSDS File:
SDS
Modify Date:
2024/4/26 17:21:34
Request For Quotation

2,5-Dichloropyrimidine Properties

Melting point 48-55 °C
Boiling point 190°C
Density 1.493
Flash point 140°C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka -2.84±0.22(Predicted)
form Powder
color Off-white
Water Solubility Slightly soluble in water.
λmax 268nm(EtOH)(lit.)
InChI InChI=1S/C4H2Cl2N2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey CEJAHXLRNZJPQH-UHFFFAOYSA-N
SMILES C1(Cl)=NC=C(Cl)C=N1
CAS DataBase Reference 22536-67-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H318-H400
Precautionary statements  P273-P280-P301+P312+P330-P305+P351+P338+P310
Hazard Codes  C,N,Xn
Risk Statements  22-41-50
Safety Statements  26-39-61
RIDADR  UN 3077 9/PG 3
WGK Germany  2
HazardClass  LACHRYMATOR, CORROSIVE
HazardClass  9
PackingGroup  Ⅲ
HS Code  29335990
NFPA 704
1
2 0

2,5-Dichloropyrimidine price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 720917 2,5-Dichloropyrimidine 97% 22536-67-0 1G ₹8757.43 2022-06-14 Buy
TCI Chemicals (India) D4045 2,5-Dichloropyrimidine min. 98.0 % 22536-67-0 5G ₹3000 2022-05-26 Buy
ALFA India ALF-H64066-22 2,5-Dichloropyrimidine, 95% 22536-67-0 100g ₹95829 2022-05-26 Buy
TCI Chemicals (India) D4045 2,5-Dichloropyrimidine min. 98.0 % 22536-67-0 25G ₹9300 2022-05-26 Buy
ALFA India ALF-H64066-14 2,5-Dichloropyrimidine, 95% 22536-67-0 25g ₹12412 2022-05-26 Buy
Product number Packaging Price Buy
720917 1G ₹8757.43 Buy
D4045 5G ₹3000 Buy
ALF-H64066-22 100g ₹95829 Buy
D4045 25G ₹9300 Buy
ALF-H64066-14 25g ₹12412 Buy

2,5-Dichloropyrimidine Chemical Properties,Uses,Production

Uses

2,5-Dichloropyrimidine acid is employed as a important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Preparation

2,5-Dichloropyrimidine was synthesised from 2-hydroxypyrimidine hydrochloride by treatment with aqueous chlorine solution. Reaction of the product with phosphoryl chloride in the presence of N,N-dimethylaniline gave the desired product in 40% yield. The sample was then purified by sublimation.

storage

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

structure and hydrogen bonding

C4H2Cl2N2, M=148.98 monoclinic, space group P21/m with a=6.077(3), b=19.771(8), c=7.399(3) ?, β=101.23(6)°, U=872 ?3 [from 2θ values of 29 reflections measured at±ω, 25 ≤2θ ≤ 38°, λ = 0.710 73?, T=150.0 K], Dcalc=1.702 g cm-3, Z=6, μ =0.993 mm-1[1].

References

[1] Blake A, et al. Structure Analysis Restrained by ab Initio Calculations: The Molecular Structure of 2,5-Dichloropyrimidine in Gaseous and Crystalline Phases. The Journal of Physical Chemistry, 1996; 100: 12280–12287.

2,5-Dichloropyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

tert-Butyl 4-(5-chloropyrimidin-2-yl)piperazine-1-carboxylate 2,5-Dichloro-4-iodopyrimidine 5-chloro-2-methoxy-pyrimidine 2(1H)-Pyrimidinethione, 5-chloro- (9CI)

2,5-Dichloropyrimidine Suppliers

Global( 313)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
SCINTELLI +91 8008555380 Hyderabad, India 25 58 Inquiry
HEMANT BIOSCIENCE 9848655224 Telangana, India 40 58 Inquiry
Vihita Chem Private Limited +91-9512002673 +91-9512002673 Gujarat, India 122 58 Inquiry
Ganapa Liife Science +91 7760536535 Bangalore, India 168 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4223 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Supplier Advantage
SCINTELLI 58
HEMANT BIOSCIENCE 58
Vihita Chem Private Limited 58
Ganapa Liife Science 58
JSK Chemicals 58
Reax Chemicals 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
TCI Chemicals (India) Pvt. Ltd. 58
Alfa Aesar 58

2,5-Dichloropyrimidine Spectrum

2,5-Dichloropyrimidine(22536-67-0)1HNMR

22536-67-0(2,5-Dichloropyrimidine)Related Search:

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2-4-DICHLOROPYRIMIDINE CRYSTALLINE,2,4-DICHLOROPYRIMIDINE,2,4-Dichloropyrimidine, GC 97%,2,4-Dichloropyrimidine, 98+% 2-Amino-5-bromo-4,6-dichloropyrimidine 97%,2-Amino-5-bromo-4,6-dichloropyrimidine97% 2-Chloromethyl-4,6-dichloropyrimidine 5-Bromo-2,4-dichloropyrimidine ,97%,5-BROMO-2,4-DICHLOROPYRIMIDINE 99% 2,4-Dichloropyrimidine-5-carboxylic acid
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2,5-DICHLOROPYRIMIDINE Pyrimidine, 2,5-dichloro- (7CI,8CI,9CI) 2,5-DICHLOROPYRIMIDINE,PURITY:95% MIN(HPLC) Pyrimidine, 2,5-dichloro- 2,5-chloropyrimidine 2,5-DichloropyriMidine 97+% 2,5-Dichloro-1,3-diazine 2,5-DichloropyriMidine 97+%, 5-DichloropyriMidine 97+% 2,5-Dichloropyrimidine 97% EOS-60492 2,5‐Dichloropyridimidine 2,5-Dichlo 2,5-DICHLOROPYRIMIDINE,PURITY Macitentan Impurity 32 2,5-Dichloropyrimidine> 22536-67-0 84-73-3 22536-60-0 Heterocycle-Pyrimidine series Building Blocks C4 to C5 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Pyrimidines Chlorinated heterocyclic series PYRIMIDINE Pyrimidine Series Pyridines, Pyrimidines, Purines and Pteredines