ChemicalBook > Product Catalog >Biochemical Engineering >Biochemical Reagents >GSK215

GSK215

CAS No.: 2743427-26-9

Chemical Name:: GSK215

Synonyms: GSK215;(2S,4R)-4-hydroxy-1-((S)-2-(2-(4-(3-methoxy-4-((4-((2-(methylcarbamoyl)phenyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)phenyl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide

CBNumber:: CB810705803

Molecular Formula:: C50H59F3N10O6S

Molecular Weight:: 985.14

MOL File:: 2743427-26-9.mol

Modify Date:: 2024/7/2 8:55:17

Request For Quotation

GSK215 Properties

Boiling point	1103.2±65.0 °C(Predicted)
Density	1.317±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 250 mg/mL (253.77 mM; Need ultrasonic)
form	Solid
pka	13.97±0.40(Predicted)
color	Off-white to light yellow
InChIKey	ZGSWGXNEXAXEGV-VSAGVCMVNA-N

GSK215 Chemical Properties,Uses,Production

in vitro

GSK215 (0.1-1000 nM; 2 h) effectively increases the FAK degradation by >90% and determines a DC50 of 1.3 nM in A549 cells. Its induced degradation is proteasome and ubiquitin-dependent. GSK215 (above 100 nM, 6h) primarily reduces kinases CDK7, RPS6KA3, MET, and GAK. This compound (100 nM, 48 h) inhibits migration, invasion, and collagen deposition in A549 cells.

GSK215 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK215 Suppliers

Global( 39)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Hubei Chuchang Biotech Co., Ltd.	+undefined15623860702	China	111	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3136	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	China	5225	58	Inquiry
InvivoChem	13549236410	China	6755	58	Inquiry
Shanghai Easy CDMO Co.,Ltd	021-61734564	China	10010	58	Inquiry
TargetMol Chemicals Inc.	15002134094	China	28070	58	Inquiry
Hubei Kele Fine Chemical Co., Ltd	027-59101668 19945030958	China	7969	58	Inquiry

Supplier	Advantage
Hubei Chuchang Biotech Co., Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58
Nantong HI-FUTURE Biology Co., Ltd.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
InvivoChem	58
Shanghai Easy CDMO Co.,Ltd	58
TargetMol Chemicals Inc.	58
Hubei Kele Fine Chemical Co., Ltd	58

2743427-26-9(GSK215)Related Search:

GSK 2033 2-((4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide GSK-2256098 GSK2837808A

GSK6853 GSK-A1 S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide GSK864 GSK484

GSK J4 HCl GSK 2334470 GSK2982772 GSK2636771 Benzeneacetamide, α-[[6-(4-amino-1-piperidinyl)-3,5-dicyano-4-ethyl-2-pyridinyl]thio]-

GSK778 N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide

chevron_left

1of4

chevron_right

GSK215 (2S,4R)-4-hydroxy-1-((S)-2-(2-(4-(3-methoxy-4-((4-((2-(methylcarbamoyl)phenyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)phenyl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide 2743427-26-9 C50H59F3N10O6S