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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >PDK-1 inhibitors >GSK 2334470

GSK 2334470

GSK 2334470 Structure
CAS No.
1227911-45-6
Chemical Name:
GSK 2334470
Synonyms
CS-1873;GSK 2334470;GSK 2334470 USP/EP/BP;GSK2334470 GSK-2334470;PDK1 inhibitor GS2334470;GSK2334470;GSK 2334470;GSK-2334470;1S,4R)-3-(6-(3-AMINO-1H-INDAZOL-6-YL)-2-(METHYLAMINO)PYRIMIDIN-4-YL)-N-CYCLOHEXYL-4-METHYLCYCLOHEXAN;1S,4R)-3-(6-(3-aMino-1H-indazol-6-yl)-2-(MethylaMino)pyriMidin-4-yl)-N-cyclohexyl-4-MethylcyclohexanecarboxaMide;(3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide;((3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-6-methylpiperidin-3-yl)(piperidin-1-yl)methanone
CBNumber:
CB62596521
Molecular Formula:
C25H34N8O
Molecular Weight:
462.59
MOL File:
1227911-45-6.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

GSK 2334470 Properties

Density 1.30±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: ≥10mg/mL
pka 12.84±0.40(Predicted)
form powder
color white to light brown
Stability Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

SAFETY

Risk and Safety Statements

WGK Germany  3

GSK 2334470 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML0217 GSK2334470 ≥98% (HPLC) 1227911-45-6 5MG ₹16672.2 2022-06-14 Buy
Sigma-Aldrich(India) SML0217 GSK2334470 ≥98% (HPLC) 1227911-45-6 25MG ₹67099.5 2022-06-14 Buy
Product number Packaging Price Buy
SML0217 5MG ₹16672.2 Buy
SML0217 25MG ₹67099.5 Buy

GSK 2334470 Chemical Properties,Uses,Production

Uses

GSK2334470 has been used as an inhibitor of 3-phosphoinositide dependent protein kinase-1 (PDK-1) in:

  • Treg cells, to identify regulators of interleukin 2 (IL-2)– signal transducer and activator of transcription 5 (STAT5) signaling
  • glycodelin-transfected HEC-1B human endometrial adenocarcinoma cells.
  • HeLa and Hs578T cells to test its effect on formylglycinamidine ribonucleotide synthase?(FGAMS) assembly

Biochem/physiol Actions

GSK2334470 (GSK-470) mediates cell cycle arrest. It also inhibits cellular proliferation and induces apoptosis in cancer cells.

GSK 2334470 Preparation Products And Raw materials

Raw materials

Preparation Products

GSK 2334470 Suppliers

Global( 107)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Nanjing Bicbiotechnology Co., Ltd +86-2552131256 +86-18251840740 China 6000 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Supplier Advantage
A.J Chemicals 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Nantong HI-FUTURE Biology Co., Ltd. 58
LEAPCHEM CO., LTD. 58
Nanjing Bicbiotechnology Co., Ltd 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58

GSK 2334470 Spectrum

GSK 2334470(1227911-45-6)1HNMR

1227911-45-6(GSK 2334470)Related Search:

S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide GSK864 GSK484 GSK J4 HCl GSK2982772
GSK2636771 Benzeneacetamide, α-[[6-(4-amino-1-piperidinyl)-3,5-dicyano-4-ethyl-2-pyridinyl]thio]- GSK778 N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide Sunitinib Malate
17-AAG Brefeldin A SU 4312 Bortezomib Y27632 (hydrochloride)
MK-1775 Axitinib Pictilisib
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GSK 2334470 1S,4R)-3-(6-(3-aMino-1H-indazol-6-yl)-2-(MethylaMino)pyriMidin-4-yl)-N-cyclohexyl-4-MethylcyclohexanecarboxaMide (3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide 3-Piperidinecarboxamide, 1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-, (3S,6R)- (3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide GSK 2334470 GSK2334470;GSK 2334470;GSK-2334470 ((3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-6-methylpiperidin-3-yl)(piperidin-1-yl)methanone 1S,4R)-3-(6-(3-AMINO-1H-INDAZOL-6-YL)-2-(METHYLAMINO)PYRIMIDIN-4-YL)-N-CYCLOHEXYL-4-METHYLCYCLOHEXAN PDK1 inhibitor GS2334470 CS-1873 GSK 2334470 USP/EP/BP GSK2334470 GSK-2334470 1227911-45-6 C25H34N8O Inhibitors Akt mTOR PI3K PI3K/Akt/mTOR API