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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

CAS No.: 179688-26-7

Chemical Name:: Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate

Synonyms: ERLOTINIBIM-B;ERLOTINIBINT-C;Erlotinib Impurity 6;Erlotinib interMidiate III;Erlotinib Hydrochloride iMpurity 25;Ethyl 4,5-Bis(2-Methoxyethoxy)-2-Nitrobe;4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;Methyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate;4,5-Bis(2-methoxyethoxy)-2-nitrobenzoic acid ethyl ester

CBNumber:: CB81504004

Molecular Formula:: C15H21NO8

Molecular Weight:: 343.33

MOL File:: 179688-26-7.mol

Modify Date:: 2023/4/23 13:52:06

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Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Properties

Boiling point	467.8±45.0 °C(Predicted)
Density	1.215
storage temp.	Refrigerator
solubility	DMSO (Slightly), Ethyl Acetate (Slightly)
form	Oil
color	Yellow
CAS DataBase Reference	179688-26-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319
Precautionary statements	P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Chemical Properties,Uses,Production

Uses

Ethyl 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate is used in the syntheses of 4-(indol-3-yl)quinazolines as epidermal growth factor receptor tyrosine kinase inhibitors. It is also used to prepare Erlotinib hydrochloride (E625000), a useful drug in treatment of non-?small-?cell lung cancer.

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Suppliers

Global( 119)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Raising Sun Pharma	+91-9399941155 +91-9399941155	Telangana, India	127	58	Inquiry
SL Drugs and Pharmaceuticals Pvt. Ltd.	+91 (40) 6661-1133	New Delhi, India	2688	50	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	China	2967	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry

Supplier	Advantage
Raising Sun Pharma	58
SL Drugs and Pharmaceuticals Pvt. Ltd.	50
A.J Chemicals	58
CHEMSWORTH	30
CLEARSYNTH LABS LTD.	58
SynZeal Research Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Capot Chemical Co.,Ltd.	60
Jinan Finer Chemical Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

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4,5-Bis(2-methoxyethoxy)-2-nitrobenzoic acid ethyl ester Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Methyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Erlotinib interMidiate III Benzoic acid,4,5-bis(2-Methoxyethoxy)-2-nitro-, ethyl ester Erlotinib Impurity 6 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate ###179688-26-7 ERLOTINIBINT-C ERLOTINIBIM-B Ethyl 4,5-Bis(2-Methoxyethoxy)-2-Nitrobe Erlotinib Hydrochloride iMpurity 25 179688-26-7 C15H21NO8 Erlotinib INTERMEDIATES