Ethyl pyruvate
- CAS No.
- 617-35-6
- Chemical Name:
- Ethyl pyruvate
- Synonyms
- ETHYL 2-OXOPROPANOATE;PYRUVIC ACID ETHYL ESTER;PAEE;Ethyl pyroracemate;ETHYL 2-OXOPROPIONATE;ETHYL 2-OXOPROPRIONATE;PYR ET;STEAROY;NSC 48386;FEMA 2457
- CBNumber:
- CB3198366
- Molecular Formula:
- C5H8O3
- Molecular Weight:
- 116.12
- MOL File:
- 617-35-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/9/24 16:40:18
| Melting point | -58 °C |
|---|---|
| Boiling point | 144 °C (lit.) |
| Density | 1.045 g/mL at 25 °C (lit.) |
| vapor pressure | 2.36hPa at 25℃ |
| FEMA | 2457 | ETHYL PYRUVATE |
| refractive index |
n |
| Flash point | 114 °F |
| storage temp. | Store at +2°C to +8°C. |
| solubility | 10g/l |
| form | Liquid |
| color | Clear pale yellow |
| Odor | at 10.00 % in dipropylene glycol. ether fruity sweet sharp rum vegetable caramel |
| Odor Type | ethereal |
| Water Solubility | Miscible with water, ethanol and ether. |
| Merck | 14,8021 |
| JECFA Number | 938 |
| BRN | 1071466 |
| Stability | Volatile |
| InChIKey | XXRCUYVCPSWGCC-UHFFFAOYSA-N |
| LogP | 0.435 at 22.5℃ |
| CAS DataBase Reference | 617-35-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Propanoic acid, 2-oxo-, ethyl ester(617-35-6) |
| EPA Substance Registry System | Propanoic acid, 2-oxo-, ethyl ester (617-35-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H314 | |||||||||
| Precautionary statements | P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,F | |||||||||
| Risk Statements | 10 | |||||||||
| Safety Statements | 16 | |||||||||
| RIDADR | UN 3272 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Flammable/Irritant | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29183000 | |||||||||
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rat > 2000 mg/kg | |||||||||
| NFPA 704 |
|
Ethyl pyruvate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W245735 | Ethyl pyruvate ≥97%, FG | 617-35-6 | 1SAMPLE-K | ₹5141.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W245735 | Ethyl pyruvate ≥97%, FG | 617-35-6 | 250G | ₹10067.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W245735 | Ethyl pyruvate ≥97%, FG | 617-35-6 | 1KG | ₹19853.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W245735 | Ethyl pyruvate ≥97%, FG | 617-35-6 | 10KG | ₹124963.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W245735 | Ethyl pyruvate ≥97%, FG | 617-35-6 | 25KG | ₹291982.73 | 2022-06-14 | Buy |
Ethyl pyruvate Chemical Properties,Uses,Production
Chemical Properties
Ethyl pyruvate has a vegetable, caramel odor.
Occurrence
Reported found in Parmesan cheese, cognac, grape wines, cocoa and mushrooms.
Uses
Ethyl pyruvate (EP) has demonstrated neuroprotective effects against acute brain injury through its anti-inflammatory action.
Preparation
By direct esterification of pyruvic acid with absolute ethyl alcohol at the boil and subsequent vacuum distillation; by esterification via oxidation of vapors of ethyl lactate in the presence of V2O5 at 155°C
General Description
Ethyl pyruvate is a volatile aliphatic ester of the pyruvate metabolite. It is present as a food additive/odor-active component in various food and beverage products. It is also used as an inhibitory odorant to repel the insects from human proximity.
Purification Methods
Shake the ester with 10mL portions of saturated aqueous CaCl2 solution (removes ethyl acetate) and the organic layer is removed by centrifugation, decantation and filtration, and is distilled under reduced pressure. Purification of small quantities is carried out via the bisulfite adduct: the ester (2.2mL) is shaken with saturated NaHSO3 (3.6mL), chilled in a freezing mixture when crystals separate rapidly (particularly if seeded). After 5minutes EtOH (10mL) is added and the crystals are filtered off, washed with EtOH and Et2O and dried. Yield ca 3g of bisulfite adduct. Then treat the adduct (16g) with saturated aqueous MgSO4 (32mL) and 40% formaldehyde (5mL) and shake, whereby the ester separates as an oil which is extracted with Et2O. The extract is dried (MgSO4), filtered, evaporated and the residue is distilled (b 56o/20mm), and then redistilled (b 147.5o/750mm) to give 5.5g of pure ester. [Cornforth Org Synth Coll Vol IV 467 1963, Beilstein 3 IV 1513.]
Ethyl pyruvate Preparation Products And Raw materials
Raw materials
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ANJI BIOSCIENCES | +91-9000100077 +91-9000100077 | Hyderabad, India | 430 | 58 | Inquiry |
| Nagar Haveli Perfumes & Aromatics | +917506551149 | Mumbai, India | 230 | 58 | Inquiry |
| INDIAN PLATINUM PRIVATE LIMITED | +91-9322395199 +91-9322395199 | Mumbai, India | 54 | 58 | Inquiry |
| Evans Fine Chem | +91-9821340302 +91-9821340302 | Maharashtra, India | 286 | 58 | Inquiry |
| Dhara Industries | +91-9322395199 +91-9322395199 | Mumbai, India | 190 | 58 | Inquiry |
| Dr Prem's Molecules Pvt. Ltd. | +91 9825310038 | New Delhi, India | 547 | 50 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ANJI BIOSCIENCES | 58 |
| Nagar Haveli Perfumes & Aromatics | 58 |
| INDIAN PLATINUM PRIVATE LIMITED | 58 |
| Evans Fine Chem | 58 |
| Dhara Industries | 58 |
| Dr Prem's Molecules Pvt. Ltd. | 50 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
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