TCPOBOP
- CAS No.
- 76150-91-9
- Chemical Name:
- TCPOBOP
- Synonyms
- TCPOBOP;3,3',5,5'-TETRACHLORIDE-BPB;TCPOBOP - CAS 76150-91-9 - Calbiochem;inhibit,Bcl-2 Family,TCPOBOP,Inhibitor;1,4-Bis(3,5-dichloro-2-pyridyloxy)benzene;1,4-BIS[2-(3,5-DICHLOROPYRIDYLOXY)]BENZENE;1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene;3,3',5,5'-TETRACHLORIDE-BISPYRIDYLOXYBENZENE;1,4-Bis[(3,5-dichloropyridin-2-yl)oxy]benzene;3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene
- CBNumber:
- CB8155924
- Molecular Formula:
- C16H8Cl4N2O2
- Molecular Weight:
- 402.06
- MOL File:
- 76150-91-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/20 16:43:00
| Boiling point | 444.8±45.0 °C(Predicted) |
|---|---|
| Density | 1.518±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >10 mg/mL |
| form | solid |
| pka | -0.52±0.10(Predicted) |
| color | white |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week. |
TCPOBOP price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T1443 | TCPOBOP ≥98% (HPLC), solid | 76150-91-9 | 5MG | ₹7555.85 | 2022-06-14 | Buy |
| Sigma-Aldrich | 580563 | TCPOBOP - CAS 76150-91-9 - Calbiochem The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents. | 76150-91-9 | 25MG | ₹22390 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 580563 | TCPOBOP - CAS 76150-91-9 - Calbiochem The most potent known member of the phenobarbital-like class of cytochrome P450 (CYP)-inducing agents. | 76150-91-9 | 25MG | ₹22390 | 2022-06-14 | Buy |
TCPOBOP Chemical Properties,Uses,Production
Uses
TCPOBOP is an agonist for mCAR, inducing cytochrome P450 monooxygenases and multidrug resistance and cenobiotic efflux proteins.
General Description
A highly potent inducer of phenobarbital-like class of cytochrome P450 (CYP) enzymes. A tumor promoter that induces hepatocyte proliferation, independent of the presence of cytokines or transcription factors. Activates orphan nuclear receptors mCAR (mouse constitutive androstane receptor) and hPXR (human pregane X receptor), but has little or no effect on hCAR and mPXR. Also suppresses the expression of multi-drug resistance genes mdr2 and mdr3 in mouse liver.
Biochem/physiol Actions
TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. The most potent known member of the phenobarbital-like class of CYP-inducing agents.
TCPOBOP Preparation Products And Raw materials
Raw materials
Preparation Products
TCPOBOP Suppliers
Global( 77)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | China | 25014 | 65 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48467 | 58 | Inquiry |
| YJ Pharma | 0513-15251351988 15251351988 | China | 372 | 58 | Inquiry |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | China | 63720 | 58 | Inquiry |
76150-91-9(TCPOBOP)Related Search:
3,3',5,5'-TETRACHLORIDE-BISPYRIDYLOXYBENZENE
3,3',5,5'-TETRACHLORIDE-BPB
1,4-BIS[2-(3,5-DICHLOROPYRIDYLOXY)]BENZENE
TCPOBOP
2,2’-(1,4-phenylenebis(oxy))bis(3,5-dichloro-pyridin
1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene, 3,3μ,5,5μ-Tetrachloro-1,4-bis(pyridyloxy)benzene
1,4-Bis(3,5-dichloro-2-pyridyloxy)benzene
1,4-Bis[(3,5-dichloropyridin-2-yl)oxy]benzene
2,2'-(4,1-Phenylenebisoxy)bis(3,5-dichloropyridine)
2,2'-(p-Phenylenebisoxy)bis(3,5-dichloropyridine)
2,2'-[Benzene-1,4-diylbis(oxy)]bis(3,5-dichloropyridine)
3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene
TCPOBOP - CAS 76150-91-9 - Calbiochem
1,4-Bis(3,5-Dichloro-2-pyridinyloxy)benzene
3,5-dichloro-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}pyridine
Pyridine, 2,2'-[1,4-phenylenebis(oxy)]bis[3,5-dichloro-
inhibit,Bcl-2 Family,TCPOBOP,Inhibitor
76150-91-9
C16H8N2O2Cl4
C16H8Cl4N2O2
Apoptosis and Cell Cycle
Cell Cycle Regulators
Cell Cycle
Cell Biology
Cell Signaling and Neuroscience
BioChemical