4-Chloro-3-(trifluoromethyl)phenyl isocyanate

CAS No.: 327-78-6

Chemical Name:: 4-Chloro-3-(trifluoromethyl)phenyl isocyanate

Synonyms: 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene;Sorafenib INT1;Sorafenib intermediate 3;4-chloro-a,a,a-trifluoro-M-tolyl ester;4-Chloro-α,α,α-trifluoro-m-tolyl isocyanate;4-CHLORO-3-TRIFLUROMETHYL)PHENYL ISOCYANATE;3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE;4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE;4-Chloro-3-(trifluoromethy) phenyl isocyanate;4-Chloro-3-(trifluoroMethoxy)phenyl Isocyanate

CBNumber:: CB8262374

Molecular Formula:: C8H3ClF3NO

Molecular Weight:: 221.56

MOL File:: 327-78-6.mol

MSDS File:: SDS

Modify Date:: 2024/1/18 17:03:10

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4-Chloro-3-(trifluoromethyl)phenyl isocyanate Properties

Melting point	40-42 °C(lit.)
Boiling point	86-90 °C14 mm Hg(lit.)
Density	1.4720 (estimate)
vapor pressure	91Pa at 20℃
Flash point	211 °F
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	soluble in Chloroform, Methanol
form	Low Melting Solid, Powder or Chunks
color	White to yellow
Sensitive	Moisture Sensitive
BRN	522032
InChI	InChI=1S/C8H3ClF3NO/c9-7-2-1-5(13-4-14)3-6(7)8(10,11)12/h1-3H
InChIKey	AHFPRSSHNSGRCU-UHFFFAOYSA-N
SMILES	C1(Cl)=CC=C(N=C=O)C=C1C(F)(F)F
CAS DataBase Reference	327-78-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07,GHS08

Signal word

Danger

Hazard statements

H302+H312+H332-H315-H317-H318-H334-H335

Precautionary statements

P261-P264-P280-P301+P312-P302+P352+P312-P305+P351+P338

Hazard Codes

Risk Statements

20/21/22-36/37-36/37/38-42-20/22

Safety Statements

7-26-27-37/39-36/37/39-45-23

RIDADR

UN 2206 6.1/PG 3

WGK Germany

Hazard Note

Harmful/Moisture Sensitive

HazardClass

6.1

PackingGroup

III

HS Code

29291090

NFPA 704

	1
4		1

4-Chloro-3-(trifluoromethyl)phenyl isocyanate price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	374881	4-Chloro-3-(trifluoromethyl)phenyl isocyanate 98%	327-78-6	5G	₹6148.6	2022-06-14	Buy
Sigma-Aldrich(India)	374881	4-Chloro-3-(trifluoromethyl)phenyl isocyanate 98%	327-78-6	5G	₹6148.6	2022-06-14	Buy
TCI Chemicals (India)	C2778	4-Chloro-3-(trifluoromethyl)phenyl Isocyanate min. 98.0 %	327-78-6	5G	₹6000	2022-05-26	Buy
TCI Chemicals (India)	C2778	4-Chloro-3-(trifluoromethyl)phenyl Isocyanate min. 98.0 %	327-78-6	25G	₹19900	2022-05-26	Buy

Product number	Packaging	Price	Buy
374881	5G	₹6148.6	Buy
374881	5G	₹6148.6	Buy
C2778	5G	₹6000	Buy
C2778	25G	₹19900	Buy

4-Chloro-3-(trifluoromethyl)phenyl isocyanate Chemical Properties,Uses,Production

Chemical Properties

White solid or melt

Uses

4-Chloro-3-(trifluoromethyl)phenyl isocyanate may be used in the synthesis of: N-(5′-deoxy-3′-O-tert-butyldimethylsilyl-β-D-thymidin-5′-yl)-N′-(4-chloro-3-trifluoromethylphenyl)-thiourea [1,3-bis(4-chloro-α,α,α-trifluoro-m-tolyl)urea] trans-1-(4-chloro-3-trifluoromethyl-phenyl)-3-(4-hydroxy-cyclohexyl)-urea

General Description

4-Chloro-3-(trifluoromethyl)phenyl isocyanate participates in an efficient methodology for the synthesis of 5-methyl-3-aryl-2-thiooxazolidin-4-ones.

4-Chloro-3-(trifluoromethyl)phenyl isocyanate Preparation Products And Raw materials

Raw materials

2-Chloro-5-nitrobenzotrifluoride 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine 2-Chlorobenzotrifluoride

Preparation Products

Regorafenib iMpurity Regorafenib Sorafenib

4-Chloro-3-(trifluoromethyl)phenyl isocyanate Suppliers

Global( 459)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Paushak Limited	+91-2653007932 +91-9727736899	Vadodara, India	59	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
AVIK PHARMACEUTICAL LIMITED	+91-22-67685000	New Delhi, India	54	58	Inquiry
Reax Chemicals	08048372701Ext 416	Hyderabad, India	4223	58	Inquiry
ChemOrbit International	91-40-23712139	Hyderabad, India	264	58	Inquiry
Merix Laboratories Pvt. Ltd	91-40-27842260	Hyderabad, India	132	58	Inquiry
ALTAIR ALCHEMY Laboratories	91--9014276848	Hyderabad, India	324	58	Inquiry

Supplier	Advantage
Paushak Limited	58
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
Alfa Aesar	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
AVIK PHARMACEUTICAL LIMITED	58
Reax Chemicals	58
ChemOrbit International	58
Merix Laboratories Pvt. Ltd	58
ALTAIR ALCHEMY Laboratories	58

4-Chloro-3-(trifluoromethyl)phenyl isocyanate Spectrum

4-Chloro-3-(trifluoromethyl)phenyl isocyanate(327-78-6)¹HNMR 4-Chloro-3-(trifluoromethyl)phenyl isocyanate(327-78-6)Raman 4-Chloro-3-(trifluoromethyl)phenyl isocyanate(327-78-6)IR

327-78-6(4-Chloro-3-(trifluoromethyl)phenyl isocyanate)Related Search:

Propyl isocyanate 4-Chlorobenzotrifluoride Benzotrifluoride 4-(Chloromethyl)benzoic acid 3-Fluorobenzotrifluoride

Vinylbenzyl chloride Phenyl butyrate Chlorosulfonyl isocyanate Diphenyl chlorophosphate Phenyl isothiocyanate

PHENYL ACETATE 2-Methylbenzotrifluoride Phenyl chloroformate 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine PHENYL VALERATE

Phenylhydrazine Trityl olmesartan Epichlorohydrin

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4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE 4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 98% 4-Chloro-α,α,α-trifluoro-m-tolyl isocyanate 4-Chloro-3-(trifluoromethyl)phenyl isocyanate,98% 4-Chloro-3-(trifluoroMethyl)phenyl isocyanate, 98% 5GR Benzene, 1-chloro-4-isocyanato-2-(trifluoromethyl)- 4-chloro-a,a,a-trifluoro-M-tolyl ester 4-Chloro-3-(trifluoroMethyl)phenyl isocyanate, 97.5% 4-Chloro-3-(trifluoroMethoxy)phenyl Isocyanate Three fluorine chlorine - 4-3 - Methyl phenyl isocyanate Sorafenib INT1 Isocyanic Acid 4-Chloro-3-(trifluoromethyl)phenyl Ester 4-CHLORO-3-TRIFLUROMETHYL)PHENYL ISOCYANATE 4-Chloro-3-(trifluoromethyl)phenyl isocyanate(327-78-6) 4-Chloro-3-(trifluoromethyl)phenyl Isocyanate > 4-Chloro-3-(trifluoromethy) phenyl isocyanate 1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene Phenyl 4- chloro -3- trifluoromethyl isocyanate Sorafenib intermediate 3 327-78-6 372-78-6 ClC6H3CF3NCO ARYL ISOCYANATE Building Blocks Organic Building Blocks Nitrogen Compounds Isocyanates Phenyl isocyanate&Phenyl isothiocyanate Isocyanates Nitrogen Compounds Organic Building Blocks