ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >DNA damage >PARP inhibitors >ME0328
ME0328
![ME0328 Structure](CAS/20181012/GIF/1445251-22-8.gif)
- CAS No.
- 1445251-22-8
- Chemical Name:
- ME0328
- Synonyms
- ME0328;ME0328 ME-0328;ME0328 USP/EP/BP;4-Dihydro-4-oxo-3;ME0328; ME 0328; ME-0328;4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide;(S)-3,4-Dihydro-4-oxo-N-(1-phenylethyl)-2-quinazolinepropanamide;2-Quinazolinepropanamide, 3,4-dihydro-4-oxo-N-[(1S)-1-phenylethyl]-;(S)-3-(4-Oxo-3,4-dihydroquinazolin-2-yl)-N-(1-phenylethyl)propanamide;3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
- CBNumber:
- CB82705099
- Molecular Formula:
- C19H19N3O2
- Molecular Weight:
- 321.37
- MOL File:
- 1445251-22-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:02:29
ME0328 Chemical Properties,Uses,Production
Description
The poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species. ME0328 is an inhibitor of PARP3 (IC50 = 0.89 μM), which is a regulator of DNA repair and mitotic progression. It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.
Uses
ME0328 is a potent poly ADP ribose polymerase (PARP) inhibitor with selectivity towards the human ADP-Ribosyltransferase ARTD3/PARP3.
ME0328 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 103)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
CR Corporation Limited | +8613062833949 | China | 8647 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | China | 6000 | 58 | Inquiry |
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ME0328
3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
(S)-3,4-Dihydro-4-oxo-N-(1-phenylethyl)-2-quinazolinepropanamide
ME0328; ME 0328; ME-0328
4-Dihydro-4-oxo-3
4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide
2-Quinazolinepropanamide, 3,4-dihydro-4-oxo-N-[(1S)-1-phenylethyl]-
ME0328 USP/EP/BP
ME0328 ME-0328
(S)-3-(4-Oxo-3,4-dihydroquinazolin-2-yl)-N-(1-phenylethyl)propanamide
1445251-22-8
Inhibitors