ME0328
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- ₹14807.4
- Product name: ME0328
- CAS: 1445251-22-8
- MF: C19H19N3O2
- MW: 321.37
- EINECS:808-923-8
- MDL Number:MFCD27991291
- Synonyms:ME0328;3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide;(S)-3,4-Dihydro-4-oxo-N-(1-phenylethyl)-2-quinazolinepropanamide;ME0328; ME 0328; ME-0328;4-Dihydro-4-oxo-3;4-Dihydro-4-oxo-N-[(1S)-1-phenylethyl]-2-quinazolinepropanamide;2-Quinazolinepropanamide, 3,4-dihydro-4-oxo-N-[(1S)-1-phenylethyl]-;ME0328 USP/EP/BP
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML0999
- Product descriptionME0328 ≥98% (HPLC)
- Packaging5MG
- Price₹14807.4
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML0999 | ME0328 ≥98% (HPLC) | 5MG | ₹14807.4 | 2022-06-14 | Buy |
Properties
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
The poly(ADP-ribose) polymerases (PARPs) are enzymes with roles in DNA repair, apoptosis, inflammation, and other cellular events, particularly in response to reactive oxygen and nitrogen species. ME0328 is an inhibitor of PARP3 (IC50 = 0.89 μM), which is a regulator of DNA repair and mitotic progression. It displays selectivity for PARP3 over 12 other PARP family members. ME0328 is cell permeable and elicits PARP3-specific effects at submicromolar concentrations.Related product price
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