Cyclosporin H

CAS No.: 83602-39-5

Chemical Name:: Cyclosporin H

Synonyms: CS-1741;CS-1030;Sandoz 37-839;CYCLOSPORIN H;CsH cyclosporin;Cyclosporin H, >=95%;Cyclosporin impurity H;Cyclosporine IMpurity-H;Cyclosporine Impurity 8;Cyclosporin H, EvoPure?

CBNumber:: CB8279114

Molecular Formula:: C62H111N11O12

Molecular Weight:: 1202.61

MOL File:: 83602-39-5.mol

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

Cyclosporin H Properties

Melting point	148-151°C
Boiling point	1293.8±65.0 °C(Predicted)
Density	1.016±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
pka	13.32±0.70(Predicted)
form	powder
color	white to beige
optical activity	[α]/D -100 to -115°, c = 0.5 in methanol

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H302-H350-H360

Precautionary statements

P202-P264-P270-P280-P301+P312-P308+P313

HS Code

29420000

NFPA 704

	0
2		0

Cyclosporin H price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML1575	Cyclosporin H ≥97% (HPLC)	83602-39-5	1MG	₹10954.9	2022-06-14	Buy
Sigma-Aldrich(India)	SML1575	Cyclosporin H ≥97% (HPLC)	83602-39-5	5MG	₹44057.75	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML1575	1MG	₹10954.9	Buy
SML1575	5MG	₹44057.75	Buy

Cyclosporin H Chemical Properties,Uses,Production

Description

Cyclosporin H is a natural cyclic undecapeptide that selectively antagonizes the formyl peptide receptor at concentrations ranging from 0.1 to 10 μM. Unlike cyclosporin A , cyclosporin H does not bind cyclophilin to evoke an immunosuppressant response. Cyclosporin H has been reported to inhibit phorbol ester-mediated effects in mouse skin and block calcium/calmodulin-dependent EF-2 phosphorylation in vitro.

Chemical Properties

White Powder

Uses

Cyclosporin H is a minor analogue of the cyclosporin family which is immunologically inactive as it does not bind to immunophilin. Cyclopsorin H is the most extensively investigated of the minor cyclosporin analogues and displays a range of activities. It is a potent inhibitor of tumour-promoting phorbol esters on mouse skin in vivo, and of calcium/calmodulin-dependent EF-2 phosphorylation in vitro, a potent and selective antagonist of formyl peptide receptor and inhibitor of formyl peptide-induced superoxide formation.

Cyclosporin H Preparation Products And Raw materials

Raw materials

Preparation Products

Cyclosporin H Suppliers

Global( 169)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Shenzhen Excellent Biomedical Technology Co.,Ltd.	+86-0755-26050679 +86-15915472436	China	1031	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9338	55	Inquiry
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	China	3000	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
SIMAGCHEM CORP	+86-13806087780	China	17367	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
SynZeal Research Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
Shenzhen Excellent Biomedical Technology Co.,Ltd.	58
LEAP CHEM CO., LTD.	58
Hangzhou FandaChem Co.,Ltd.	55
Shaanxi Pioneer Biotech Co., Ltd .	58
BOC Sciences	58
SIMAGCHEM CORP	58

83602-39-5(Cyclosporin H)Related Search:

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CYCLOSPORIN H Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] 5-(N-Methyl-D-valine)cyclosporin A Cyclo[L-alanyl-D-alanyl-N-Methyl-L- leucyl-N-Methyl-L-leucyl-N-Methyl-D-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-diMethyl-L-2-aMinooctanoyl-L-2-aMinobutanoyl-N-Methylglycyl-N-Methyl-L-leucyl-L-valyl-N-Methyl-L-leucyl] Sandoz 37-839 Cyclosporin H, >=95% Cyclosporine IMpurity-H 5-(N-Methyl-D-valine)cyclosporine A Cyclosporin H, froM MicroMonospora Cyclosporin H/Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl] CS-1741 CS-1030 Cyclosporin H, 95%, from Micromonospora Cyclosporin Impurity 8(Cyclosporin H) Cyclosporin A, 5-(N-methyl-D-valine)- Cyclosporine Impurity 8 (3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-((1R,2R,E)-1-hydroxy-2-methylhex-4-en-1-yl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone Cyclosporin Impurity HQ: What is Cyclosporin Impurity H Q: What is the CAS Number of Cyclosporin Impurity H Q: What is the storage condition of Cyclosporin Impurity H Q: What are the applications of Cyclosporin Impurity H Cyclosporin impurity H Cyclosporin H, EvoPure? CsH cyclosporin 83602-39-5 C62H111N11O12 Intermediates & Fine Chemicals Peptides Pharmaceuticals ACTIVE PHARMACEUTICAL INGREDIENTS