ChemicalBook > Product Catalog >Analytical Chemistry >Analysis reagents >Ion chromatography reagents >Fenofibric acid
Fenofibric acid
- CAS No.
- 42017-89-0
- Chemical Name:
- Fenofibric acid
- Synonyms
- FENOFIBRATE ACID;lf153;A-1081;FNF Acid;alpha1081;lf178acid;NSC 281318;EP-B/USP RC B;FENOFIBRIC ACID;FeNAfibric acid
- CBNumber:
- CB8400259
- Molecular Formula:
- C17H15ClO4
- Molecular Weight:
- 318.75
- MOL File:
- 42017-89-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/1/27 9:38:02
| Melting point | 177-179°C |
|---|---|
| Boiling point | 486.5±35.0 °C(Predicted) |
| Density | 1.286±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 3.09±0.10(Predicted) |
| form | powder |
| color | White to Off-White |
| BRN | 2058973 |
| InChI | InChI=1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21) |
| InChIKey | MQOBSOSZFYZQOK-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C(OC1=CC=C(C(=O)C2=CC=C(Cl)C=C2)C=C1)(C)C |
| CAS DataBase Reference | 42017-89-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H410 | |||||||||
| Precautionary statements | P264-P270-P273-P301+P312-P391-P501 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 36/37/38-50/53-22 | |||||||||
| Safety Statements | 26-36/37/39-61-60-24/25 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UA2453000 | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29189900 | |||||||||
| Toxicity | LD50 oral in rat: 1242mg/kg | |||||||||
| NFPA 704 |
|
Fenofibric acid price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR3315 | Fenofibrate Related Compound B certified reference material, pharmaceutical secondary standard | 42017-89-0 | 50MG | ₹51635.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 90568 | Fenofibric acid analytical standard | 42017-89-0 | 10MG | ₹9959 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 796565 | 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid 95% | 42017-89-0 | 1G | ₹4979.5 | 2022-06-14 | Buy |
| TCI Chemicals (India) | F1011 | Fenofibric Acid min. 98.0 % | 42017-89-0 | 1G | ₹5300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | F1011 | Fenofibric Acid min. 98.0 % | 42017-89-0 | 5G | ₹10100 | 2022-05-26 | Buy |
Fenofibric acid Chemical Properties,Uses,Production
Chemical Properties
Fenofibric acid is a white to almost white crystalline powder that is stable under ordinary conditions and has a melting point of 179 – 183°C. Its empirical formula is C17H15ClO4 and molecular weight 318.75. Fenofibric acid is insoluble in water; its solubility increases with pH in buffered media.
Uses
Fenofibric acid, the active metabolite of fenofibrate. Increases Apolipoprotein A-Iediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptorependent manner
Definition
ChEBI: A monocarboxylic acid that is 2-methylpropanoic acid substituted by a 4-(4-chlorobenzoyl)phenoxy group at position 2. It is a metabolite of the drug fenofibrate.
Metabolism
Fenofibric acid is primarily conjugated with glucuronic acid and then excreted in urine. A small amount of fenofibric acid is reduced at the carbonyl moiety to a benzhydrol metabolite, which is, in turn, conjugated with glucuronic acid and excreted in urine. In vitro and in vivo metabolism data indicate that fenofibric acid does not undergo oxidative metabolism (e.g. cytochrome P450) to a significant extent. The enzymes CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4 do not play a role in the metabolism of fenofibric acid.
Fenofibric acid Preparation Products And Raw materials
Raw materials
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| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Vihita Chem Private Limited | +91-9512002673 +91-9512002673 | Gujarat, India | 122 | 58 | Inquiry |
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| Harman Finochem Ltd | +91-2226528080 +91-2226528080 | Maharashtra, India | 37 | 58 | Inquiry |
| Ebenezer Industries | Gujarat, India | 96 | 58 | Inquiry | |
| Om Pharmaceutical Industries | +91-2502344639 +91-9822376539 | Maharashtra, India | 32 | 58 | Inquiry |
42017-89-0(Fenofibric acid)Related Search:
(4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone
(Fenofibrate IMpurity)
FENOFIBRATE RELATED COMPOUND C (25 MG) (1-METHYLETHYL 2-[[2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOYL]OXY]-2-METHYLPROPANOATE)
Ethyl 2-(Chlorosulfonyl)acetate
Dimethyldimethoxysilane
Methyltriethoxysilane
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2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOIC ACID
LABOTEST-BB LT00239222
FENOFIBRIC ACID
SALOR-INT L498335-1EA
2-[4-(4-CHLORO-BENZOYL)-PHENOXY]-2-METHYL-PROPIONIC ACID (FENOFIBRIC ACID)
2-[4-(4-CHLOROBENBONYZOYL)PHENOXY)-2-METHYLPROPIONIC ACID
2-[4'-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid
A-1081
Fenofibrate Related Compound B (25 mg) (2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic acid)
alpha1081
2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-propanoicaci
FeNAfibric acid
Fenofibrate EP IMpurity B
2-(4-(4-Chlorobenzoyl)phenoxy)-2-Methylpropanoic acid, 95+%
FNF Acid
NSC 281318
Fenofibric acid, >=99%
2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid 95%
lf153
lf178acid
procetofenicacid
2-[4-(4-CHLORO-BENZOYL)-PHENOXY]-2-METHYL-PROPIONIC ACID
2-[4-(4-CHLOROBENZOYL) PHENOXY]-2'-METHYL PROPANOIC ACID
Fenofibrate Impurity Ⅱ:Fenofibric acid(2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionic acid)
FenofibricAcid>
Fenofibrate impurity B CRS
Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-
Fenofibrate EP Impurity B (Fenofibric Acid)
Fenofibrate USP Related
Compound B
Fenofibrate EP Impurity B/ Fenofibrate Related Compound B (Fenofibric Acid)
Fenofibric acid D4
Fenofibric AcidQ: What is
Fenofibric Acid Q: What is the CAS Number of
Fenofibric Acid Q: What is the storage condition of
Fenofibric Acid Q: What are the applications of
Fenofibric Acid
Fenofibrate impurity B (F0048010)
Fenofibrate Related Compound B (2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic acid) (1269618)
Choline Fenofibrate Impurity B
Fenofibrate Impurity 2(Fenofibrate EP Impurity B)
Fenofibrate impurity B (EP)
2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoate
FENOFIBRATE ACID
Choline Fenofibrate EP Impurity B
Fenofibric acid,2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid
EP-B/USP RC B
Fenofibric acid 100 μg/ml Acetone
Fenofibrate Related Compound II（2-[4-（4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic Acid (Fenofibric Acid)
Fenofibric acid, 10 mM in DMSO
42017-89-0
C20H21CL04
C17H14ClO4
JANUVIA
Various Metabolites and Impurities
Intermediates & Fine Chemicals
Metabolites & Impurities
Pharmaceuticals
pharmacetical
Aromatics