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Fenofibrate

CAS No.: 49562-28-9

Chemical Name:: Fenofibrate

Synonyms: sedufen;Fenoglide;lf-178;lipsin;Lipirex;Liposit;Nolipax;Secalip;LIPYDIL;lipidax

CBNumber:: CB8266802

Molecular Formula:: C20H21ClO4

Molecular Weight:: 360.83

MOL File:: 49562-28-9.mol

MSDS File:: SDS

Modify Date:: 2024/7/26 15:15:06

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Fenofibrate Properties

Melting point	80-810C
Boiling point	469.8±35.0 °C(Predicted)
Density	1.177±0.06 g/cm3(Predicted)
storage temp.	room temp
solubility	Practically insoluble in water, very soluble in methylene chloride, slightly soluble in ethanol (96 per cent)
form	powder
color	off-white
Water Solubility	0.8mg/L(25 ºC)
Merck	14,3978
BCS Class	2
InChI	InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
InChIKey	YMTINGFKWWXKFG-UHFFFAOYSA-N
SMILES	C(OC(C)C)(=O)C(OC1=CC=C(C(=O)C2=CC=C(Cl)C=C2)C=C1)(C)C
EPA Substance Registry System	Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester (49562-28-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Warning

Hazard statements

H412

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

RTECS

UA2453400

HS Code

29189900

Toxicity

LD50 in mice: 1600 mg/kg orally (Sornay)

NFPA 704

	0
3		0

Fenofibrate price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	F6020	Fenofibrate ≥99%, powder	49562-28-9	5G	₹5975.4	2022-06-14	Buy
Sigma-Aldrich(India)	PHR1246	Fenofibrate Pharmaceutical Secondary Standard; Certified Reference Material	49562-28-9	500MG	₹10695.1	2022-06-14	Buy
Sigma-Aldrich(India)	F6020	Fenofibrate ≥99%, powder	49562-28-9	25G	₹18142.7	2022-06-14	Buy
Sigma-Aldrich(India)	F6020	Fenofibrate ≥99%, powder	49562-28-9	100G	₹54601.3	2022-06-14	Buy
Sigma-Aldrich(India)	55443	Fenofibrate analytical standard	49562-28-9	100MG	₹6354.28	2022-06-14	Buy

Product number	Packaging	Price	Buy
F6020	5G	₹5975.4	Buy
PHR1246	500MG	₹10695.1	Buy
F6020	25G	₹18142.7	Buy
F6020	100G	₹54601.3	Buy
55443	100MG	₹6354.28	Buy

Fenofibrate Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

Fenofibrate has been used:

to study its effect on plasma lipids, liver phenotype and gene expression
to study its impact on endothelium-dependent vasodilatation of thoracic aorta
to administer to NASH knock-in mice along with a high fat diet (HFD) to study its effect

Definition

ChEBI: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.

General Description

Fenofibrate, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methylethyl ester (Tricor),has structural features represented in clofibrate. The primarydifference involves the second aromatic ring. This imparts agreater lipophilic character than exists in clofibrate, resultingin a much more potent hypocholesterolemic and triglycerideloweringagent. Also, this structural modification results in alower dose requirement than with clofibrate or gemfibrozil.

Fenofibrate Preparation Products And Raw materials

Raw materials

Anisole 4-Chlorobenzoyl chloride Thionyl chloride Isopropyl alcohol 4-Chloro-4'-hydroxybenzophenone

Sodium hydroxide Chloroform Acetone ISOPROPYL 2-(4-BROMOPHENOXY)-2-METHYLPROPANOATE Fenofibric acid

Dihydro Fenofibrate 9-Methylfluorene-9-carbonyl chloride Isopropyl 2-bromo-2-methylpropanoate 1-Chloro-4-iodobenzene 4-Chlorophenylboronic acid

2-Bromopropane 4-Bromochlorobenzene 4-Chlorobenzaldehyde

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Preparation Products

Fenofibrate Suppliers

Global( 707)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Jigs Chemical ltd	+919099003427	Gujarat, India	239	58	Inquiry
Vihita Chem Private Limited	+91-9512002673 +91-9512002673	Gujarat, India	122	58	Inquiry
SURYA LIFE SCIENCES LIMITED	+91-2646226290 +91-9428511112	Gujarat, India	62	58	Inquiry
ANWITA APIS	+919000311012	Hyderabad, India	198	58	Inquiry
Micro Orgo Chem	+91-91-022-24969510 +91-9082984052	Mumbai, India	66	58	Inquiry
J S LABS	+91-7330612784 +91-7330612784	Tamil Nadu, India	160	58	Inquiry
AARTIA KEM SCIENCE	+91-8291072530 +91-8291072530	Maharashtra, India	70	58	Inquiry
Nivika Chemo Pharma Pvt Ltd	+91-9824176501 +91-9824176501	Gujarat, India	15	58	Inquiry
Lupin Ltd	+91-8019896181 +91-8019896181	Maharashtra, India	93	58	Inquiry
Aalidhra Pharmachem Pvt Ltd	+91-9879180894 +91-9879180894	Gujarat, India	38	58	Inquiry

Supplier	Advantage
Jigs Chemical ltd	58
Vihita Chem Private Limited	58
SURYA LIFE SCIENCES LIMITED	58
ANWITA APIS	58
Micro Orgo Chem	58
J S LABS	58
AARTIA KEM SCIENCE	58
Nivika Chemo Pharma Pvt Ltd	58
Lupin Ltd	58
Aalidhra Pharmachem Pvt Ltd	58

Fenofibrate Spectrum

Fenofibrate(49562-28-9)¹HNMR

49562-28-9(Fenofibrate)Related Search:

4-Chloro-4'-hydroxybenzophenone Isopropyl acetate Tris(trimethylsilyl)phosphate Isopropyl alcohol Propyl gallate

Propyl acetate FENOFIBRATE ACID Isopropyl palmitate ISOPROPYL LAURATE Isopropyl myristate

Methyl acrylate FENOFIBRATE RELATED COMPOUND C (25 MG) (1-METHYLETHYL 2-[[2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOYL]OXY]-2-METHYLPROPANOATE) (4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone (Fenofibrate IMpurity) 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid methyl ester Unii-4bmh7izt98

3-[4-(4-Chlorobenzoyl)phenoxy]-2-butanone (Fenofibrate IMpurity) FENOFIBRIC ACID ETHYL ESTER FENOFIBRATE IMPURITY B,Fenofibrate Related Compound B

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2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-propanoicaci1-methylethylester isopropyl(4’-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate isopropyl2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate lf-178 lipantil procetofen proctofene Fenofibrate, >=99% 2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoic acid ethyl ester ethyl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, ethyl ester 2-[4-(4-CHLOROBENZOYL)PHENOXYL-2-METHYLPROPANOIC ACID 1-METHYLETHYL ESTER 2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYL-PROPANOIC ACID, 1-METHYLETHYL ESTER 2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOIC ACID ISOPROPYL ESTER 2-[4-[p-Chlorobenzoyl]]-2-methylpropionic acid isopropyl ester Isopropyl 2-[p-[p-chlorobenzoyl] phenoxy]-2-methylpropionate Lipantyl Procetofene Lipidil Supra Lipirex Liposit MeltDose Nolipax NSC 281319 Fenofibrite propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate Elasterin Secalip 2-[p-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid isopropyl ester LIPYDIL LIPANTHYL LABOTEST-BB LT00771982 FENOFIBRATE 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propionic acid isopropyl ester propan-2-yl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate Fenofibrate,2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester Fenofibrate (200 mg) Fenofibrate API Fenofibrate COS 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester Isopropyl 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionate lipidax lipifen lipoclar lipofene lipsin Felodipine Solution, 100ppm Fenofibrate Solution, 1000ppm Fenobrate 2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoic acid propan-2-yl ester Fenofibrate CRS Fenofibrate> Fenofibrate, 98%, reagent grade Lipanty Fenofibrate,>98% Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester Fenofibrate USP/EP/BP fat fenofibrat Lipofen