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Diethyl acetylenedicarboxylate

Diethyl acetylenedicarboxylate Structure
CAS No.
762-21-0
Chemical Name:
Diethyl acetylenedicarboxylate
Synonyms
Diethyl but-2-ynedioate;DIETHYL BUTYNEDIOATE;Diethyl 2-butynedioate;YL2-BUTYNEDIOATE;Diethyl butyrate;Diethyl acetylenedic;diethylbut-2-indioat;Bis(carboethoxy)acetylene;Diethyl but-2-yne-1,4-dioate;Bis-(Ethoxycarbonyl)acetylene
CBNumber:
CB8456726
Molecular Formula:
C8H10O4
Molecular Weight:
170.16
MOL File:
762-21-0.mol
MSDS File:
SDS
Modify Date:
2024/6/18 13:26:42

Diethyl acetylenedicarboxylate Properties

Melting point 1-3 °C
Boiling point 107-110 °C11 mm Hg(lit.)
Density 1.063 g/mL at 25 °C(lit.)
refractive index n20/D 1.443(lit.)
Flash point 202 °F
storage temp. 2-8°C
form Liquid
Specific Gravity 1.063
color Clear light yellow
Water Solubility Soluble in ethanol, ethyl ether, CCl4, Insoluble in water.
BRN 743166
CAS DataBase Reference 762-21-0(CAS DataBase Reference)
NIST Chemistry Reference Diethylacetylene dicarboxylate(762-21-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45-25
RIDADR  UN 3265 8/PG 2
WGK Germany  3
8-10
HazardClass  8
PackingGroup  III
HS Code  29171990
NFPA 704
0
3 0

Diethyl acetylenedicarboxylate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 159441 Diethyl acetylenedicarboxylate 95% 762-21-0 5G ₹3225.85 2022-06-14 Buy
Sigma-Aldrich(India) 159441 Diethyl acetylenedicarboxylate 95% 762-21-0 5G ₹3225.85 2022-06-14 Buy
Sigma-Aldrich 159441 Diethyl acetylenedicarboxylate 95% 762-21-0 25G ₹10283.75 2022-06-14 Buy
Sigma-Aldrich(India) 159441 Diethyl acetylenedicarboxylate 95% 762-21-0 25G ₹10283.75 2022-06-14 Buy
Sigma-Aldrich 159441 Diethyl acetylenedicarboxylate 95% 762-21-0 100G ₹16410.7 2022-06-14 Buy
Product number Packaging Price Buy
159441 5G ₹3225.85 Buy
159441 5G ₹3225.85 Buy
159441 25G ₹10283.75 Buy
159441 25G ₹10283.75 Buy
159441 100G ₹16410.7 Buy

Diethyl acetylenedicarboxylate Chemical Properties,Uses,Production

Chemical Properties

Diethyl acetylenedicarboxylate is a clear light yellow liquid which has a disagreeable smell. It is a cheap and readily available material in industry. The triple bond is a critical and useful functional group, and it has extensive applications in organic synthesis. It can react with amines, aldehydes, ketones, etc. Therefore it can be used to form various heterocycles.
Synthesis of diethyl acetylenedicarboxylate
Synthesis of diethyl acetylenedicarboxylate

Uses

Diethyl acetylenedicarboxylate is used as a protein cross-linker. It is also used in the synthesis of 3,4,5-trisubstituted 2(5H)-furanone derivatives, highly functionalized thiazolidinone derivatives, novel cyclic peroxide glucosides and 4,11-dimesitylbisanthene, soluble bisanthene derivative, via Diels-Alder reaction.

General Description

Diethyl acetylenedicarboxylate is a protein cross-linker.

Purification Methods

Dissolve the ester in *C6H6, wash it with NaHCO3, H2O, dry over Na2SO4, filter, evaporate and distil it in a vacuum [IR: Walton & Hughes J Am Chem Soc 79 3985 1957, Truce & Kruse J Am Chem Soc 81 5372 1959]. [Beilstein 2 H 803.]

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Diethyl acetylenedicarboxylic acid Diethyl acetylenedicarboxylate,97% Diethyl acetylenedic Diethyl acetylenedicarboxylate, 97% 25GR Diethyl acetylenedicarboxylate 95% Diethyl acetylenedicarboxylate, 98%+ Bis-(Ethoxycarbonyl)acetylene butynedioic acid diethyl ester YL2-BUTYNEDIOATE Diethyl but-2-yne-1,4-dioate DIETHYL ACETYLENEDICARBOXYLATE 2-butynedioic acid diethyl ester ACETYLENEDICARBOXYLIC ACID DIETHYL ESTER but-2-ynedioic acid diethyl ester Bis(carboethoxy)acetylene Diethyl Acetylenedicarboxylate > DIETHYL ACETYLENEDICARBOXYLATE FOR SYNTH Diethyl butyrate 2-Butynedioic acid, 1,4-diethyl ester Diethyl acetylenedicarboxylate ISO 9001:2015 REACH Diethyl but-2-ynedioate Diethyl 2-butynedioate DIETHYL BUTYNEDIOATE diethylbut-2-indioat 762-21-0 CH3CH2O2CCCCO2CH2CH3 C2H5OCOC8801CCOOC2H5 Acetylenes Acetylenic Carboxylic Acids & Their Derivatives Organic Building Blocks Esters Building Blocks Carbonyl Compounds C8 to C9 Aromatic Esters Miscellaneous Acetylenes Acetylenic Carboxylic Acids & Their Derivatives bc0001