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Maltitol

Maltitol Structure
CAS No.
585-88-6
Chemical Name:
Maltitol
Synonyms
D-MALTITOL;malbit;MALTITOL-BASEDPRODUCTS;titoL;maltit;maltimr;MALTITOL;maltisorb;amaltymr100;amaltisyrup
CBNumber:
CB8726683
Molecular Formula:
C12H24O11
Molecular Weight:
344.31
MOL File:
585-88-6.mol
MSDS File:
SDS
Modify Date:
2024/8/7 19:09:42

Maltitol Properties

Melting point 149-152 °C (lit.)
alpha [α]D20 +106~+108゜ (c=0.8, H2O)
Boiling point 399.42°C (rough estimate)
Density 1.3863 (rough estimate)
vapor pressure 0.001Pa at 20℃
refractive index 105 ° (C=10, H2O)
storage temp. 2-8°C
solubility Very soluble in water, practically insoluble in anhydrous ethanol.
form Crystalline Powder
pka 12.84±0.70(Predicted)
color White
Water Solubility Soluble in water. Slightly soluble in ethanol.
BRN 89983
Stability Hygroscopic
LogP -3.87 at 24℃
CAS DataBase Reference 585-88-6(CAS DataBase Reference)
EPA Substance Registry System D-Glucitol, 4-O-.alpha.-D-glucopyranosyl- (585-88-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
WGK Germany  3
RTECS  LZ4394000
TSCA  Yes
HS Code  29400090
NFPA 704
1
1 0

Maltitol price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1248 Maltitol Pharmaceutical Secondary Standard; Certified Reference Material 585-88-6 500MG ₹7371.83 2022-06-14 Buy
Sigma-Aldrich(India) M8892 Maltitol ≥98% 585-88-6 25G ₹9200 2022-06-14 Buy
Sigma-Aldrich(India) M8892 Maltitol ≥98% 585-88-6 100G ₹18792.2 2022-06-14 Buy
TCI Chemicals (India) M0797 Maltitol min. 98.0 % 585-88-6 25G ₹2600 2022-05-26 Buy
TCI Chemicals (India) M0797 Maltitol min. 98.0 % 585-88-6 100G ₹3700 2022-05-26 Buy
Product number Packaging Price Buy
PHR1248 500MG ₹7371.83 Buy
M8892 25G ₹9200 Buy
M8892 100G ₹18792.2 Buy
M0797 25G ₹2600 Buy
M0797 100G ₹3700 Buy

Maltitol Chemical Properties,Uses,Production

Description

Maltitol is a-D-glucopyranosyl-1.4-glucitol. The solubility in water is approximately 1,750 g/L at room temperature. Maltitol is stable under the common processing conditions of foods. In addition to dry maltitol several types of syrups are available.
Maltitol is, depending on the concentration, approximately 90 % as sweet as sucrose and noncariogenic.
In the European Union, maltitol is approved as E 965 for a large number of food applications. It is GRAS in the United States and also approved in many other countries.

Chemical Properties

Maltitol is a-D-glucopyranosyl-1.4-glucitol. The solubility in water is approximately 1,750 g/L at room temperature. Maltitol is stable under the common processing conditions of foods. In addition to dry maltitol several types of syrups are available.
Maltitol is, depending on the concentration, approximately 90 % as sweet as sucrose and noncariogenic .
In the European Union, maltitol is approved as E 965 for a large number of food applications. It is GRAS in the United States and also approved in many other countries.

Uses

Maltitol is a polyhydric alcohol (polyol) produced by hydrogenation of maltose. it is approximately 90% as sweet as sucrose, has good stability, and is nonhygroscopic. uses include chewing gum, dry nut bakery products, and chocolate.

Production Methods

Maltitol is produced by chemical hydrogenation of maltose, which can be obtained by enzymatic degradation of starch under conditions similar to those used for other starch hydrolysates such as glucose. The Starting material can be the different commercially available starches including corn, potato, and others. A partially degraded starch, which can be obtained by treatment with diluted hydrochloric or sulphuric acid and subsequent neutralization or with heat-stable a-amylase, is then subjected to enzyme treatment for further degradation to maltose-rich products.
Enzymes used for maltose production are b-amylases, fungal a-amylases, a-1.6- glucosidases, maltogenic amylases, and debranching enzymes, preferably with high temperature optimum.

Definition

ChEBI: An alpha-D-glucoside consisting of D-glucitol having an alpha-D-glucosyl residue attached at the 4-position. Used as a sugar substitute.

General Description

Maltitol is a low-caloric artificial sweetener, consisting of a sugar alcohol (polyol),

Pharmaceutical Applications

Maltitol is widely used in the pharmaceutical industry in the formulation of oral dosage forms. It is a noncariogenic bulk sweetener, approximately as sweet as sucrose, well adapted as a diluent for different oral dosage forms, wet granulation, and sugarfree hard coating.

Safety

Maltitol is used in oral pharmaceutical formulations, confectionery, and food products, and is considered to be noncariogenic. It is generally regarded as a nontoxic, nonallergenic, and nonirritant material.
Digestion of maltitol follows two different metabolic pathways: absorption in the small intestine and fermentation in the large intestine (colon). These two metabolic pathways must thus be considered when evaluating the energy value. The hydrolysis of maltitol in the small intestine releases sorbitol and glucose. Glucose is actively transported and rapidly absorbed, whereas sorbitol absorption is passive. The nonabsorbed sorbitol and nonhydrolyzed maltitol are fermented by the microflora in the colon. The relative importance of the two absorption pathways depends on numerous individual factors and is related to the quantity of maltitol ingested. Excessive oral consumption (>50 g daily) may cause flatulence and diarrhea.
Maltitol exhibits a low glycemic index and can therefore, under medical supervision, have a place in the diet of diabetic patients. The intake of maltitol must be taken into account for the calculation of the daily glucidic allowance.
The WHO, in considering the safety of maltitol, did not set a value for the acceptable daily intake since the levels used in food to achieve a desired effect were not considered a hazard to health.

storage

Maltitol has good thermal and chemical stability. When it is heated at temperatures above 200°C, decomposition begins (depending on time, temperature, and other prevailing conditions). Maltitol does not undergo browning reactions with amino acids, and absorbs atmospheric moisture only at relative humidities of 89% and above, at 20°C.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in oral pharmaceutical formulations. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Maltitol Preparation Products And Raw materials

Raw materials

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Preparation Products

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4-O-.alpha.-D-GlucopyronosylD-sorbitol GLUCITOL,4-O-ALPHA-D-GLUCOPYRANOSYL,D- MALTITOLSYRUP 4-o-alpha-d-glucopyranosyl-d-glucito amaltisyrup amaltymr100 d-4-o-alpha-d-glucopyranosylglucitol Alpha-D-Glucopyranosy1-1, 4-D-Glucitol 6-O-A-D-GALACTOPYRANOSYL-D-GLUCOPYRANOSE Maltitol syruo Maltitol,95% 4-.alpha.-D-Glucopyranosyl-D-sorbitol 4-O-alpha-Glucopyranosyl-D-glucitol D-Maltitol ,98% Maltitol,4-O-α-Glucopyranosyl-D-sorbitol Maltitol (200 mg) Maltitol, 95% 25GR Maltsugar alcohol maltimr maltisorb maltit MALTITOL 4-O-ALPHA-D-GLUCOPYRANOSYL-D-GLUCITOL 4-O-ALPHA-GLUCOPYRANOSYL-D-SORBITOL D-Glucitol, 4-O-.alpha.-D-glucopyranosyl- 4-o-à-d-glucopyranosyl-d-glucitol 4-o-α-glucopyranosyl-d-sorbitol 4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol GLUCOPYRANOSYLSORBITOL HYDROGENATEDGLUCOSESYRUP MALTITOL CRYSTALLINE DRY FORM MALTIT 98%, KRIST. MALTITOL, CRYSTALLIZED MALTITOL, USP STANDARD MALTITOL, EP STANDARD Maltitol,97% Maltitol Syrup 585-88-6 kf-wang(at)kf-chem.com D-Glucitol, 4-O-a-D-glucopyranosyl- titoL Maltitol Solution 50% Maltitol> Maltitol CRS 3-O-beta-D-galactopyranosyl-D-allitol Erythritol Impurity 1 (Erythritol EP Impurity A) (2S,3R,4R,5R)-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,5,6-pentaol LIQUID MALTITOL FOOD Maltitol Crystal Maltitol USP/EP/BP Wholesale Price Maltitol Powder / Syrup 75% 80% CAS No 585-88-6 Mannitol EP Impurity B Maltitol (1374907) MALTITOL-BASEDPRODUCTS malbit D-MALTITOL 4-O-α-glucopyranosyl-D-sorbitol Maltitol powder Maltitol 4-O-α-D-glucopyranosyl-D-glucitol (D-maltitol) D-Glucitol, 4-O-α-D-glucopyranosyl-