Emedastine

CAS No.: 87233-61-2

Chemical Name:: Emedastine

Synonyms: EMEDASTINE;Emedastine impurity F;Emedastine Impurity 14;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole;1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole;1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole;1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole;1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole;1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole;allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis

CBNumber:: CB8728076

Molecular Formula:: C17H26N4O

Molecular Weight:: 302.41

MOL File:: 87233-61-2.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:37

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Emedastine Properties

Boiling point	446.6±55.0 °C(Predicted)
Density	1.15±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 125 mg/mL (413.35 mM); Ethanol: 100 mg/mL (330.68 mM)
pka	8.86±0.10(Predicted)
form	Viscous Liquid
color	Yellow to brown
CAS DataBase Reference	87233-61-2(CAS DataBase Reference)

Emedastine Chemical Properties,Uses,Production

Uses

Antihistaminic, H1-receptor; asthma prophylactic; anti-allergic.

Definition

ChEBI: 1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the ifumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.

Clinical Use

Emedastine also is a newer antihistamine used topically in the eye for conjunctivitis. It has very high H1 receptor selectivity characteristics, and it is structurally related to the benzimidazoles, such as astemizole. Inhibition of mast cell release of inflammatory mediators has been noted.

Emedastine Preparation Products And Raw materials

Raw materials

N-(2-ETHOXY-ETHYL)-BENZENE-1,2-DIAMINE (2-ETHOXY-ETHYL)-(2-NITRO-PHENYL)-AMINE EMEDASTINE IMPURITY E 1-(2-ETHOXY-ETHYL)-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE 1H-BENZIMIDAZOLE,2-CHLORO-1-(2-ETHOXYETHYL)

1-Boc-hexahydro-1,4-diazepine N-Methylhomopiperazine 2-Chlorobenzimidazole Aniline Formaldehyde

2-Nitrochlorobenzene

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Preparation Products

Emedastine Suppliers

Global( 83)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ArkGen Pharma Private Limited	09844366764	Karnataka, India	20	58	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9338	55	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	China	25363	58	Inquiry
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	China	3136	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry

Supplier	Advantage
ArkGen Pharma Private Limited	58
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58

Emedastine Spectrum

Emedastine(87233-61-2)¹HNMR

87233-61-2(Emedastine)Related Search:

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Methyl salicylate Tribenuron methyl Basic Violet 1 Methyl acrylate Benzimidazole

Methylparaben Cilastatin Phenformin Imipenem-Cilastatin sodium hydrate Kresoxim-methyl

Methanol Sodium 1-heptanesulfonate Methyl

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EMEDASTINE 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole 1-(2-Ethoxyethyl)-2-(4-methylhexahydro-1H-1,4-diazepine-1-yl)-1H-benzimidazole 1-(2-Ethoxyethyl)-2-[(hexahydro-4-methyl-1H-1,4-diazepin)-1-yl]-1H-benzimidazole 1-(2-ethoxyethyl)-2-(4-Methyl-1,4-diazepan-1-yl)-1H-1,3-benzodiazole 1-(2-Ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzo[d]imidazole Emedastine impurity F allergic,Histamine Receptor,antiallergic,benzimidazole,Inhibitor,skin,inhibit,Emedastine,orally,rhinitis,diseases,conjunctivitis Emedastine Impurity 14 87233-61-2 C17H26N4O impurity DCP