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PAGOCLONE

PAGOCLONE Structure
CAS No.
133737-32-3
Chemical Name:
PAGOCLONE
Synonyms
Ip 456;CI-1043;RP 59037;AGOCLONE;Rp 62955;(+)-Pagoclone;(+)-RP-59037; IP-456; RP-62955; CI-1043;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one
CBNumber:
CB8839954
Molecular Formula:
C23H22ClN3O2
Molecular Weight:
407.89
MOL File:
133737-32-3.mol
Modify Date:
2024/7/2 8:55:39
Request For Quotation

PAGOCLONE Properties

Boiling point 582.1±50.0 °C(Predicted)
Density 1.273±0.06 g/cm3(Predicted)
pka 1.62±0.30(Predicted)
form Solid
color White to off-white
InChI InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKey HIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILES C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2

PAGOCLONE Chemical Properties,Uses,Production

Description

Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.

Uses

Anti-anxiety agent.

Application

Pagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition.

brand name

Bextra (Interneuron).

PAGOCLONE Preparation Products And Raw materials

Raw materials

Preparation Products

PAGOCLONE Suppliers

Global( 52)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Xi'an MC Biotech, Co., Ltd. 029-89275612 +8618991951683 China 2255 58 Inquiry
airuikechemical co., ltd. +undefined86-15315557071 China 983 58 Inquiry
Dorne Chemical Technology co. LTD +86-86-13583358881 +8618560316533 China 3126 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Shanghai UCHEM Inc. +862156762820 +86-13564624040 China 7181 58 Inquiry
Finetech Industry Limited +86-27-87465837 +8618971612321 China 9640 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
ShanDong Look Chemical Co.,Ltd. +8617653113219 China 2739 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Xi'an MC Biotech, Co., Ltd. 58
airuikechemical co., ltd. 58
Dorne Chemical Technology co. LTD 58
BOC Sciences 58
Shanghai UCHEM Inc. 58
Finetech Industry Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
ShanDong Look Chemical Co.,Ltd. 58
TargetMol Chemicals Inc. 58

PAGOCLONE Spectrum

PAGOCLONE(133737-32-3)1HNMR

133737-32-3(PAGOCLONE)Related Search:

Risperidone Venlafaxine IMIPRAMINE Olanzapine PAGOCLONE
2-CHLORO-1,8-NAPHTHYRIDINE
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2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone RP 59037 Ip 456 Rp 62955 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one (+)-RP-59037; IP-456; RP-62955; CI-1043 CI-1043 AGOCLONE inhibit,GABA Receptor,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,IP 456,RP 62955,RP62955,Pagoclone,Inhibitor (+)-Pagoclone 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one 133737-32-3 C23H22ClN3O2