Fluprednisolone
- CAS No.
- 53-34-9
- Chemical Name:
- Fluprednisolone
- Synonyms
- Alphadrol;U-7800;Etadrol;NSC-47439;fluprednisolone;6α-Fluprednisolone;6-a-Fluorprednisolone;6a-fluoroprednisolone;6-α-fluoroprednisolone;6alpha-Fluprednisolone
- CBNumber:
- CB8854834
- Molecular Formula:
- C21H27FO5
- Molecular Weight:
- 378.43
- MOL File:
- 53-34-9.mol
- Modify Date:
- 2024/12/18 14:08:57
| Melting point | 208-213° |
|---|---|
| alpha | D +92° |
| Density | 1.1023 (rough estimate) |
| refractive index | 1.5980 (estimate) |
| storage temp. | Refrigerator |
| solubility | Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White |
| Water Solubility | 174.2mg/L(20 ºC) |
| EPA Substance Registry System | Fluprednisolone (53-34-9) |
SAFETY
Risk and Safety Statements
| WGK Germany | 3 |
|---|---|
| Hazardous Substances Data | 53-34-9(Hazardous Substances Data) |
Fluprednisolone Chemical Properties,Uses,Production
Description
Fluprednisolone (6α-fluoro-11β,17,21-trihydroxy-pregna-1,4-diene-3,20-dione) is the 16-desmethyl analogue of paramethasone. Its activity is similar to that of paramethasone, and it has approximately 2.5 times the antirheumatic potency of prednisolone. With doses of 2 to 7 mg, evidence of salt and water retention has not been noted. The therapeutic index, however, probably is the same or only a little greater than that for prednisolone. Because no new adverse reactions have been noted during the administration of this drug on a short-term basis, it seems that a 6α-fluoro group does not deleteriously affect the activity of prednisolone (49,75).
Uses
6α-Fluprednisolone is an anti-inflammatory corticosteroid metabolite.
Fluprednisolone Preparation Products And Raw materials
Fluprednisolone Suppliers
Global( 56)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 3978 | 58 | Inquiry |
| Nanjing Shizhou Biotechnology Co., Ltd | +86-15850508050 +86-15850508050 | China | 323 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32159 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34563 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | China | 52849 | 58 | Inquiry |
| TargetMol Chemicals Inc. | United States | 38630 | 58 | Inquiry | |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49984 | 58 | Inquiry |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | China | 11922 | 58 | Inquiry |
53-34-9(Fluprednisolone)Related Search:
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6-a-Fluorprednisolone
6-α-fluoroprednisolone
6ALPHA-FLUPREDINSOLONE,97%MIN
6a-Fluoro-11b,17,21-trihydroxypregna-1,4-diene-3,20-dione
6a-Fluoro-11b,17a,21-trihydroxypregna-1,4-diene-3,20-dione
6α-Fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
Etadrol
NSC-47439
U-7800
(6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6S,8S,9S,10R,11S,13S,14S,17R)-6-fluoro-17-glycoloyl-11,17-dihydroxy-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
fluprednisolone
6a-fluoroprednisolone
Fluprednisolone Solution, 100ppm
Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-, (6α,11β)-
6alpha-Fluprednisolone
Alphadrol
Fluprednisolone,methylprednisolone,prednisolone,prednisone,Addison's disease,6α-Fluoroprednisolone,Inhibitor,congenital adrenal virilism,inhibit
6α-Fluprednisolone
Methylprednisolone Impurity 28
Fluprednisolone, 10 mM in DMSO
53-34-9
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