Estradiol benzoate
![Estradiol benzoate Structure](CAS/GIF/50-50-0.gif)
- CAS No.
- 50-50-0
- Chemical Name:
- Estradiol benzoate
- Synonyms
- ODB;MEE;Oestradiol benzoate;EBZ;folone;17β-Estradiol benzoate;(17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate;ESTON-B;diogynb;Graafina
- CBNumber:
- CB9131644
- Molecular Formula:
- C25H28O3
- Molecular Weight:
- 376.5
- MOL File:
- 50-50-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/4 16:55:17
Melting point | 191-198 °C(lit.) |
---|---|
alpha | D25 +58 to +63° (c = 2 in dioxane) |
Boiling point | 465.03°C (rough estimate) |
Density | 1.0493 (rough estimate) |
refractive index | 1.5460 (estimate) |
storage temp. | 2-8°C |
solubility | Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in acetone, slightly soluble in methanol. |
form | Solid |
pka | 15.06±0.40(Predicted) |
color | White |
Water Solubility | 0.4mg/L(25 ºC) |
Merck | 3703 |
BRN | 3107526 |
CAS DataBase Reference | 50-50-0(CAS DataBase Reference) |
NIST Chemistry Reference | Estradiol benzoate(50-50-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H351-H360FD |
Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
Hazard Codes | T |
Risk Statements | 60-61-40 |
Safety Statements | 53-22-36/37/39-45 |
WGK Germany | 3 |
RTECS | KG4050000 |
F | 8 |
HS Code | 29372319 |
Estradiol benzoate price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | E8515 | β-Estradiol 3-benzoate ≥97% | 50-50-0 | 200MG | ₹2662.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E8515 | β-Estradiol 3-benzoate ≥97% | 50-50-0 | 1G | ₹6971.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR2858 | Estradiol Benzoate certified reference material, pharmaceutical secondary standard | 50-50-0 | 500MG | ₹26369.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | E8515 | β-Estradiol 3-benzoate ≥97% | 50-50-0 | 5G | ₹23923.25 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 46552 | β-Estradiol 3-benzoate VETRANAL?, analytical standard | 50-50-0 | 10MG | ₹6473.35 | 2022-06-14 | Buy |
Estradiol benzoate Chemical Properties,Uses,Production
Chemical Properties
White solid
Definition
ChEBI: A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.
Clinical Use
Estradiol is a semisynthetic estrogen compound. Its effects will mimic that of estrogen in animals. The most common use in small animals has been to terminate pregnancy.
Estradiol benzoate also has been used to terminate pregnancy (5-10 mg/kg divided into two or three SQ injections). Estradiol cypionate formulation had high efficacy (95%), but it had serious adverse effects and is not recommended. Estradiol cypionate is longer acting and more potent than other estrogen formulations. Estradiol valerate injection (20 mg/mL) is also available for human medicine to treat hypoestrogenism.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Human reproductive effects by intramuscular route: menstrual cycle changes and disorders. Experimental reproductive effects. Mutation data reported. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.
Estradiol benzoate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Asg Biochem Pvt. Ltd | +91-9650436669 +91-9650436669 | New Delhi, India | 25 | 58 | Inquiry |
A.B.ENTERPRISES | +91-9223381464 +91-9223381464 | Maharashtra, India | 78 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Shakti Life Science | +91-9930420063 +91-9930420063 | Maharashtra, India | 28 | 58 | Inquiry |
Vincit Labs Pvt Ltd | +91-1127357490 +91-1127357490 | New Delhi, India | 15 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Sanjivani Pharma | 08048371780Ext 182 | Gujarat, India | 8 | 58 | Inquiry |
ASG Biochem | 09958992614 | Delhi, India | 1 | 58 | Inquiry |
Queens Pharmaceuticals | 07267768980 | Mumbai, India | 1 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Asg Biochem Pvt. Ltd | 58 |
A.B.ENTERPRISES | 58 |
Ralington Pharma | 58 |
Shakti Life Science | 58 |
Vincit Labs Pvt Ltd | 58 |
Triveni chemicals | 58 |
Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
Sanjivani Pharma | 58 |
ASG Biochem | 58 |
Queens Pharmaceuticals | 58 |
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