ChemicalBook > Product Catalog >API >Antiallergic drugs >Antihistamines >Levocetirizine dihydrochloride
Levocetirizine dihydrochloride
- CAS No.
- 130018-87-0
- Chemical Name:
- Levocetirizine dihydrochloride
- Synonyms
- DDDB;LevocetrizineHCl;LEVOCETIRIZINE HCL;Levocetirizine HCI;Levocitirizine 2HCL;LEVOCETIRIZINE 2HCL;LEVOCETIRIZINE DIHCL;(R)-Cetirizine DiHCl;Xyzal Dihydrochloride;(R)-Form dihydrochloride
- CBNumber:
- CB9135031
- Molecular Formula:
- C21H27Cl3N2O3
- Molecular Weight:
- 461.81
- MOL File:
- 130018-87-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/10 17:26:08
| Melting point | 215-220°C |
|---|---|
| alpha | D25 -12.79° (c = 1 in water) |
| storage temp. | room temp |
| solubility | H2O: ≥23mg/mL |
| form | powder |
| color | White to Almost white |
| Merck | 14,2022 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 130018-87-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H400 | |||||||||
| Precautionary statements | P273-P301+P312+P330 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 22-50/53 | |||||||||
| Safety Statements | 60-61 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AG0990000 | |||||||||
| HS Code | 29335990 | |||||||||
| NFPA 704 |
|
Levocetirizine dihydrochloride price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | L7795 | Levocetirizine dihydrochloride ≥98% (HPLC) | 130018-87-0 | 10MG | ₹9536.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | L7795 | Levocetirizine dihydrochloride ≥98% (HPLC) | 130018-87-0 | 50MG | ₹38017.4 | 2022-06-14 | Buy |
| TCI Chemicals (India) | L0264 | Levocetirizine Dihydrochloride | 130018-87-0 | 1G | ₹5100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | L0264 | Levocetirizine Dihydrochloride | 130018-87-0 | 5G | ₹15200 | 2022-05-26 | Buy |
Levocetirizine dihydrochloride Chemical Properties,Uses,Production
Uses
Levocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.
General Description
Levocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. ThisR-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H1-receptors.Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .
Biochem/physiol Actions
Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.
Levocetirizine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 513)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TAGOOR LABORATORIES PVT LTD | +919700187008 | AndhraPradesh, India | 93 | 58 | Inquiry |
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| ANWITA APIS | +919000311012 | Hyderabad, India | 198 | 58 | Inquiry |
| Dr. Reddy's Laboratories Ltd | +91-4049002900 +91-4049002900 | Hyderabad, India | 165 | 58 | Inquiry |
| HEMA PHARMACEUTICALS PVT LTD | +91-9537936912 +91-9537936912 | Gujarat, India | 48 | 58 | Inquiry |
| Frolic Pharmachem | +919711094561 | Himachal Pradesh, India | 94 | 58 | Inquiry |
| ALMELO PRIVATE LIMITED | +91-9100991345 +91-8500807769 | Telangana, India | 114 | 58 | Inquiry |
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Metrochem API Private Limited | +91-4069069999 +91-4069069999 | Telangana, India | 78 | 58 | Inquiry |
| Styrax Pharma Pvt Ltd | +91-4048583333 +91-9848912103 | Telangana, India | 24 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| TAGOOR LABORATORIES PVT LTD | 58 |
| Jigs Chemical ltd | 58 |
| ANWITA APIS | 58 |
| Dr. Reddy's Laboratories Ltd | 58 |
| HEMA PHARMACEUTICALS PVT LTD | 58 |
| Frolic Pharmachem | 58 |
| ALMELO PRIVATE LIMITED | 58 |
| Gonane Pharma | 58 |
| Metrochem API Private Limited | 58 |
| Styrax Pharma Pvt Ltd | 58 |
130018-87-0(Levocetirizine dihydrochloride)Related Search:
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LEVOCETIRIZINE 2HCL
LEVOCETIRIZINE DIHCL
LEVOCETIRIZINE DIHYDROCHLORIDE
LEVOCETIRIZINE HCL
LEVOCETRIZINE DIHYDROCHLORIDE
[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride
LevocetrizineHCl
LEVOCITIRIZINE DIHYDROCHLORIDE
(R) -2-[2-[4-[(4-Chlorophenyl) phenylmethyl] piperazin-1-yl]ethoxy]acetic acid dihydrochloride
(2-(4-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl)ethoxy)acetic acid dihydrochloride
Levocitirizine 2HCL
(R)-Cetirizine diHCl (Levocetirizine diHCl)
Levocetirizine dihydrochloride [2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride
2-[2-[4-[(R)-(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride
DDDB
Cetirizine hydrochloride sinistral
(R)-Form dihydrochloride
[2-[4-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]-ACETIC ACID 2HCL
(R)-Cetirizine (hydrochloride)
LEVOCETIRIZINE;(R)-CETIRIZINE (HYDROCHLORIDE)
LevocetirizineDihydrochloride>
Levocetirizine Dihydrochlorid
Levocetirizine dihydrochloride USP/EP/BP
Levocetirizine Hydrochloride Impurities
Levocetirizine Dihydrochloride Powder
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Levocetirizine D4 Dihydrochloride
Levocetirizine DihydrochlorideQ: What is
Levocetirizine Dihydrochloride Q: What is the CAS Number of
Levocetirizine Dihydrochloride Q: What is the storage condition of
Levocetirizine Dihydrochloride
Levocetirizine Dihydrochloride (1359969)
(-)-Cetirizine Dihydrochloride
Xyzal Dihydrochloride
(R)-Cetirizine DiHCl
Levocetirizine HCI
LEVOCETIRIZINE HYDROCHLORIDE IP
Levocetirizine dihydrochloride IMpurity
Levocetirizine Dihydrochloride, ≥ 98.0%
Levocetirizine Dihydrochloride -IHS/IPS
130018-87-0
3008-87-0
C21H25ClN2O32ClH
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