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FLOSEQUINAN

FLOSEQUINAN Structure
CAS No.
76568-02-0
Chemical Name:
FLOSEQUINAN
Synonyms
Manoplax;BTS-49465;Flosequinon;FLOSEQUINAN;FLOSEQUINAN USP/EP/BP;7-Huom-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone;7-Fluoro-1-methyl-3-methylsulfinylquinolin-4(1H)-one;7-Fluoro-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone;4(1H)-Quinolinone, 7-fluoro-1-methyl-3-(methylsulfinyl)-
CBNumber:
CB9292729
Molecular Formula:
C11H10FNO2S
Molecular Weight:
239.27
MOL File:
76568-02-0.mol
Modify Date:
2023/9/4 15:51:00
Request For Quotation

FLOSEQUINAN Properties

Melting point 226-228°
Boiling point 423.1±45.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka -0.51±0.70(Predicted)

FLOSEQUINAN Chemical Properties,Uses,Production

Description

Flosequinan is a new mixed arteriolar and venous vasodilator useful for the treatment of patients with congestive heart failure with or without ACE inhibitors, but especially in those patients who are intolerant to ACE inhibitors. It does not cause reflex stimulation of the renin-angiotensin or sympathetic nervous system. How flosequinan achieves its direct vasodilating effect is not clear, it is thought to interfere with protein kinase C and the production of inositol triphosphate. Flosequinan is well absorbed orally, and with the relatively long half-life of its sulfone metabolite it is suitable for once a day administration.

Uses

Antihypertensive (vasodilator).

FLOSEQUINAN Preparation Products And Raw materials

Raw materials

Sodium hydride Iodic acid Dimethyl sulfide Dimethyl sulfate 2-Amino-4-fluorobenzoic acid
PHOSGENE Potassium carbonate Triethyl orthoformate Piperidine 7-fluoro-3-methanesulfinyl-1,4-dihydroquinolin-4-one
2-Chloro-4-fluorobenzoic acid 7-FLUORO-1-H-BENZO[D][1,3]OXAZINE-2,4-DIONE 4-Fluoro-2-(methylamino)benzoic acid 7-FLUORO-2-METHYLISATOIC ANHYDRIDE
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Preparation Products

FLOSEQUINAN Suppliers

Global( 17)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 8744 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 China 39990 58 Inquiry
Aikon International Limited 025-58851090 13611564524 China 15952 58 Inquiry
Suzhou yacoo science co.,Ltd 0512-87182056 18013166090 China 7300 60 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23962 58 Inquiry
kemikalieimport + 45 - 2034 3359 Europe 6699 47 Inquiry
ecochem international chemical broker +45 45 42 34 36 Europe 6385 66 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
2A PharmaChem USA (630) 737-0988 United States 6148 39 Inquiry
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Haohong Scientific Co., Ltd. 58
Aikon International Limited 58
Suzhou yacoo science co.,Ltd 60
TargetMol Chemicals Inc. 58
kemikalieimport 47
ecochem international chemical broker 66
3B Scientific Corporation 47
2A PharmaChem USA 39

FLOSEQUINAN Spectrum

FLOSEQUINAN(76568-02-0)1HNMR

76568-02-0(FLOSEQUINAN)Related Search:

BTS Flosequinan sulphone FLOSEQUINAN 2-Amino-4-Fluoro Benzaldehyde
BTS-49465 Flosequinon Manoplax 7-Fluoro-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone 7-Fluoro-1-methyl-3-methylsulfinylquinolin-4(1H)-one FLOSEQUINAN 7-Huom-1-methyl-3-(methylsulfinyl)-4(1H)-quinolinone FLOSEQUINAN USP/EP/BP 4(1H)-Quinolinone, 7-fluoro-1-methyl-3-(methylsulfinyl)- 76568-02-0 C11H10FNO2S