BTS
- CAS No.
- 1576-37-0
- Chemical Name:
- BTS
- Synonyms
- BTS;CLN3;Battenin;NSC 37123;N-Tosylbenzylamine;N-Benzyl-p-tosylaMide;LABOTEST-BB LT00786416;N-Tosylphenylmethanamine;N-Tosylbenzenemethaneamine;n-benzyl-p-toluenesulfonamid
- CBNumber:
- CB9457528
- Molecular Formula:
- C14H15NO2S
- Molecular Weight:
- 261.34
- MOL File:
- 1576-37-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 115 °C |
|---|---|
| Boiling point | 419.1±48.0 °C(Predicted) |
| Density | 1.204±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly) |
| form | White crystalline solid |
| pka | 11.54±0.30(Predicted) |
| color | White to Off-White |
| Sensitive | Light Sensitive |
| CAS DataBase Reference | 1576-37-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| RTECS | XT5490000 | |||||||||
| HS Code | 2935.90.9500 | |||||||||
| Toxicity | rat,LD,oral,> 500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 41, 1953. | |||||||||
| NFPA 704 |
|
BTS price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 203895 | BTS - CAS 1576-37-0 - Calbiochem A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC?? = ~ 5 μM) and reversibly blocks the gliding motility. | 1576-37-0 | 5MG | ₹16670.01 | 2022-06-14 | Buy |
| TCI Chemicals (India) | B3082 | N-Benzyl-p-toluenesulfonamide | 1576-37-0 | 5G | ₹6800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | B3082 | N-Benzyl-p-toluenesulfonamide | 1576-37-0 | 25G | ₹9900 | 2022-05-26 | Buy |
| ALFA India | ALF-J64910-MA | N-Benzyl-p-toluenesulfonamide | 1576-37-0 | 10mg | ₹14685 | 2022-05-26 | Buy |
| ALFA India | ALF-J64910-LB0 | N-Benzyl-p-toluenesulfonamide | 1576-37-0 | 5mg | ₹11770 | 2022-05-26 | Buy |
BTS Chemical Properties,Uses,Production
Description
BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin. It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC50 value of approximately 5 μM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 μM. BTS (2 μM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC50 = ~3 μM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.
Chemical Properties
White Solid
Uses
A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II
Biological Activity
Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.
BTS Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20366 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Hebei Duling International Trade Co. LTD | +8617333973358 | China | 15440 | 58 | Inquiry |
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