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Dinoprost tromethamine

Dinoprost tromethamine Structure
CAS No.
38562-01-5
Chemical Name:
Dinoprost tromethamine
Synonyms
583e;u14585;lutalyse;Ensaprost;u-14,583e;PGF2ALPHA;PGF2αTris;Zinoprost;haminesalt;PGF2a-THAM
CBNumber:
CB9394313
Molecular Formula:
C24H45NO8
Molecular Weight:
475.62
MOL File:
38562-01-5.mol
MSDS File:
SDS
Modify Date:
2024/1/8 17:23:13

Dinoprost tromethamine Properties

Melting point 100-101°
storage temp. -20°C
solubility H2O: 1 mg/mL Aqueous solutions are stable for 30 days at 2-8°C and for several months frozen at −0°C in single use aliquots. Avoid repeated freeze/thaw cycles.
form powder
color white
Merck 13,7970
BRN 4087514
Stability Hygroscopic
InChIKey IYGXEHDCSOYNKY-RZHHZEQLSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H360FD
Precautionary statements  P202-P264-P270-P280-P301+P312-P308+P313
Hazard Codes  T
Risk Statements  60-22
Safety Statements  53-45
WGK Germany  3
RTECS  UK8025000
8-10
HS Code  2937500000
NFPA 704
0
2 0

Dinoprost tromethamine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P0424 Prostaglandin F2α tris salt ≥99%, synthetic, powder 38562-01-5 1MG ₹11907.5 2022-06-14 Buy
Sigma-Aldrich(India) P5069 Prostaglandin F2α tris salt synthetic, suitable for cell culture 38562-01-5 1MG ₹21595.88 2022-06-14 Buy
Sigma-Aldrich(India) P0424 Prostaglandin F2α tris salt ≥99%, synthetic, powder 38562-01-5 5MG ₹29108.43 2022-06-14 Buy
Sigma-Aldrich(India) P0424 Prostaglandin F2α tris salt ≥99%, synthetic, powder 38562-01-5 10MG ₹45876.35 2022-06-14 Buy
Product number Packaging Price Buy
P0424 1MG ₹11907.5 Buy
P5069 1MG ₹21595.88 Buy
P0424 5MG ₹29108.43 Buy
P0424 10MG ₹45876.35 Buy

Dinoprost tromethamine Chemical Properties,Uses,Production

Description

Dinoprost tromethamine is a synthetic analogue of prostaglandin. F2α is an autocrine hormone present in many mammalian tissues. It is used to cause luteolysis in the cow, sow and mare. It is given as a single injection by im or sc routes, the recommended dosage rate is 25 mg cow; 10 mg sow and 5 mg mare. It is rapidly absorbed from the injection site. It has an extremely short half life of only a few minutes, it is almost completely cleared following one or two passages through the liver and/or lungs.

Chemical Properties

White Solid

Definition

dinoprost tromethamine is a synthetic analogue of the naturally occurring prostaglandin F2 alpha. Prostaglandin F2 alpha stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action on the corpus luteum.

Indications

Dinoprost tromethamine salt (Prostaglandin F2α tromethamine salt) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost tromethamine salt is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost tromethamine salt plays a key role in the onset and progression of labour.

Safety Profile

Poison by intraperitoneal, subcutaneous, intravenous, and intramuscular routes. Moderately toxic by ingestion. Human reproductive effects by intervagmal route: terminates pregnancy, effects on fertility. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also other prostaglandin entries.

Dinoprost tromethamine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 259)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Aspen Biopharma Labs Private Limited 08047620755 Hyderabad, India 17 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
Guangzhou TongYi biochemistry technology Co.,LTD +8613073028829 China 2996 58 Inquiry
Sinoway Industrial co., ltd. 0592-5800732; +8613806035118 China 992 58 Inquiry
Nantong Guangyuan Chemicl Co,Ltd +undefined17712220823 China 616 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry

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Dinoprost tromethamine Spectrum

583e 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicacid,tromet Tromethamine salt PGF2α (Prostaglandin F2α) Dinoprost TroMethaMine USP Dinorprost tromethamine (E,Z)-(1R,2R,3R,5S)-7-[3,5-Dihydroxy-2-[(3S)-(3-hydroxy-1-octenyl)]cyclopentyl]-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)@component of prostin F2 alpha, injectable Dinoprost compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) Ensaprost Dinoprost Tromethamine (50 mg) (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid 2-AMino-2-(hydroxyMethyl)-1,3-propanediol 7-[3,5-Dihydroxy-2-(3-hydroxy-1- octenyl)cyclopentyl]-5-heptenoic Acid TroMethaMine 9α,11α,15(S)-Trihydroxy-5-cis-13-trans-prostadienoic Acid TroMethaMine 9α,11α-PGF2 TroMethaMine 9α,11α-PGF2α TroMethaMine thampgf2-alpha tromethamineprostaglandinf2-alpha u-14,583e u14585 PROSTAGLANDINS F2ALPHA TRIS SALT PROSTAGLANDIN F2-ALPHA, TRIMETHAMINE SALT PROSTAGLANDIN F2ALPHA TRIS SALT PROSTAGLANDIN F2ALPHA TROMETHAMINE PROSTAGLANDIN F2ALPHA TROMETHAMINE SALT prostaglandin f2a tris salt PGF2ALPHA PGF2ALPHA THAM PGF2ALPHA-TRIS PGF2ALPHA TRIS SALT 9α,11α,15S-Trihydroxy-prosta-5Z,13E-dien-1-oic acid tris(hydroxymethyl)aminomethane salt 7-(3,5-dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-heptenoicacitham compd.withtrimethylolaminomethane haminesalt 9ALPHA, 11ALPHA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-OIC ACID, TRIS(HYDROXYMETHYL) AMINOMETHANE SALT (5z,9a,11a,13e,15s)-9,11,15-trihydroxyprosta-5,13-dienoic acid tris salt Tromethamine prostaglandin F2α PGF2a-THAM PGF2α-Tris, Prostaglandin F2α tris salt, (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt PGF2α-Tris, (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt PGF2αTris lutalyse pgf2-alphatromethamine pgf2-alphatromethaminesalt prostaglandinf2-alphatham prostaglandinf2-alphathamsalt prostaglandinf2atromethamine protaglandinf2-alpha-thamsalt DINOPROST TROMETHAMINE DINOPROST (TROMETHAMINE SALT) dinoprost, trometamol salt prostaglandin F2A tris prostaglandin F2-alpha, trometamol salt PROSTAGLANDIN F2A TRIS GAMMA-IRRADIATED CELL CULTUR PROSTAGLANDIN F2A TRIS CELL*CULTURE TEST ED [5Z,9ALPHA,11ALPHA,13E,15S]-9,11,15-TRIHYDROXYPROSTA-5,13-DIENOIC ACID TRIS SALT Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9.alpha.,11.alpha.,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) (5z,9α,11α,13e,15s)-9,11,15-trihydroxyprosta-5,13-dienoic acid tris salt 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (5Z,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oate (salt) (9CI)