ChemicalBook > Product Catalog >API >Nervous system drugs >Central stimulant drugs >alpha-Lobeline hydrochloride
alpha-Lobeline hydrochloride
- CAS No.
- 134-63-4
- Chemical Name:
- alpha-Lobeline hydrochloride
- Synonyms
- Lobelin Hydrochlorde;LOBELINE HYDROCHLORIDE;(-)-id;a-Lobeline;A-LOBELINE HCL;LOBELINE HCL, A-;(-)-LOBELINE HCL;Einecs 205-150-2;ALPHA-LOBELIN HCL;Lobeline HCl salt
- CBNumber:
- CB9404885
- Molecular Formula:
- C22H28ClNO2
- Molecular Weight:
- 373.92
- MOL File:
- 134-63-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/15 13:17:26
| Melting point | 183-185 °C (dec.)(lit.) |
|---|---|
| alpha | D20 -43° (c = 2) |
| refractive index | -57.5 ° (C=1, H2O) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 25 mg/mL |
| form | powder |
| color | white to off-white |
| optical activity | [α]20/D 56.8°, c = 2 in H2O |
| Merck | 14,5551 |
| BRN | 3920196 |
| LogP | 3.610 (est) |
| CAS DataBase Reference | 134-63-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H331 | |||||||||
| Precautionary statements | P301+P310+P330-P304+P340+P311 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/25 | |||||||||
| Safety Statements | 36/37/39-45 | |||||||||
| RIDADR | UN 1544 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OJ8490100 | |||||||||
| F | 8 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| NFPA 704 |
|
alpha-Lobeline hydrochloride price More Price(2)
alpha-Lobeline hydrochloride Chemical Properties,Uses,Production
Description
(–)-Lobeline is an alkaloid that has been found in Lobelia and has diverse biological activities. It binds to nicotinic acetylcholine receptors (nAChRs) in rat brain homogenates (Ki = 4 nM) and has antinociceptive effects in the tail-flick assay in mice. (–)-Lobeline (0.3 and 0.9 mg/kg) reduces the number of errors in a repeated acquisition procedure in the radial arm maze in rats. It also decreases immobility time in the forced swim test and feeding latency in the novelty suppressed feeding test, indicating antidepressant-like activity, in mice when administered at doses of 1 and 4 mg/kg.
Chemical Properties
White to Off-White Solid
Uses
A neuronal nicotinic acetylcholine receptor agonist. A respiratory stimulant
Biological Activity
High affinity nicotinic receptor ligand, with a K i value of 4.4 nM in rat brain.
alpha-Lobeline hydrochloride Preparation Products And Raw materials
Global( 233)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| Vyshno Bio Sciences | 91-7095439993 | Hyderabad, India | 239 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21677 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
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(?)-Lobeline hydrochloride
134-63-4
C22H27NO2HCl
Building Blocks
Asymmetric Synthesis
Chiral Building Blocks