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ChemicalBook > Product Catalogue >API >Nervous system drugs >Central stimulant drugs >alpha-Lobeline hydrochloride

alpha-Lobeline hydrochloride

alpha-Lobeline hydrochloride Structure
  • ₹9785.8
  • Product name: alpha-Lobeline hydrochloride
  • CAS: 134-63-4
  • MF: C22H28ClNO2
  • MW: 373.92
  • EINECS:205-150-2
  • MDL Number:MFCD00082455
  • Synonyms:2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONE HCL;2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONE HYDROCHLORIDE;2-[(2r,6s)-6-[(2s)-2-hydroxy-2-phenyl-ethyl]-1-methyl-2-piperidyl]-1-phenyl-ethanone hydrochloride;[2-[(2R,6S)-6-[(2S)-2-HYDROXYPHENETHYL]]-1-METHYL-2-PIPERIDYL]ACETOPHENONE HYDROCHLORIDE;(-)-LOBELINE HCL;LOBELINE HCL, A-;(-)-LOBELINE HYDROCHLORIDE;L-LOBELINE HYDROCHLORIDE
2 prices
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Brand

  • Sigma-Aldrich
  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich
  • Product number141879
  • Product description(−)-Lobeline hydrochloride 98%
  • Packaging1G
  • Price₹9785.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number141879
  • Product description(−)-Lobeline hydrochloride 98%
  • Packaging1G
  • Price₹9785.8
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 141879 (−)-Lobeline hydrochloride 98% 1G ₹9785.8 2022-06-14 Buy
Sigma-Aldrich(India) 141879 (−)-Lobeline hydrochloride 98% 1G ₹9785.8 2022-06-14 Buy

Properties

Melting point :183-185 °C (dec.)(lit.)
alpha :D20 -43° (c = 2)
refractive index :-57.5 ° (C=1, H2O)
storage temp. :Inert atmosphere,Room Temperature
solubility :H2O: 25 mg/mL
form :powder
color :white to off-white
optical activity :[α]20/D 56.8°, c = 2 in H2O
Merck :14,5551
BRN :3920196
LogP :3.610 (est)
CAS DataBase Reference :134-63-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Lobeline hydrochloride is the hydrochloride salt preparation of Lobeline, a potent agonist of the AChR (nicotinic acetylcholine receptor). Lobeline is demonstrated to increase 86Rb+ efflux at lower concentrations and to reduce 86Rb+ efflux at higher concentrations, suggesting a differential receptor subtype selectivity from nicotine and agonism through a non-nicotinic mechanism. Lobeline is also described to inhibit dopamine uptake into synaptic vesicles.

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