Methyl 2-methoxy-5-sulfamoylbenzoate
- CAS No.
- 33045-52-2
- Chemical Name:
- Methyl 2-methoxy-5-sulfamoylbenzoate
- Synonyms
- Sulpride Impurity B;Methyl2-Methoxy-5-S;Sulpiride EP Impurity B;Sulpiride Impurity B(EP);Sulpiride impurity B CRS;2-Methoxy-5-sulfamoylbenzoic;methyl 5-sulphamoyl-o-anisate;Sulpiride impurity B (S2192000);Methyl[5-Amino Sulfonyl-2-Methoxy];Methyl 2-Methoxy-5-sulphamoylbenzoa
- CBNumber:
- CB9455786
- Molecular Formula:
- C9H11NO5S
- Molecular Weight:
- 245.25
- MOL File:
- 33045-52-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/27 18:35:49
| Melting point | 175-177 °C (lit.) |
|---|---|
| Boiling point | 439.8±55.0 °C(Predicted) |
| Density | 1.360±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 9.94±0.60(Predicted) |
| color | White to Off-White |
| LogP | 0.36 |
| CAS DataBase Reference | 33045-52-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| Hazard Codes | Xi |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| HS Code | 2922500090 |
Methyl 2-methoxy-5-sulfamoylbenzoate Chemical Properties,Uses,Production
Uses
Methyl 2-methoxy-5-sulfamoylbenzoate is a reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypog lycemic agents.
Preparation
Methyl 2-methoxy-5-aminosulfonyl benzoate is an important intermediate for the synthesis of sulpiride, which is the main drug for treatment of psychiatric disorders such as schizophrenia and depression. The synthetic route of methyl 2-methoxy-5-aminosulfonyl benzoate is composed mainly of etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification, which prepared successfully with the help of salicylic acid and methyl salicylate as precursor. The raw materials of the synthetic route are salicylic acid and methyl salicylate, which was synthesized by etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification.
synthetic procedure of Methyl 2-Methoxy-5-Aminosulfonyl Benzoate
General Description
Methyl 2-methoxy-5-sulfamoylbenzoate is also referred to as 2-methoxy-5-sulfamoyl methyl benzoate or methyl 5-(aminosulphonyl)-2-methoxybenzoate.
Methyl 2-methoxy-5-sulfamoylbenzoate Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| BIOCHEMICAL & SYNTHETIC PRODUCTS PVT. LT., | +91-91-8421973722 +91-9869455944 | Telangana, India | 31 | 58 | Inquiry |
| CNS CHEMICALS | +91-9381957258 +91-9381957258 | Telangana, India | 354 | 58 | Inquiry |
| Prayosha Health Care Pvt Ltd | +91-9924448881 +91-9924448881 | Gujarat, India | 15 | 58 | Inquiry |
| Telangana Pharmatech | +91-8106025359 +91-04048501333 | Hyderabad, India | 29 | 58 | Inquiry |
| Acute Research | +91-9825068697 +91-9825068697 | Gujarat, India | 43 | 58 | Inquiry |
| Yogi Enterprise | +91-9377714435 +91-9824314435 | Gujarat, India | 91 | 58 | Inquiry |
| Medicina Lyfe Care | +91-9898789931 +91-9687603963 | Gujarat, India | 16 | 58 | Inquiry |
| Orgamine Chemicals(I) Pvt Ltd | +91-9820080281 +91-9820080281 | Maharashtra, India | 451 | 58 | Inquiry |
| Riddhesh Pharmachem | +91-9106014993 +91-9106014993 | Gujarat, India | 126 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| BIOCHEMICAL & SYNTHETIC PRODUCTS PVT. LT., | 58 |
| CNS CHEMICALS | 58 |
| Prayosha Health Care Pvt Ltd | 58 |
| Telangana Pharmatech | 58 |
| Acute Research | 58 |
| Yogi Enterprise | 58 |
| Medicina Lyfe Care | 58 |
| Orgamine Chemicals(I) Pvt Ltd | 58 |
| Riddhesh Pharmachem | 58 |
33045-52-2(Methyl 2-methoxy-5-sulfamoylbenzoate)Related Search:
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