ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Adrenal corticosteroids >Fluorometholone
Fluorometholone
- CAS No.
- 426-13-1
- Chemical Name:
- Fluorometholone
- Synonyms
- FML;Flulon;U 8614;Ursnon;Fluoron;Fluaton;FML SOP;oxylone;trilcin;Fluor-Op
- CBNumber:
- CB9461978
- Molecular Formula:
- C22H29FO4
- Molecular Weight:
- 376.46
- MOL File:
- 426-13-1.mol
- Modify Date:
- 2024/11/17 16:00:36
| Melting point | 292-303° |
|---|---|
| alpha | +52～+60°(c=1, pyridine) (D/20℃) |
| Boiling point | 527.1±50.0 °C(Predicted) |
| Density | 1.0573 (rough estimate) |
| refractive index | 55 ° (C=1, Pyridine) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) |
| form | Solid |
| pka | 12.50±0.70(Predicted) |
| color | White to Off-White |
| Water Solubility | 30mg/L(25 ºC) |
| Merck | 14,4175 |
| CAS DataBase Reference | 426-13-1(CAS DataBase Reference) |
| EPA Substance Registry System | Fluorometholone (426-13-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TU3834100 | |||||||||
| HS Code | 29189900 | |||||||||
| Toxicity | rat,LD,oral,> 2gm/kg (2000mg/kg),Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2349, 1974. | |||||||||
| NFPA 704 |
|
Fluorometholone price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | F9381 | Fluorometholone ≥98% | 426-13-1 | 100MG | ₹14180.75 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR3405 | Fluorometholone certified reference material, pharmaceutical secondary standard | 426-13-1 | 400MG | ₹21563.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | F9381 | Fluorometholone ≥98% | 426-13-1 | 500MG | ₹42737.1 | 2022-06-14 | Buy |
| TCI Chemicals (India) | F0414 | Fluorometholone | 426-13-1 | 1G | ₹11000 | 2022-05-26 | Buy |
Fluorometholone Chemical Properties,Uses,Production
Chemical Properties
White powder
Uses
Fluorometholone is a glucocorticoid; anti-inflammatory.
Definition
ChEBI: A member of the class of glucocorticoids that is Delta1-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.
General Description
Fluorometholone, 9-fluoro-11β,17-dihydroxy-6α-methylpregn-4-ene-3,20-dione(Fluor-Op, FML), lacks the typical C21 OH group of GCsand is used exclusively in ophthalmic products. The 17-acetateof fluorometholone is also used as an ophthalmic suspension(Flarex).
Fluorometholone Preparation Products And Raw materials
Global( 350)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Maharshi Pharma Chem | +91-7940359347 +91-7433927173 | Gujarat, India | 24 | 58 | Inquiry |
| Prachem Laboratories | +91-7948993109 +91-7383072020 | Gujarat, India | 44 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Bhugan Lifescience Pvt Ltd | +91-9909430337 +91-8849461798 | Gujarat, India | 23 | 58 | Inquiry |
| AKASH PHARMA EXPORTS | +91-9388123451 +91-9846039283 | Kerela, India | 470 | 58 | Inquiry |
| Innovative Synthetic Molecules | +91 40-24111684 | Hyderabad, India | 526 | 58 | Inquiry |
| Global Pharma | 08048372772Ext 809 | Mumbai, India | 70 | 58 | Inquiry |
| Add Biotec | 91-22-26731400 | Maharashtra, India | 49 | 58 | Inquiry |
| Ralington Pharma. | 91-79-48911722 | Gujarat, India | 311 | 58 | Inquiry |
| Leotus Enterprises | 08048372748Ext 179 | Vadodara, India | 48 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Maharshi Pharma Chem | 58 |
| Prachem Laboratories | 58 |
| Ralington Pharma | 58 |
| Bhugan Lifescience Pvt Ltd | 58 |
| AKASH PHARMA EXPORTS | 58 |
| Innovative Synthetic Molecules | 58 |
| Global Pharma | 58 |
| Add Biotec | 58 |
| Ralington Pharma. | 58 |
| Leotus Enterprises | 58 |
426-13-1(Fluorometholone)Related Search:
Thiophanate-methyl
Bensulfuron methyl
Kresoxim-methyl
Flumethasone
(6a,11b,16a,17a)-6,9-Difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid
chevron_left
1of4
chevron_right
(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
21-Desoxy-9a-fluoro-6-methylprednisolone
6a-Methyl-9a-fluoro-21-desoxyprednisolone
9a-Fluoro-11b,17a-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione
Flulon
Fluoron
(6S,8S,9R,10S,11S,13S,14S,17R)-17-ethanoyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Fluorometholone,11β,17α-Dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
Fluorometholone (200 mg)
luoroMethalone
(6α,11β)-9-Fluoro-11,17-dihydroxy-6-Methylpregna-1,4-diene-3,20-dione
Fluaton PVA
11β,17α-dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
FLUOROMETHOLONE,POWDER,USP
21-Desoxy-9α-fluoro-6-methylprednisolone
6α-Methyl-9α-fluoro-11β,17α-dihydroxypregna-1,4-diene-3,20-dione
6α-Methyl-9α-fluoro-21-desoxyprednisolone
Efflumidex
Fluaton
Flumetholon
Fluormetholon
Fluor-Op
FML
FML Forte
FML Liquifilm
FML SOP
Loticort
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-6-methyl-, (6α,11β)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-6α-methyl- (6CI, 7CI, 8CI)
U 8614
Ursnon
Fluorometholone solution,100ppm
FLUOROMETHOLONE
fluoromethalone
1,4-PREGNADIEN-9-ALPHA-FLUORO-6-ALPHA-METHYL-11-BETA, 17-DIOL-3,20-DIONE
11BETA,17ALPHA-DIHYDROXY-9-FLUORO-6-METHYL-1,4-PREGNADIENE-3,20-DIONE
11-BETA,17-ALPHA-DIHYDROXY-9-FLUORO-6-METHYL-4-ANDROSTEN-3-ONE
11b,17a-dihydroxy-9-fluoro-6-methyl-1,4-pregnadiene-3,20-dione
21-DESOXY-9A-FLUORO-6-ALPHA-METHYLPREDNISOLONE
9a-fluoro-11b,17a-dihydroxy-6a-methyl-1,4-pregnadiene-3,20-dione
9-FLUORO-11,17-DIHYDROXY-6-METHYLPREGNA-1,4-DIENE-3,20-DIONE
20-dione,9-fluoro-11-beta,17-dihydroxy-6-alpha-methyl-pregna-4-diene-3
9-fluoro-11-beta,17-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
cortilet
delmeson
nsc33001
oxylone
pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-6-methyl-,(6alpha,11be
pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-6-methyl-,(6-alpha,11-be
trilcin
9-alpha-fluoro-11-beta,17-alpha-dihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-6-Methyl-, (6a,11b)-
4-amino-1-methyl-3-pyrazolo[3,4-d]pyrimidinecarbonitrile
Fluorometholone 426-13-1
uorometholone
Fluorometholone Fluorometholone
Fluorometholone>
Fluorometholone RS