Bromotrimethylsilane
- CAS No.
- 2857-97-8
- Chemical Name:
- Bromotrimethylsilane
- Synonyms
- TMSBR;TRIMETHYLSILYL BROMIDE;TRIMETHYLBROMOSILANE;TMBS;(CH3)3SiBr;Silane, bromotrimethyl-;CT2928;TMS bromide;BromotrimethyL;Co-Formula CFS-978
- CBNumber:
- CB9749809
- Molecular Formula:
- C3H9BrSi
- Molecular Weight:
- 153.09
- MOL File:
- 2857-97-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/28 19:50:54
| Melting point | -43 °C |
|---|---|
| Boiling point | 79 °C(lit.) |
| Density | 1.16 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 90 °F |
| storage temp. | Store below +30°C. |
| solubility | DECOMPOSES |
| form | Liquid |
| Specific Gravity | 1.1725 |
| color | Clear colorless to yellow |
| Water Solubility | DECOMPOSES |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| BRN | 1731135 |
| Stability | Stable. Flammable. Incompatible with strong acids, strong oxidizing agents. May decompose on exposure to water or moist air. |
| CAS DataBase Reference | 2857-97-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Bromotrimethylsilane(2857-97-8) |
| EPA Substance Registry System | Silane, bromotrimethyl- (2857-97-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS02,GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H314-H335-H410 | |||||||||
| Precautionary statements | P210-P233-P273-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 10-34-29-14 | |||||||||
| Safety Statements | 16-26-36/37/39-45-8 | |||||||||
| RIDADR | UN 2920 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29310095 | |||||||||
| NFPA 704 |
|
Bromotrimethylsilane price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 92337 | Bromotrimethylsilane purum, ≥97.0% (AT) | 2857-97-8 | 5ML | ₹3117.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 92337 | Bromotrimethylsilane purum, ≥97.0% (AT) | 2857-97-8 | 25ML | ₹10738.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 92337 | Bromotrimethylsilane purum, ≥97.0% (AT) | 2857-97-8 | 100ML | ₹22645.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.14324 | Bromotrimethylsilane for synthesis | 2857-97-8 | 10ML | ₹4979.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 194409 | Bromotrimethylsilane 97% | 2857-97-8 | 5G | ₹3150.08 | 2022-06-14 | Buy |
Bromotrimethylsilane Chemical Properties,Uses,Production
Chemical Properties
Clear yellow liquid
Physical properties
bp 79°C; d 1.188 g cm?3; n20 D 1.4240; fp 32°C.
Uses
Bromotrimethylsilane is a mild and selective reagent for cleavage of lactones, epoxides,
acetals, phosphonate esters and certain ethers; effective reagent
for formation of silyl enol ethers; can function as brominating
agent.
Amines react with TMS-Br to form
isolable adducts, which react readily with ketones to form enamines
under mild conditions (eq 15).
Preparation
although many methods are reported, only a few are provided here: chlorotrimethylsilane undergoes halogen exchange with either magnesium bromide in Et2O or sodium bromide in MeCN, which allows in situ reagent formation (eq 1); alternatively, hexamethyldisilane reacts with bromine in benzene solution or neat, to afford only TMS-Br with no byproducts (eq 2).4 TMS-Br may also be generated by reaction of hexamethyldisiloxane and aluminum bromide (eq 3).However, it should be noted that the reactivity of in situ generated reagent appears to depend upon the method of preparation.
General Description
Bromotrimethylsilane is used with Cl3 to catalyze the direct allylation of a variety of alcohols with allyltrimethylsilane.
Purification Methods
Purify it by repeated fractional distillation and store it in sealed ampoules in the dark. [McCusker & Reilly J Am Chem Soc 75 1583 1953.] Also fractionate it through a 15-plate column (0.8 x 32cm packed with 1/16in single turn helices of Pt-Ir wire). [Gilliam et al. J Am Chem Soc 68 1161 1946, Pray et al. J Am Chem Soc 70 433 1948, Beilstein 4 IV 4008.]
Bromotrimethylsilane Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
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| VDL ORGANICS PVT LTD | +91-9246335727 +91-8328068806 | Telangana, India | 50 | 58 | Inquiry |
| AMINO ORGANICS | +919866989891 | Hyderabad, India | 275 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| SPD CHEMICALS | +91-7075800742 +91-7075800742 | Hyderabad, India | 214 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Spectrochem Private Limited | 08048372608Ext 246 | Maharashtra, India | 1056 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| Global Chemie | 08046043260 | Mumbai, India | 162 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| VDL ORGANICS PVT LTD | 58 |
| AMINO ORGANICS | 58 |
| JSK Chemicals | 58 |
| SPD CHEMICALS | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Spectrochem Private Limited | 58 |
| Vyas Bio Life Sciences Pvt. Ltd | 58 |
| Global Chemie | 58 |