ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Proteases >Serine Protease Inhibitors >Nafamostat mesylate
Nafamostat mesylate
- CAS No.
- 82956-11-4
- Chemical Name:
- Nafamostat mesylate
- Synonyms
- FUTHAN;FUT-175;CS-128;Coahibitor;nafamstatmesilate;Nafamostat mesila;Nafomastatmesilate;Nafamstat mesylate;Nafmostat mesylate;NAFAMOSTAT MESYLATE
- CBNumber:
- CB9764794
- Molecular Formula:
- C21H25N5O8S2
- Molecular Weight:
- 539.58
- MOL File:
- 82956-11-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/10 11:19:08
| Melting point | 259-261°C |
|---|---|
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in Water (up to 25 mg/ml). |
| form | powder |
| color | white to beige |
| Merck | 14,6350 |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at 4°C for up to 1 month, or at -80°C for up to 6 months. |
| InChIKey | SRXKIZXIRHMPFW-UHFFFAOYSA-N |
| SMILES | CS(O)(=O)=O.CS(O)(=O)=O.C(OC1=CC=C2C(=C1)C=CC(C(=N)N)=C2)(=O)C1=CC=C(NC(N)=N)C=C1 |
| CAS DataBase Reference | 82956-11-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H361fd | |||||||||
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 | |||||||||
| RIDADR | 3077 | |||||||||
| WGK Germany | nwg | |||||||||
| RTECS | DG2736000 | |||||||||
| HS Code | 29252900 | |||||||||
| NFPA 704 |
|
Nafamostat mesylate price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N0289 | Nafamostat mesylate ≥98% (HPLC) | 82956-11-4 | 10MG | ₹14473.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N0289 | Nafamostat mesylate ≥98% (HPLC) | 82956-11-4 | 50MG | ₹62081.38 | 2022-06-14 | Buy |
| TCI Chemicals (India) | N0959 | Nafamostat Mesylate | 82956-11-4 | 20MG | ₹4500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N0959 | Nafamostat Mesylate | 82956-11-4 | 100MG | ₹8700 | 2022-05-26 | Buy |
Nafamostat mesylate Chemical Properties,Uses,Production
Description
Nafamostat mesylate is a protease inhibitor useful in the treatment of acute pancreatitis. It has anticomplement, anticoagulant, antikallikrein and other activities, and thus may have additional utility in the treatment of autoimmune diseases and disseminated intravascular coagulation.
Chemical Properties
Tan to pale orange solid
Biological Activity
Broad spectrum serine protease inhibitor. Displays selectivity for human tryptase when used at relatively low concentrations. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma.
Synthesis
By p-guanidinobenzoic acid hydrochloride, 6-amidino groups-beta naphthal, 4,5-dicyano imidazole, methylene dichloride mix, 0-5 ℃ is stirred 1 hour, then improve temperature to 18-22 ℃, insulation reaction 8-12h, filters washed with dichloromethane, gained solid is 2 with methylsulfonic acid adjust pH, obtains nafamostat mesylate.
Nafamostat mesylate Preparation Products And Raw materials
Global( 385)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Bulat Pharmaceutical Pvt Ltd | +91-8448085659 +91-8448085660 | Haryana, India | 123 | 58 | Inquiry |
| Prajna generics pvt ltd | +91-9441174873 +91-9441174873 | Hyderabad, India | 24 | 58 | Inquiry |
| CNS CHEMICALS | +91-9381957258 +91-9381957258 | Telangana, India | 354 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Stellence Pharmscience Private Limited | 08068970604Ext 488 | Karnataka, India | 22 | 58 | Inquiry |
| Prajna Generics Private Limited | 08048250185Ext 545 | Hyderabad, India | 24 | 58 | Inquiry |
| Cns Chemicals | 08066085913Ext 735 | Hyderabad, India | 262 | 58 | Inquiry |
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Nafamostat mesilate C21H25N5O8S2 high quality Casnumber： 82956-11-4
Nafamostat mesylate, 98%, broad spectrum, potent protease inhibitor
Nafamostat mesila
Nafamostat mesylate Manufacturer/High quality/Best price/In stock CAS NO.82956-11-4
CS-128
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Coahibitor
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Nafamostat Mesylate >
Nafmostat mesylate
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Nafamostat Mesylate (10mM in DMSO)
Supply Nafamostat Mesylate CAS: 82956-11-4
Nafamostat Mesylate for Treatment Pancreatitis CAS No.:?82956-11-4
[13C6]-Nafamostat mesylate
FUT-175
FUTHAN
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Nafamostat mesilate (FUT-175)
Naphtholimus mesylate
Nafamostat Mesylate CRS
Nafamostate Mesylate
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82956-11-4
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C19H17N5O22C4O3S
C19H17N5O22CH4O3SC21H25N5O8S2
C19H17N5O22CH3SO3H
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Inhibitors
Aromatics
Intermediates & Fine Chemicals