Nafamostat mesylate
- ₹4500 - ₹62081.38
- Product name: Nafamostat mesylate
- CAS: 82956-11-4
- MF: C21H25N5O8S2
- MW: 539.58
- EINECS:692-168-2
- MDL Number:MFCD00941430
- Synonyms:4-((aminoiminomethyl)amino)-benzoicaci6-(aminoiminomethyl)-2-naphthalenyl ;6-carbaMiMidoylnaphthalen-2-yl 4-guanidinobenzoate diMethanesulfonate;[amino-[6-[[4-(diaminomethyleneazaniumyl)phenyl]-oxomethoxy]-2-naphthyl]methylene]ammonium;[amino-[6-[4-(diaminomethyleneazaniumyl)benzoyl]oxy-2-naphthyl]methylene]ammonium;[amino-[6-[4-(diaminomethylideneazaniumyl)benzoyl]oxynaphthalen-2-yl]methylidene]azanium;[amino-[6-[4-(diaminomethylideneazaniumyl)phenyl]carbonyloxynaphthalen-2-yl]methylidene]azanium;Nafamostat mesylate, >=98%;5-methyl-1-{6-[(7-oxo-7h-furo[3,2-g]chromen-9-yl)oxy]hexyl}pyrimidine-2,4(1h,3h)-dione
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 20MG
- 50MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberN0959
- Product descriptionNafamostat Mesylate
- Packaging20MG
- Price₹4500
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberN0959
- Product descriptionNafamostat Mesylate
- Packaging100MG
- Price₹8700
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN0289
- Product descriptionNafamostat mesylate ≥98% (HPLC)
- Packaging50MG
- Price₹62081.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberN0289
- Product descriptionNafamostat mesylate ≥98% (HPLC)
- Packaging10MG
- Price₹14473.03
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | N0959 | Nafamostat Mesylate | 20MG | ₹4500 | 2022-05-26 | Buy |
TCI Chemicals (India) | N0959 | Nafamostat Mesylate | 100MG | ₹8700 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | N0289 | Nafamostat mesylate ≥98% (HPLC) | 50MG | ₹62081.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | N0289 | Nafamostat mesylate ≥98% (HPLC) | 10MG | ₹14473.03 | 2022-06-14 | Buy |
Properties
Melting point :259-261°C
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in Water (up to 25 mg/ml).
form :powder
color :white to beige
Merck :14,6350
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at 4°C for up to 1 month, or at -80°C for up to 6 months.
InChI :InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;2*1-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);2*1H3,(H,2,3,4)
InChIKey :SRXKIZXIRHMPFW-UHFFFAOYSA-N
SMILES :CS(O)(=O)=O.CS(O)(=O)=O.C(OC1=CC=C2C(=C1)C=CC(C(=N)N)=C2)(=O)C1=CC=C(NC(N)=N)C=C1
CAS DataBase Reference :82956-11-4(CAS DataBase Reference)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in Water (up to 25 mg/ml).
form :powder
color :white to beige
Merck :14,6350
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at 4°C for up to 1 month, or at -80°C for up to 6 months.
InChI :InChI=1S/C19H17N5O2.2CH4O3S/c20-17(21)14-2-1-13-10-16(8-5-12(13)9-14)26-18(25)11-3-6-15(7-4-11)24-19(22)23;2*1-5(2,3)4/h1-10H,(H3,20,21)(H4,22,23,24);2*1H3,(H,2,3,4)
InChIKey :SRXKIZXIRHMPFW-UHFFFAOYSA-N
SMILES :CS(O)(=O)=O.CS(O)(=O)=O.C(OC1=CC=C2C(=C1)C=CC(C(=N)N)=C2)(=O)C1=CC=C(NC(N)=N)C=C1
CAS DataBase Reference :82956-11-4(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | ||||||||||||
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Description
Nafamostat is a serine protease inhibitor that is capable of inhibiting trypsin (a digestive system protease; Ki = 15 nM), tryptase (a mast cell protease; Ki = 95.3 pM), and additional proteases in the coagulation cascade including thrombin (Ki = 0.84 μM). In a mouse model of allergic asthma, a dose of 300 mg/kg nafamostat mesylate has been shown to inhibit serine proteolytic activity, to decrease circulating levels of eosinophils and lymphocytes in bronchoalveolar lavage fluid, and to reduce interleukin-13 and eotaxin production associated with antigen-induced airway eosinophilia and goblet cell hyperplasia.More related product prices
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