2,5-Dimethylaniline

2,5-Dimethylaniline Structure
CAS No.
95-78-3
Chemical Name:
2,5-Dimethylaniline
Synonyms
2,5-XYLIDINE;ai3-16559;AKOS 91126;P-XYLIDINE;para-xylidine;2-amino-p-xylene;AKOS BBS-00003675;2-Amino-1,4-xylene;3,6-DIMETHYLANILINE;2,5-DIMETHYLANILINE
CBNumber:
CB9854710
Molecular Formula:
C8H11N
Molecular Weight:
121.18
MOL File:
95-78-3.mol
MSDS File:
SDS
Modify Date:
2024/8/17 21:30:02

2,5-Dimethylaniline Properties

Melting point 11.5 °C(lit.)
Boiling point 218 °C(lit.)
Density 0.973 g/mL at 25 °C(lit.)
vapor pressure 20Pa
refractive index n20/D 1.559(lit.)
Flash point 201 °F
storage temp. Store below +30°C.
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sparingly)
form Liquid
pka pK1:4.53(+1) (25°C)
color Clear yellow to red-brown
Water Solubility <0.1 g/100 mL at 18 ºC
Merck 14,10084
BRN 2205178
LogP 1.83
CAS DataBase Reference 95-78-3(CAS DataBase Reference)
IARC 3 (Vol. 16, Sup 7) 1987
NIST Chemistry Reference Benzenamine, 2,5-dimethyl-(95-78-3)
EPA Substance Registry System 2,5-Dimethylaniline (95-78-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301+H311+H331-H373-H411
Precautionary statements  P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314
Hazard Codes  T,N,Xn
Risk Statements  23/24/25-33-51/53-48/20
Safety Statements  28-36/37-45-61-28A
RIDADR  UN 1711 6.1/PG 2
WGK Germany  3
RTECS  ZE9100000
8-10-23
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29214910
NFPA 704
1
3 0

2,5-Dimethylaniline price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 102253 2,5-Dimethylaniline 99% 95-78-3 100ML ₹4124.33 2022-06-14 Buy
TCI Chemicals (India) D0668 2,5-Dimethylaniline min. 97.0 % 95-78-3 25G ₹1600 2022-05-26 Buy
TCI Chemicals (India) D0668 2,5-Dimethylaniline min. 97.0 % 95-78-3 500G ₹10900 2022-05-26 Buy
Product number Packaging Price Buy
102253 100ML ₹4124.33 Buy
D0668 25G ₹1600 Buy
D0668 500G ₹10900 Buy

2,5-Dimethylaniline Chemical Properties,Uses,Production

Chemical Properties

clear yellow to red-brown liquid

Uses

2,5-Dimethylaniline is widely used as raw materials to produce imaging chemicals like organic dyes and pigments. It is also used in the production of antioxidants, pharmaceutical, agricultural, rubber chemicals and other target organic molecules. 2,5-Dimethylaniline was also used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity. The Fourier transform infrared (FTIR) and Raman spectra of 2,5-dimethylaniline was studied5. It induced transcription of lccIV.

Definition

ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 5-positions are replaced by methyl groups. It is used in the manufacture of dyes and other chemicals.

General Description

Dark brown liquid.

Air & Water Reactions

2,5-Dimethylaniline may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

2,5-Dimethylaniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

2,5-Dimethylaniline is combustible.

Safety Profile

Suspected carcinogen. A poison. Moderately toxic by ingestion. Quesuonable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.

Purification Methods

Convert p-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry over KOH and fractionally distil. The acetyl derivative has m 142o (from H2O or toluene), and the benzoyl derivative has m 140o (from EtOH). [Beilstein 12 H 1135, 12 IV 2567.]

2,5-Dimethylaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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ai3-16559 Aniline, 2,5-dimethyl- para-xylidine P-XYLIDINE 2,5-Dimethylaniline,99% 2,5-DIMETHYLANILINE / 2,5-XYLIDINE Benzenamine, 2,5-dimethyl- 2,5-DIMETHYLBENZAMINE AKOS BBS-00003675 AKOS 91126 5-METHYL-O-TOLUIDINE 6-METHYL-M-TOLUIDINE 3,6-DIMETHYLANILINE 3-amino-1,4-dimethylbenzene 1-AMINO-2,5-DIMETHYLBENZENE 2-AMINO-4-METHYLTOLUENE 2-AMINO-1,4-DIMETHYLBENZENE 2,5-XYLIDINE 2,5-DIMETHYLANILINE 2,5-Dimethylaniline, 98+% 2,5-Xylidine (NH2=1) 2,5-dimethyl-anilin 2,5-dimethyl-benzenamin 2,5-Dimethylbenzenamine 2,5-dimethyl-Benzenamine 2,5-Dimethylbenzeneamine 2,5-Dimethylphenylamine 2-amino-1,4-dimethyl-benzen 2-Amino-1,4-xylene 2-amino-p-xylene 5-Amino-1,4-dimethylbenzene 2,5-Xylidine, 2-Amino-1,4-dimethylbenzene, 2-Amino-p-xylene 2,5-Dimethylaniline,2,5-Xylidine, 2-Amino-1,4-dimethylbenzene, 2-Amino-p-xylene 2,5-DiMethylaniline, 99% 100GR 2,5-DiMethylaniline, 99% 5GR 2,5-Xylidine p-Xylidine 2,5-DIMETHYLANILINE FOR SYNTHESIS 2,5-two Methyl aniline 2,5-Dimethylaniline > TIANFU CHEM-2,5-Dimethylaniline 95-78-3 95783 Amines Building Blocks C8 Nitrogen Compounds Organic Building Blocks Phenyls & Phenyl-Het Anilines, Aromatic Amines and Nitro Compounds Amines Phenyls & Phenyl-Het Intermediates