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Oxytocin acetate

Oxytocin acetate Structure
CAS No.
6233-83-6
Chemical Name:
Oxytocin acetate
Synonyms
Oxytocin Identification;Pitocin Acetate;Synpitan Acetate;Uteracon Acetate;Orasthin Acetate;OXYTOCIN ACETATE;Perlacton Acetate;Syntocinon Acetate;Oxytocin (O0700000);Oxytocin Acetate NO
CBNumber:
CB9927175
Molecular Formula:
C43H66N12O12S2.C2H4O2
Molecular Weight:
1067.24
MOL File:
6233-83-6.mol
MSDS File:
SDS
Modify Date:
2026/11/4 17:01:59

Oxytocin acetate Properties

storage temp. Store at -20°C
solubility DMSO:44.0(Max Conc. mg/mL);41.23(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);46.85(Max Conc. mM)
form A crystalline solid
color White to off-white
Sequence Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6)
InChIKey DSZOEVVLZMNAEH-SIVBSZNNNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)Exclamation Mark (GHS07)
GHS08,GHS07
Signal word  Danger
Hazard statements  H413-H360-H302
Precautionary statements  P264-P270-P301+P312-P330-P501
RIDADR  UN 2811 6.1 / PGII
HS Code  2937190000
NFPA 704
0
4 0

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Oxytocin acetate Chemical Properties,Uses,Production

Description

Oxytocin acetate is an analog of oxytocin, a hormone that stimulates the uterus during labor. It is synthesized by chemically conjugation oxytocin with acetic acid. The stability of this molecule has been proven to be higher than that of oxytocin. This drug demonstrates a stronger binding affinity for the oxytocin receptor, which may be attributed to its increased molecular weight. Additionally, oxytocin acetate has been observed to increase levels of growth factors and fatty acids in tissues when administered intramuscularly, while also stimulating neurotransmission. It exhibits a shorter onset latency and a longer duration of action compared to other analogs. Apart from its medical applications, oxytocin acetate can also serve as a disinfectant in cosmetic use and as an amide-forming agent in organic synthesis reactions.

Chemical Properties

White Solid

Uses

Oxytocin acetate is the salt form of oxytocin and has a more stable structure than oxytocin. Oxytocin is a cyclic nonpeptide that is recommended by the World Health Organization (WHO) for the prevention and treatment of postpartum haemorrhage. Oxytocin is used to therapeutically induce labour and stimulate lactation, and is also the drug of choice for the prevention of postpartum haemorrhage. Oxytocin has also recently been tested for the treatment of social phobia, autism, alcoholism and schizophrenia, and has been investigated for its potential modulatory role in antinociception[1].

Mechanism of action

The actions of oxytocin are mediated by a single G protein-coupled receptor distributed in many peripheral tissues and specific brain areas. Oxytocin secreted into the circulation stimulates uterine contractions during labor and stimulates milk ejection during lactation.

References

[1] MOSTAFA GHASEMISARABBADIEH; Benjamín R S; Sveinbjrn Gizurarson. The effect of trehalose, antioxidants, and acetate buffer concentration on oxytocin stability[J]. Journal of Peptide Science, 2021. DOI:10.1002/psc.3324.

Oxytocin acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 133)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6666 58 Inquiry
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Oxytocin Identification (15 mg) (COLD SHIPMENT REQUIRED) Orasthin Acetate Oxytocin Monoacetate Perlacton Acetate Pitocin Acetate Synpitan Acetate Syntocinon Acetate Uteracon Acetate Oxytocin, monoacetate (salt) Oxytocic hormone acetate α-Hypophamine acetate Oxytocin (O0700000) Oxytocin Acetate(acetate) parturition,α-Hypophamine,Oxytocin Receptor,protective,Oxytocin acetate,lactation,OXTR,antioxidant,Oxytocic hormone,inhibit,prosocial behavior,trauma,anti-inflammatory,Oxytocin,hypothalamic peptide,Inhibitor,Endogenous Metabolite OXYTOCIN ACETATE (S)-N-((S)-1-((2-Amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-((S)-sec-butyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamide acetate Oxytocin acetate, 10 mM in DMSO Oxytocin acetate (α-Hypophamine acetate Oxytocin Identification Oxytocin Acetate NO 6233-83-6 C43H66N12O12S2C2H4O C45H70N12O14S2 Amino Acids & Derivatives Intermediates & Fine Chemicals Pharmaceuticals Oxytocin