Quinagolide hydrochloride
- CAS No.
- 94424-50-7
- Chemical Name:
- Quinagolide hydrochloride
- Synonyms
- SDZ 205-502;CV205-502 hydrochloride;Norprolac Hydrochloride;QUINAGOLIDE HYDROCHLORIDE;Quinagolide hydrochloride (CV205-502 hydrochloride);(3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride;rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride;(3α,4aα,10aβ)-N,N-Diethyl-N'-
(1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride;(+/-)-N,N-diethyl-N'-<(3α,4aα,10aβ)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzo
quinolinyl>sulfamide hydrochloride
- CBNumber:
- CB9995839
- Molecular Formula:
- C20H34ClN3O3S
- Molecular Weight:
- 432.02
- MOL File:
- 94424-50-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:42
| Melting point | 234-236° |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 43 mg/mL (99.53 mM) |
| form | Solid |
| color | White to off-white |
| CAS DataBase Reference | 94424-50-7(CAS DataBase Reference) |
Quinagolide hydrochloride Chemical Properties,Uses,Production
Description
Quinagolide is a potent and specific non-ergot dopamine D2 agonist launched in the Netherlands for the treatment of hyperprolactinemia. Quinagolide is effective in inhibiting prolactin secretion by human pituitary tumor and hyperprolactinemia in vitro and in viva A daily dose of as low as 60 pg is able to achieve a pronounced and prolonged suppressive effect on serum prolactin and growth hormone secretion. It is also effective in providing relief from associated effects such as infertility, galactorrhea, oligomenorrhea, amenorrhea, loss of IibMo and impotence. Compared with the most widely used antiprolactin, bromocriptine, quinagolide is more potent in vivo with a longer duration of action and fewer side effects. A recent study showed that acute administration of quinagolide suppresses growth hormone secretion in acromegalic patients and thus could serve as an alternative therapy in acromegaly.
Uses
Quinagolide is a nonergot dopamine D2-receptor agonist. Quinagolide acts as an prolactin inhibitor.
Quinagolide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Quinagolide hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
| Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
| Shanghai Ziqi Biological Technology Co., Ltd. | 400-811-9081 13681619662 | CHINA | 6192 | 58 | Inquiry |
| Shanghai Hao Biological Technology Co., Ltd. | 021-58116080 18019263206 | CHINA | 6921 | 58 | Inquiry |
| Shanghai Yubo Biotechnology Co., Ltd. | 021-51875103 15026509758 | CHINA | 6322 | 58 | Inquiry |
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