Tetracosactide acetate
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Tetracosactide acetate 속성
- 밀도
- 1.47±0.1 g/cm3(Predicted)
- 저장 조건
- −20°C
- 용해도
- 물에 거의 용해되지 않습니다.
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- White to off-white
- 수용성
- 물에 용해됨
- 시퀀스
- H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH
- 안정성
- 흡습성
- InChIKey
- ZOEFCCMDUURGSE-SQKVDDBVSA-N
- CAS 데이터베이스
- 16960-16-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
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RTECS 번호 | GM7915000 | ||
HS 번호 | 2937220000 | ||
유해 물질 데이터 | 16960-16-0(Hazardous Substances Data) |
그림문자(GHS): | |||||||||||||||||||||||||||||
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신호 어: | Danger | ||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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Tetracosactide acetate C화학적 특성, 용도, 생산
개요
Cosyntropin (Tetracosactide acetate) is a synthetic polypeptide that consists of amino acid residues 1 through 24 of human ACTH, but that has the full biological activity of its parent. Because it is of synthetic origin, it is less allergenic than ACTH of natural origin. Cosyntropin is used as a diagnostic agent in the screening of patients suspected of having adrenocortical insufficiency. Normally, parenteral administration of cosyntropin acts rapidly on the adrenal cortex to effect release of plasma hydrocortisone; when performing the test, the hydrocortisone levels are compared to a control blood sample taken earlier.화학적 성질
White or yellow, amorphous powder.정의
ChEBI: A synthetic peptide that is identical to the 24-amino acid segment at the N-terminal of adrenocorticotropic hormone (corticotropin). A segment similar in all species, it contains the biological activity that stimulates production of cort costeroids in the adrenal cortex. It is used diagnostically to investigate adrenocortical insufficiency.Indications
Cosyntropin (Cortrosyn) is a polypeptide that consists solely of the first 24 amino acids of corticotropin. It appears to offer an advantage over the naturally occurring hormone in that it has a longer duration of action and lacks the antigenic portion of corticotropin. Although the short cosyntropin test is recognized as a valid screening test to assess adrenocortical insufficiency, the overnight metyrapone test or insulin hypoglycemia test may prove more sensitive.일반 설명
Cosyntropin (Cortrosyn) is a syntheticpeptide containing the first 24 amino acids of natural corticotropin.Cosyntropin is used as a diagnostic agent to testfor adrenal cortical deficiency. Plasma hydrocortisone concentrationis determined before and 30 minutes after theadministration of 250 g of cosyntropin. Most normal responses result in an approximate doubling of the basalhydrocortisone concentration in 30 to 60 minutes. If the responseis not normal, adrenal insufficiency is indicated.Such adrenal insufficiency could be a result of either adrenalor pituitary malfunction, and further testing is requiredto distinguish between the two. Cosyntropin (250 μg infusedwithin 4–8 hours) or corticotropin (80–120 U/day for3–4 days) is administered. Patients with functional adrenaltissue should respond to this dosage. Patients who respondaccordingly are suspected of hypopituitarism, and the diagnosiscan be confirmed by other tests for pituitary function.Patients who have Addison disease, however, show little orno response.부작용
Common side effects of Tetracosactide acetate may include: an allergic reaction (hives; difficult breathing; swelling of your face, lips, tongue, or throat); fast or slow heartbeats; increased blood pressure; rash; swelling in your hands or feet.Tetracosactide acetate 준비 용품 및 원자재
원자재
준비 용품
Tetracosactide acetate 공급 업체
글로벌( 264)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Cellmano Biotech Limited | 0551-65326643 18156095617 |
info@cellmano.com | China | 999 | 58 |
Apextide Co Ltd | +86-15300650552 +86-15300650552 |
info@apextide.com | China | 71 | 58 |
BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
Zhejiang Hangyu API Co., Ltd | +8617531972939 |
anna@api-made.com | China | 2944 | 58 |
Shanghai Getian Industrial Co., LTD | +86-15373193816 +86-15373193816 |
mike@ge-tian.com | China | 269 | 58 |
Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 |
3684455296@qq.com | China | 9311 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 |
asdf@shanghaihg.cn | China | 265 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 |
info@fortunachem.com | China | 5989 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Tetracosactide acetate 관련 검색:
코르티손-21-아세트산
Corticotropin
Teduglutide
BPP 9A
Tolvaptan
LHRH
Ipamorelin
Deslorelin
Abarelix
Semaglutide
Teriparatide acetate
Terlipressin acetate
Teriparatideacetate
Adrenocorticotropic hormone
MET-GLU-HIS-PHE-ARG-TRP-GLY
H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-NH2
PHE-PRO
AC-LYS-PRO-VAL-NH2