4-AMINO-1,8-NAPHTHALIMIDE
4-AMINO-1,8-NAPHTHALIMIDE
- CAS:
- 1742-95-6
- MF:
- C12H8N2O2
- MW:
- 212.2
Suppliers by country/region
Properties
- Melting point:
- 360 °C
- Boiling point:
- 352.04°C (rough estimate)
- Density
- 1.105 g/mL at 25 °C(lit.)
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.6000 (estimate)
- storage temp.
- -20°C
- solubility
- Soluble in DMSO
- form
- Orange solid.
- pka
- 9.53±0.20(Predicted)
- color
- Yellow to brown
- Water Solubility
- 354mg/L at 25℃
- LogP
- 1.08
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P305+P351+P338
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-37/39
- WGK Germany
- 3
- RTECS
- DE4081000
- TSCA
- Yes
- HS Code
- 29251995
Use
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM). It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation. 4-ANI is used to study the role of PARP activity in various cell systems.
0 India supplier list of "4-AMINO-1,8-NAPHTHALIMIDE"
- Product Name:4-Amino-1,8-naphthalimide
- Products Intro:Brand:sigma aldrich | Product Number:A0966
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:4-Amino-1,8-naphthalimide
- Products Intro:Brand:ajchemicals | Product Number:JDH-100956 | Purity:95%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:6-aminobenzo[de]isoquinoline-1,3-dione
- Products Intro:Brand:thermofisher.in | Product Number:ALF-J64358-MC | Purity:97%
- Company Type: Trader
- Country/Region: Maharashtra,INDIA
- Product Name:4-amino-1,8-naphthalimide
- Products Intro:Purity: 0.98 | Package: 1KG;10KG;50KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:4-AMINO-1,8-NAPHTHALIMIDE
- Products Intro:Purity: 0.99 | Package: 25g
- Company Type: Trader
- Country/Region: CHINA
- Product Name:4-Amino-1,8-naphthalimide
- Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Hot selling
- Company Type: Trader
- Country/Region: CHINA
- Product Name:4-Amino-1,8-naphthalimide
- Products Intro:Purity: 99 | Package: 5KG;1KG,25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Palmitoylethanolamide,GHK-Cu,Copper tripeptide-1,Nicotinamide Riboside Chloride,NMN,Ergothioneine
- Product Name:4-amino-1,8-naphthalimide
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:4-Amino-1,8-naphthalimide
- Products Intro:Purity: 95% | Package: $16.9/50mg;$62.9/250mg;$191.9/1g;$863.9/5g;Bulk package | CustNote: 95%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:4-amino-1-hydroxy-7H-purin-6-ol
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A811628
- Company Type: Reagent
- Country/Region: CHINA